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Sunday, February 21 | 3:00PM - 7:30PM
Registration
Room: Rio Grande A


Sunday, February 21 | 6:30PM - 7:30PM
Refreshments
Room: Rio Grande A


Sunday, February 21 | 7:30PM - 8:30PM
Keynote Address
Room: Bataan

Speaker 1 of 1
Alexander Y. Rudensky, HHMI/Memorial Sloan Kettering Cancer Center, USA
T cells in the framework of immunological tolerance

Monday, February 22 | 7:00AM - 8:00AM
Breakfast
Room: Rio Grande B,C,D


Monday, February 22 | 8:00AM - 11:00AM
Signaling Negative Selection of Autoreactive Lymphocytes
Room: Bataan

Speaker 1 of 5
Chang-Zheng Chen, Stanford University, USA
Immune Modulation: Lessons and Puzzles from the miR81 Family of Genes

Monday, February 22 | 8:00AM - 11:00AM
Signaling Negative Selection of Autoreactive Lymphocytes
Room: Bataan

Speaker 2 of 5
* Eric M. Verdin, Buck Institute for Research on Aging, USA
HDAC7 and Autoimmunity

Monday, February 22 | 8:00AM - 11:00AM
Signaling Negative Selection of Autoreactive Lymphocytes
Room: Bataan

Speaker 3 of 5
Philippe Bouillet, Walter and Eliza Hall Institute of Medical Research, Australia
Bim Kills Cells Mostly by Inhibiting the Bcl-2 Pro-Survival Proteins

Monday, February 22 | 8:00AM - 11:00AM
Signaling Negative Selection of Autoreactive Lymphocytes
Room: Bataan

Speaker 4 of 5
Jane H. Buckner, Benaroya Research Institute at Virginia Mason, USA
Blunted BCR Signaling, a Source of Lost Tolerance in Autoimmunity

Monday, February 22 | 8:00AM - 11:00AM
Signaling Negative Selection of Autoreactive Lymphocytes
Room: Bataan

Speaker 5 of 5
Maria A. Gutierrez, University of Texas Southwestern Medical Center, USA
Short Talk: Separate Checkpoints Regulate Plasma Cell Accumulation and IgG Autoantibody Production in Lyn-/- Mice

Monday, February 22 | 9:20AM - 9:40AM
Coffee Break
Room: Rio Grande B,C


Monday, February 22 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Monday, February 22 | 11:00AM - 1:00PM
Poster Setup
Room: Rio Grande A,B,C


Monday, February 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Rio Grande A,B,C


Monday, February 22 | 2:30PM - 4:30PM
Workshop 1
Room: Bataan

Speaker 1 of 8
* Kristin V. Tarbell, Amgen, USA

Monday, February 22 | 2:30PM - 4:30PM
Workshop 1
Room: Bataan

Speaker 2 of 8
* Zhibin Chen, University of Miami, USA

Monday, February 22 | 2:30PM - 4:30PM
Workshop 1
Room: Bataan

Speaker 3 of 8
Hsin-Jung Joyce Wu, University of Arizona, USA
Gut-Residing Segmented Filamentous Bacteria can Trigger Autoimmune Arthritis via T Helper 17 Cells

Monday, February 22 | 2:30PM - 4:30PM
Workshop 1
Room: Bataan

Speaker 4 of 8
Yong Fan, University of Pittsburgh, Children's Hospital of Pittsburgh, USA
Autoimmune Diabetes Induced by Thymic Medullary Epithelium-Specific Deletion of Insulin

Monday, February 22 | 2:30PM - 4:30PM
Workshop 1
Room: Bataan

Speaker 5 of 8
Brandy Lynn Houser, Harvard University, USA
Two Distinct Subsets of Macrophages at the Human Maternal-Fetal Interface: Neither Proinflammatory nor Immunosuppressive

Monday, February 22 | 2:30PM - 4:30PM
Workshop 1
Room: Bataan

Speaker 6 of 8
Siamak Jabbarzadeh Tabrizi, Kyushu University, Japan
BCR Signaling Regulates the Expression of IRAK Proteins in Human B Cell Subsets

Monday, February 22 | 2:30PM - 4:30PM
Workshop 1
Room: Bataan

Speaker 7 of 8
Scott M. Lieberman, Children's Hospital of Philadelphia, USA
Characterizing Natural CD4+Foxp3+ Regulatory T Cells by Anatomical Location

Monday, February 22 | 2:30PM - 4:30PM
Workshop 1
Room: Bataan

Speaker 8 of 8
Heather Niederer, University of Cambridge, UK
Copy Number, Linkage Disequilibrium and Disease Association in the FCGR Locus

Monday, February 22 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Monday, February 22 | 5:00PM - 7:00PM
Early Moments in Autoimmunity
Room: Bataan

Speaker 1 of 4
Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA
Tolerogenic and Immunogenic DCs

Monday, February 22 | 5:00PM - 7:00PM
Early Moments in Autoimmunity
Room: Bataan

Speaker 2 of 4
* Teresa P. DiLorenzo, Albert Einstein College of Medicine, USA
Autoimmunity and Tolerance in Type 1 Diabetes

Monday, February 22 | 5:00PM - 7:00PM
Early Moments in Autoimmunity
Room: Bataan

Speaker 3 of 4
Partha S. Biswas, University of Pittsburgh, USA
Short Talk: ROCK2 and IRF4: A Novel Interaction Regulating IL-17 and IL-21 Production and the Development of Autoimmunity

Monday, February 22 | 5:00PM - 7:00PM
Early Moments in Autoimmunity
Room: Bataan

Speaker 4 of 4
Lars Rönnblom, Uppsala Universitet, Sweden
Controls of the Unfolding of Lupus

Monday, February 22 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Rio Grande A,B,C


Monday, February 22 | 7:30PM - 10:00PM
Poster Session 1
Room: Rio Grande A,B,C


Tuesday, February 23 | 7:00AM - 8:00AM
Breakfast
Room: Rio Grande B,C,D


Tuesday, February 23 | 8:00AM - 11:00AM
B Cell Effectors and Regulators
Room: Bataan

Speaker 1 of 5
Robert Brink, Garvan Institute of Medical Research, Australia
Early B cell differentiation and the germinal centre response

Tuesday, February 23 | 8:00AM - 11:00AM
B Cell Effectors and Regulators
Room: Bataan

Speaker 2 of 5
* Betty Diamond, Feinstein Institute for Medical Research, USA
Regulation of GC-matured B cells

Tuesday, February 23 | 8:00AM - 11:00AM
B Cell Effectors and Regulators
Room: Bataan

Speaker 3 of 5
Claudia Mauri, University College London, UK
Regulatory B Cells in Health and in Patients with SLE

Tuesday, February 23 | 8:00AM - 11:00AM
B Cell Effectors and Regulators
Room: Bataan

Speaker 4 of 5
Gregg J. Silverman, New York University Langone Medical Center, USA
Regulatory Natural Antibodies Control Inflammatory Responses and Protect From Autoimmune Disease

Tuesday, February 23 | 8:00AM - 11:00AM
B Cell Effectors and Regulators
Room: Bataan

Speaker 5 of 5
Tomabu G. Adjobimey, Institute for Medical Immunology Microbiology and Parasitology, Germany
Short Talk: Regulatory T Cells Induce IgG4 Production by B Cells through GITR/GITR-L Interaction, IL-10 and TGF-beta

Tuesday, February 23 | 9:20AM - 9:40AM
Coffee Break
Room: Rio Grande B,C


Tuesday, February 23 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Tuesday, February 23 | 11:00AM - 1:00PM
Poster Setup
Room: Rio Grande A,B,C


Tuesday, February 23 | 1:00PM - 10:00PM
Poster Viewing
Room: Rio Grande A,B,C


Tuesday, February 23 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Tuesday, February 23 | 5:00PM - 7:00PM
Braking Autoimmunity
Room: Bataan

Speaker 1 of 4
* Diane Mathis, Harvard Medical School, USA
Molecular Pathways Controlling Autoimmunity

Tuesday, February 23 | 5:00PM - 7:00PM
Braking Autoimmunity
Room: Bataan

Speaker 2 of 4
Shohei Hori, RIKEN Research Center for Allergy and Immunology, Japan
Stability and Plasticity in Regulatory T Cell Differentiation

Tuesday, February 23 | 5:00PM - 7:00PM
Braking Autoimmunity
Room: Bataan

Speaker 3 of 4
Juan J. Lafaille, New York University School of Medicine, USA
Anergy and Tolerance

Tuesday, February 23 | 5:00PM - 7:00PM
Braking Autoimmunity
Room: Bataan

Speaker 4 of 4
Anneleen Bosma, University College London, UK
Short Talk: Lipid Antigen Presentation by B Cells is Important to Trigger iNKT Cell Expansion for Mediation of an Anti-Inflammatory Response

Tuesday, February 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Rio Grande A,B,C


Tuesday, February 23 | 7:30PM - 10:00PM
Poster Session 2
Room: Rio Grande A,B,C


Wednesday, February 24 | 7:00AM - 8:00AM
Breakfast
Room: Rio Grande B,C,D


Wednesday, February 24 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance I
Room: Bataan

Speaker 1 of 4
Bruce Compton Richardson, University of Michigan, USA
Chromatin Structure and Immune Activation in Autoimmunity

Wednesday, February 24 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance I
Room: Bataan

Speaker 2 of 4
Ian R. Rifkin, Boston University, USA
Toll-like Receptor Signaling Pathways and Lupus Pathogenesis

Wednesday, February 24 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance I
Room: Bataan

Speaker 3 of 4
Steven E. Shoelson, Harvard Medical School, Joslin Diabetes Center, USA
The Adipocyte and the Monocyte

Wednesday, February 24 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance I
Room: Bataan

Speaker 4 of 4
* Jeffrey V. Ravetch, Rockefeller University, USA
The Up- and Down-Side of Immune Complexes

Wednesday, February 24 | 9:20AM - 9:40AM
Coffee Break
Room: Rio Grande B,C


Wednesday, February 24 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Wednesday, February 24 | 11:15AM - 1:00PM
Poster Setup
Room: Rio Grande A,B,C


Wednesday, February 24 | 1:00PM - 10:00PM
Poster Viewing
Room: Rio Grande A,B,C


Wednesday, February 24 | 2:30PM - 4:30PM
Workshop 2
Room: Bataan

Speaker 1 of 7
* Alessandra Pernis, Weill Cornell Medicine, USA

Wednesday, February 24 | 2:30PM - 4:30PM
Workshop 2
Room: Bataan

Speaker 2 of 7
* William M. Ridgway, University of Cincinnati College of Medicine, USA

Wednesday, February 24 | 2:30PM - 4:30PM
Workshop 2
Room: Bataan

Speaker 3 of 7
Donald M. Simons, AbbVie Bioresearch Center, USA
Inflammatory Monocytes from Arthritic Mice Induce Th17 Cell Differentiation

Wednesday, February 24 | 2:30PM - 4:30PM
Workshop 2
Room: Bataan

Speaker 4 of 7
Reiko Takahashi, Keio University School of Medicine, Japan
SOCS1 Mediates Stabilization of Foxp3 Expression in Treg Cells

Wednesday, February 24 | 2:30PM - 4:30PM
Workshop 2
Room: Bataan

Speaker 5 of 7
Charis E. Teh, John Curtin School of Medical Research, Australia
Combinatorial Defects in Central and Peripheral Tolerance Checkpoints Precipitate Autoimmune Pancreatitis and Sialadenitis

Wednesday, February 24 | 2:30PM - 4:30PM
Workshop 2
Room: Bataan

Speaker 6 of 7
Falk Weih, Leibniz-Institute for Age Research, Germany
Role of RelA and RelB in Medullary Thymic Epithelial Cells in the Establishment of Immunological Self-Tolerance

Wednesday, February 24 | 2:30PM - 4:30PM
Workshop 2
Room: Bataan

Speaker 7 of 7
Duane R. Wesemann, Harvard Medical School, USA
Peripheral B Cell Receptor Editing

Wednesday, February 24 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, February 24 | 5:00PM - 7:00PM
Tissue Response: Turning the Other Cheek (Or Not)
Room: Bataan

Speaker 1 of 4
Bryce A. Binstadt, University of Minnesota, USA
Effector Pathways in Multi-Organ Autoimmunity

Wednesday, February 24 | 5:00PM - 7:00PM
Tissue Response: Turning the Other Cheek (Or Not)
Room: Bataan

Speaker 2 of 4
Matthias Kretzler, University of Michigan, USA
A Systems View of Regulatory Networks in Lupus Nephritis

Wednesday, February 24 | 5:00PM - 7:00PM
Tissue Response: Turning the Other Cheek (Or Not)
Room: Bataan

Speaker 3 of 4
* William M. Ridgway, University of Cincinnati College of Medicine, USA
Why Some Tissues are Targeted for Damage

Wednesday, February 24 | 5:00PM - 7:00PM
Tissue Response: Turning the Other Cheek (Or Not)
Room: Bataan

Speaker 4 of 4
Javier Ochoa-Repáraz, Eastern Washington University, USA
Short Talk: Oral Treatment with Purified Polysaccharide A (PSA) of Human Commensal Bacteroides Fragilis Protects Against Experimental CNS Demyelinating Disease

Wednesday, February 24 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Rio Grande A,B,C


Wednesday, February 24 | 7:30PM - 10:00PM
Poster Session 3
Room: Rio Grande A,B,C


Thursday, February 25 | 7:00AM - 8:00AM
Breakfast
Room: Rio Grande B,C,D


Thursday, February 25 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance II
Room: Bataan

Speaker 1 of 5
Charlotte Cunningham-Rundles, Mount Sinai Medical Center, USA
Immunodeficiency and Autoimmunity in Man

Thursday, February 25 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance II
Room: Bataan

Speaker 2 of 5
Roberta Pelanda, University of Colorado Denver, USA
Antigen and BAFF Receptors Guide the Selection and Differentiation of Immature B Cells

Thursday, February 25 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance II
Room: Bataan

Speaker 3 of 5
* Carola G. Vinuesa, Australian National University, Australia
T Follicular Helper Cells in the Control of Autoimmune Disease

Thursday, February 25 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance II
Room: Bataan

Speaker 4 of 5
Jarish N. Cohen, University of Virginia Health Systems, USA
Short Talk: Lymphatic Endothelial Cells Mediate CD8+ T Cell Peripheral Tolerance by Direct Antigen Presentation that is Independent of Aire

Thursday, February 25 | 8:00AM - 11:00AM
Regulating Thresholds for Activation and Tolerance II
Room: Bataan

Speaker 5 of 5
Norihito Kawasaki, The Scripps Research Institute, USA
Short Talk: CD22 is a Potent Negative Regulator of TLRs in B Cells

Thursday, February 25 | 9:20AM - 9:40AM
Coffee Break
Room: Rio Grande B,C


Thursday, February 25 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Thursday, February 25 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, February 25 | 5:00PM - 7:00PM
Novel Insights and Novel Therapeutics
Room: Bataan

Speaker 1 of 3
Antonio Uccelli, Azienda Ospedaliera Universitaria San Martino di Genova, Italy
Mesenchymal Stem Cells: A New Cell Therapy for Autoimmune Diseases

Thursday, February 25 | 5:00PM - 7:00PM
Novel Insights and Novel Therapeutics
Room: Bataan

Speaker 2 of 3
* Kevin J. Tracey, Feinstein Institute for Medical Research, USA
Reflexive Control of Autoinflammation and Immunity

Thursday, February 25 | 5:00PM - 7:00PM
Novel Insights and Novel Therapeutics
Room: Bataan

Speaker 3 of 3
Marijke Niens, The Jackson Laboratory, USA
Short Talk: Prevention of Type 1 Diabetes in “HLA Humanized” NOD Mice by a Multi-Peptide Coupled-Cell Approach

Thursday, February 25 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Rio Grande A,B,C


Thursday, February 25 | 8:00PM - 11:00PM
Entertainment
Room: Rio Grande


Thursday, February 25 | 8:00PM - 11:00PM
Cash Bar
Room: Rio Grande


Friday, February 26 | 10:25AM - 10:25AM
Departure


*Session Chair.

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