PI 3-Kinase Signaling in Disease joint with Complex Lipids in Biology: Signaling, Compartmentalization and Disease Organizer(s): Peter M. Finan, Jean Zhao and Lewis C. Cantley Date: April 22 - 27, 2009
Location: Resort at Squaw Creek, Olympic Valley, CA, USAThe PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors. Scholarship Deadline: December 23 2008 Discounted Abstract Deadline: December 23 2008 Abstract Deadline: January 26 2009 Discounted Registration Deadline: February 23 2009 We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
GlaxoSmithKline
Intellikine, Inc.
Novartis Institutes for BioMedical Research
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