The Transient Receptor Potential Ion Channel Superfamily Organizer(s): James W. Putney, Bernd Nilius and Craig Montell Date: September 18 - 23, 2007 Location: Beaver Run Resort, Breckenridge, CO, USAIn recent years, knowledge of TRP channel biology has increased at a tremendous pace. These channels are now known to be regulated in two general ways: by physical perturbations (i.e., temperature, mechanical) or by classical signal transduction cascades (most commonly phospholipases). In addition, mutations in TRP channels are known to be the basis for a number of inherited diseases, including mucolipidosis and polycystic kidney disease. However, there is a great deal of controversy regarding the mechanisms of activation and regulation of many TRPs, especially those thought to be involved in the long elusive mechanism of store-operated channels. This symposium will highlight current knowledge of structure, function, regulation and pharmacology of the TRPs, especially with regard to current controversies. Additionally, the roles of TRPs in diseases will be addressed, including the potential for treating diseases through knowledge of their regulation, and through design of therapeutic agents to modify their behavior. Scholarship Deadline: May 18 2007 Discounted Abstract Deadline: May 18 2007 Abstract Deadline: June 19 2007 Discounted Registration Deadline: July 18 2007 We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Novartis Institutes for BioMedical Research
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