RNAi, MicroRNA, and Non-Coding RNA
Organizer(s): Judy Lieberman and Phillip A. SharpDate: March 25 - 30, 2008
Location: Whistler Conference Centre, Whistler, BC, Canada
RNA interference (RNAi) describes a variety of evolutionarily conserved mechanisms for regulating gene transcription and post-transcriptional events that are important for controlling development and cell proliferation, survival, differentiation and effector functions. RNAi also protects the genome from transposons and viruses. This meeting will explore recent developments in understanding the molecular mechanisms and cell biology of RNA-based post-transcriptional silencing and for maintaining regions of silenced chromatin. It will consider methods to uncover regulatory networks of endogenous microRNAs and their target genes and illustrative examples in a variety of organisms. Recent advances in harnessing RNA interference for genetic screening and therapeutic gene silencing will also be explored.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Isis Pharmaceuticals, Inc.
Mirus Bio LLC