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Web Desc
G Protein-Coupled Receptors: New Insights in Functional Regulation and Clinical Application
Organizer(s): Heidi E. Hamm, P. Jeffrey Conn, Jean-Philippe Pin and Olivier Civelli
Date: May 18 - 23, 2008
Location: INEC Killarney Convention Centre, Killarney, Co. Kerry, Ireland
In collaboration with Science Foundation Ireland; Part of the Translational Medicine Series, Sponsored by Pfizer Global Research & Development
Summary of Meeting:
The G-protein-coupled-receptor (GPCR) family accounts for almost 3% of the human genome and encompasses the largest number of receptors identified to date. Further, GPCRs have proven to be one of the primary targets for therapeutic drug intervention. Work in the field is rapidly progressing through the identification of structural aspects of activation, dimerization and its functional significance, ligand-directed signaling, de-orphanization of GPCRs and their signaling pathways, allosteric modulators of GPCR activation, as well as novel interacting protein complexes and their correlate signaling cascades. This Keystone Symposia meeting will focus on these important aspects of GPCRs as well as how they regulate functional systems such as sleep, stress and feeding. Finally, the effect of genetic disease on GPCR activation and signaling will be discussed.
Scholarship Deadline: January 18 2008
Discounted Abstract Deadline: January 18 2008
Abstract Deadline: February 19 2008
Discounted Registration Deadline: March 31 2008
We gratefully acknowledge additional support for this conference from:
Fáilte IrelandMerck & Co., Inc.Pfizer Global Research & DevelopmentScience Foundation Ireland
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Addex Pharmaceuticals SA

Merck & Co., Inc.

Senomyx, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Mental Health (NIMH)
Grant No. 1R13MH083445-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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