Tumor Suppressors and Stem Cell Biology Organizer(s): Sean J. Morrison and Alejandro Sánchez Alvarado Date: February 24 - 29, 2008
Location: Fairmont Hotel Vancouver, Vancouver, BC, CanadaStem cells play key roles in the development, maintenance, and reproduction of all known multicellular organisms. Stem cells operate in a wide variety of biological contexts from homeostasis to regeneration and must be subject to complex and robust regulation. Recent evidence suggests that tumor suppressor mechanisms, originally discovered for their ability to inhibit tumorigenesis, also play widespread roles in the physiological regulation of stem cells. Tumor suppressors play critical roles in the regulation of tissue homeostasis, stem cell self-renewal, regeneration, and aging. This reveals mechanistic links between the regulation of stem cells, and the regulation of cancer cells that could potentially be exploited to target cancer and to enhance regeneration. The dual roles of these mechanisms in stem cell and cancer biology illuminate the evolved balance between the promotion of regeneration and the suppression of cancer. Scholarship Deadline: October 24 2007 Discounted Abstract Deadline: October 24 2007 Abstract Deadline: November 26 2007 Discounted Registration Deadline: December 26 2007 We gratefully acknowledge additional support for this conference from:  |