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Web Desc
Complex Traits: Biologic and Therapeutic Insights
Organizer(s): Trudy F.C. Mackay, Lon Cardon and David R. Cox
Date: February 29 - March 05, 2008
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Supported by the Director's Fund
Summary of Meeting:
Most phenotypic variation in populations, including variation in susceptibility to common human diseases, is attributable to segregating alleles of multiple genes, whose expression is dependent on the environment. Rapidly increasing knowledge about variation in genome sequence and gene expression will facilitate understanding the relationships of genotype to complex phenotypes and the evolutionary mechanisms shaping variation for complex traits, in humans and model organisms. Major questions to be solved regarding the genetic architecture of complex traits include the following: (1) the relative prevalence of common and rare variants; (2) whether causal variation is typically regulatory or structural; (3) how many segregating alleles affect any given trait and their pleiotropic effects on other traits; and (4) the extent to which allelic effects depend on other segregating alleles and the environment. This meeting aims to address these questions by bringing together investigators from population and quantitative genetics, genomics, and with expertise in model systems and humans.
Scholarship Deadline: October 30 2007
Discounted Abstract Deadline: October 30 2007
Abstract Deadline: November 29 2007
Discounted Registration Deadline: December 31 2007
We gratefully acknowledge additional support for this conference from:
Integrated DNA Technologies
We gratefully acknowledge the generous grant for this conference provided by:

National Human Genome Research Institute (NHGRI)
Grant No. 1R13HG004585-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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