Intracellular and Intercellular Signaling in Dendritic Cell Function joint with Imaging Immune Responses Organizer(s): Muriel Moser, Caetano Reis e Sousa and Yong-Jun Liu Date: February 25 - March 02, 2007
Location: Keystone Resort, Keystone, CO, USAThe myriad of cellular interactions that ultimately regulate immune responses are mediated by specific ligand-receptor interactions that, in turn, trigger intracellular signaling pathways. Recent advances in basic cellular and molecular immunology have provided a framework for understanding how the immune response is initiated and regulated, integrating different cell types, molecules and signaling pathways. The Keystone meeting will focus on the immunomodulatory capacity of dendritic cells (DC), a critical cell type in immune regulation. Particular emphasis will be placed on the following. • Receptors that play an important function in pathogen recognition by DC as well as receptors involved in DC processes such as cell adhesion, migration and signaling • The potential role of activating and inhibitory ligands and receptors in modulating DC function • The intracellular signaling triggered by these receptors and the mechanism by which they activate or inhibit immune effector functions and determine cellular lifespan • The molecules involved in cross-talk between DC and other cells and tissues • The mechanisms of DC interactions with the tumor microenvironment • The DC regulatory pathways regulating immunity versus tolerance Scholarship Deadline: October 25 2006 Discounted Abstract Deadline: October 25 2006 Abstract Deadline: November 27 2006 Discounted Registration Deadline: December 26 2006 We gratefully acknowledge additional support for this conference from:  |