Leukocyte Trafficking joint with Chemokines and Chemokine Receptors Organizer(s): Ulrich H. von Andrian, Federica Sallusto and Klaus Ley Date: January 13 - 18, 2008
Location: Keystone Resort, Keystone, CO, USARemarkable progress has been made in understanding the cellular and molecular mechanisms that govern the intravascular recruitment, extravascular migration and functional regulation of immune cells by visualizing cell-cell interactions using powerful intravital microscopy and flow cytometry techniques. The identification of peptide- and lipid-based regulators of immune cell entry and exit and the structure-function relationship of leukocyte adhesion molecules at atomic resolution have resulted in a refined understanding of how leukocyte subset differentiation modifies migratory ability. Early clinical results with drugs such as natalizumab, which interferes with leukocyte trafficking, have demonstrated not only marked therapeutic efficacy in autoimmune diseases, but also potentially fatal immunosuppression that remains poorly understood. This meeting will bring together experts from a variety of fields to present and synthesize our current mechanistic insights into the regulation of protective and pathological immune responses and to determine how this knowledge can be translated to better and safer therapies. Scholarship Deadline: September 13 2007 Discounted Abstract Deadline: September 13 2007 Abstract Deadline: October 16 2007 Discounted Registration Deadline: November 13 2007 We gratefully acknowledge additional support for this conference from:   We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Merck Serono International S.A.
Revotar Biopharmaceuticals AG
|