Deregulation of Transcription in Cancer: Controlling Cell Fate Decisions
Organizer(s): Beverly M. Emerson and Edison T. LiuDate: June 21 - 26, 2009
Location: INEC Killarney Convention Centre, Killarney, Co. Kerry, Ireland
Transcription is an intricate process that is regulated with exquisite specificity at both the genetic and epigenetic levels through such aspects as chromatin and core RNA polymerase machinery. Sophisticated mechanisms have been recently deciphered concerning how specific genes and pathways are deregulated in human cancers. Master cancer regulators are commonly transcription factors. Yet a great disparity exists between the nonspecificity of most cancer therapies and this advanced understanding of aberrant gene expression. This conference will focus on exploiting novel mechanistic information to generate more efficacious targeted therapies . Current insights into the mechanisms by which specific genes are deregulated in cancer, the resulting transcriptome signature for particular cancers, and state-of-the-art therapeutic approaches using small molecules or RNA interference will be presented. The goals of this meeting are to explore how transcription as a regulator for cell fate outcomes can be parlayed into specific cancer therapies.
Scholarship Deadline: February 23 2009
Discounted Abstract Deadline: February 23 2009
Abstract Deadline: March 24 2009
Discounted Registration Deadline: May 8 2009
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Merck & Co., Inc.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: