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Web Desc
PI 3-Kinase Signaling in Disease
joint with Complex Lipids in Biology: Signaling, Compartmentalization and Disease
Organizer(s): Peter M. Finan, Jean Zhao and Lewis C. Cantley
Date: April 22 - 27, 2009
Location: Resort at Squaw Creek, Olympic Valley, CA, USA
Sponsored by Amgen Inc. and Novartis Institutes for BioMedical Research
Summary of Meeting:
The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.
Scholarship Deadline: December 23 2008
Discounted Abstract Deadline: December 23 2008
Abstract Deadline: January 26 2009
Discounted Registration Deadline: February 23 2009
We gratefully acknowledge additional support for this conference from:
Avanti Polar Lipids, Inc.Cell Signaling Technology, Inc.Educational donation provided by AmgenInvitrogen CorporationNovartis Institutes for BioMedical ResearchVertex Pharmaceuticals Incorporated
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

GlaxoSmithKline

Intellikine, Inc.

Novartis Institutes for BioMedical Research
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Cell Press
We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA139718-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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