Cell Death Pathways: Apoptosis, Autophagy and Necrosis joint with Metabolism and Cancer Progression Organizer(s): Guido Kroemer, Junying Yuan and Eileen P. White Date: March 12 - 17, 2010
Location: Fairmont Hotel Vancouver, Vancouver, BC, CanadaHomeostatic and pathological cell death can occur through a multiplicity of different mechanisms including apoptosis, autophagy, necrosis and others. The morphological and functional definitions of distinct cell death modalities are emerging, and the relationships between different lethal pathways are being determined. However, the exact nature of the molecular switches that determine which subroutines cells disintegrate are elusive. Moreover, the relative contributions of different cell death modalities to the avoidance of cancer or degenerative diseases remain to be defined. In cancer, in particular, where defects in cell death are prevalent and the survival of undead cells enables progression and treatment resistance, restoration of cell death pathways is an important and achievable therapeutic goal. Finally, distinct cell death modalities may remain immunologically silent or trigger an immune response, through mechanisms that are still elusive. The 2010 Keystone Symposia meeting on Cell Death will address the normal regulation and pathogenic dysfunction of distinct cell death modalities, present new strategies for therapeutic cancer cell induction and address the immunogenicity of distinct cell death types. Scholarship Deadline: November 12 2009 Discounted Abstract Deadline: November 12 2009 Abstract Deadline: December 10 2009 Discounted Registration Deadline: January 12 2010 We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Abbott Laboratories
Genentech, Inc.
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