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Web Desc
Cell Death and Cellular Senescence
joint with Cell Death in the Immune System
Organizer(s): Jacqueline A. Lees, Sally A. Kornbluth and Gerard I. Evan
Date: February 07 - 12, 2008
Location: Beaver Run Resort, Breckenridge, CO, USA
Supported by the Director's Fund
Summary of Meeting:
Cell death is known to play a critical role in both normal development and human disease. We have a good understanding of the proteins that constitute the apoptotic machinery as well as the signaling pathways that regulate this process. Many of these regulatory proteins can also induce cellular senescence, a state of irreversible cell arrest. After some initial speculation that cellular senescence might be primarily a phenomenon of cultured cells, there is now unequivocal evidence that cellular senescence occurs in vivo in response to both telomere erosion and oncogenic activation and, furthermore, that this plays a key role in tissue maintenance and tumor suppression. This meeting will explore the fundamental mechanisms that control cell death and cellular senescence and discuss how each of these processes impact both normal development and tumor suppression. To achieve this goal, the meeting assembles a broad spectrum of speakers whose interests span a variety of model organisms. The Keynote Speaker, Craig Thompson, will discuss the relationship between metabolic status and cell survival. This meeting will be held in conjunction with “Cell Death in the Immune System”. Joint sessions will include the core apoptotic machinery, cell death and cellular homeostasis, signaling and apoptosis, and autophagy, inflammation and apoptosis.
Scholarship Deadline: October 8 2007
Discounted Abstract Deadline: October 8 2007
Abstract Deadline: November 7 2007
Discounted Registration Deadline: December 10 2007
We gratefully acknowledge additional support for this conference from:
Merck & Co., Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA130252-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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