Mast Cells, Basophils, and IgE: Host Defense and Disease Organizer(s): Joshua A. Boyce, K. Frank Austen, Jean S. Marshall and William E. Paul Date: January 20 - 24, 2007
Location: Copper Mountain Resort, Copper Mountain, CO, USAMast cells, basophils, and IgE form a strongly conserved interface between innate and adaptive mucosal immune systems. Each cell is a sensitive detector of environmental perturbations, to which they respond by generating and releasing a distinctive profile of mediators. The development of progressively more sophisticated experimental models has permitted the recognition of clear-cut and novel functions for mast cells and basophils in mediating effector cell recruitment, facilitating antigen presentation, inducing and amplifying immune responses, and modulating host responses in disease models. This program will focus on new aspects of development and trafficking of both cell lineages, homeostatic controls of cell activation, in-depth examination of mast cell and basophil-derived mediators, the roles of these cells in both allergic (IgE-mediated) and non-allergic disease, and therapeutic modulation of their roles in both mouse models and human disease. Scholarship Deadline: September 20 2006 Discounted Abstract Deadline: September 20 2006 Abstract Deadline: October 23 2006 Discounted Registration Deadline: November 20 2006 We gratefully acknowledge additional support for this conference from:  |