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Web Desc
Wnt and beta-Catenin Signaling in Development and Disease
Organizer(s): Mariann Bienz and Hans C. Clevers
Date: April 07 - 12, 2006
Location: Snowbird Resort, Snowbird, UT, USA
Sponsored by Genentech, Inc.
Summary of Meeting:
The Wnt/b-catenin pathway is a highly conserved signaling cascade that plays key roles during animal development. Deregulation of this pathway is often associated with cancer, especially in the human intestinal epithelium where hyperactive b-catenin is thought to initiate colorectal cancer. The basic outline of the Wnt/b-catenin cascade has been known since its discovery ten years ago by genetic analysis in Drosophila. How its components interact molecularly to transduce the Wnt signal from the plasma membrane to the nucleus is still poorly understood. Indeed, recent research in model systems has revealed new core components of this pathway. The main goal of this meeting is to promote insight into the molecular and cell-biological mechanisms of Wnt signal transduction in various cellular systems. Basic researchers and the pharmaceutical/biotechnology industry are invited to discuss how to exploit model systems and how to translate knowledge from these into drug development.
Scholarship Deadline: December 7 2005
Discounted Abstract Deadline: December 7 2005
Abstract Deadline: December 30 2005
Discounted Registration Deadline: February 7 2006
We gratefully acknowledge additional support for this conference from:
Cell Signaling Technology, Inc.Genentech, Inc.Novartis Institutes for BioMedical Research
We gratefully acknowledge the generous grant for this conference provided by:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Grant No. 1R13 HD052386-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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