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Web Desc
Ubiquitin and Signaling
Organizer(s): Brenda A. Schulman, Tony Hunter, Mark W. Hochstrasser and Claudio A.P. Joazeiro
Date: February 04 - 09, 2007
Location: Big Sky Resort, Big Sky, MT, USA
Supported by the Director's Fund
Summary of Meeting:
Our understanding of how ubiquitin regulates cellular functions has greatly expanded in the past several years, spurred by discoveries of protein families involved in ubiquitin conjugation and deconjugation, and of nonproteasomal signaling functions for ubiquitin and ubiquitin-related proteins. The first Keystone meeting on Ubiquitin and Signaling, in February 2005, was highly successful, based on both strong attendance and feedback from the participants. The significance and timely nature of the ubiquitination problem is highlighted by the 2004 Nobel Prize in Chemistry honoring pioneers in the field. We anticipate a further explosion in our understanding of ubiquitination over the next few years, and propose a meeting that captures this momentum. Ubiquitin regulates an enormous range of cellular processes. There are almost as many predicted human ubiquitin ligases as protein kinases, and the ubiquitin system has been directly implicated in numerous diseases, including many cancers and neurodegenerative disorders. Many protein domains have recently been associated with ubiquitination, deubiquitination or ubiquitin binding. These are found in several thousand proteins, presenting the challenge to determine their functions and mechanistic links to the ubiquitin system. In addition, the ubiquitin system is now widely recognized as a target for pharmacological intervention in various diseases. The goal of the meeting is to bring together experts from different areas of ubiquitin research as well as experts from other fields that are beginning to be affected by our knowledge of ubiquitin function. We expect that this meeting will foster extensive discussion of ubiquitin system function in both normal and pathological states.
Scholarship Deadline: October 4 2006
Discounted Abstract Deadline: October 4 2006
Abstract Deadline: November 2 2006
Discounted Registration Deadline: December 4 2006
We gratefully acknowledge additional support for this conference from:
Boston Biochem, an R&D Systems CompanyEducational donation provided by AmgenENZO LIFE SCIENCES INTERNATIONAL, INC.Invitrogen CorporationMerck Research Laboratories
Proteome Resources LLC
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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