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Web Desc
Molecular, Cellular, Physiological, and Pathogenic Responses to Hypoxia
joint with Molecular Mechanisms of Angiogenesis in Development and Disease
Organizer(s): Gregg L. Semenza, Nanduri R. Prabhakar and Lorenz Poellinger
Date: January 15 - 20, 2008
Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada
Supported by the Director's Fund
Summary of Meeting:
Oxygen is the substrate of multicellular life. Reduced oxygen availability (hypoxia) is sensed and transduced into changes in the activity or expression of cellular macromolecules. These responses impact on all areas of biology and medicine. The goals of the meeting are: • To understand the molecular mechanisms underlying responses to hypoxia that affect protein activity, protein synthesis, protein stability, mRNA synthesis, and mRNA stability, including the role of hypoxia-inducible factor 1 as a master regulator of oxygen homeostasis and its oxygen-dependent regulation by prolyl and asparaginyl hydroxylases. • To understand the role of hypoxia as a stimulus for normal developmental and physiological processes, including hypoxia-induced changes in vascularization. • To understand the role of hypoxia in the pathogenesis of common human diseases including cardiovascular disease, cancer, chronic lung disease, and diabetes, which account for the majority of deaths in developed countries. • The development of novel therapeutic strategies that target hypoxia response pathways.
Scholarship Deadline: September 17 2007
Discounted Abstract Deadline: September 17 2007
Abstract Deadline: October 22 2007
Discounted Registration Deadline: November 19 2007
We gratefully acknowledge additional support for this conference from:
GeneBlue CorporationMerck & Co., Inc.Ruskinn Technology Ltd, a division of the Baker Company, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Wyeth Pharmaceuticals
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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