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Web Desc
Nuclear Receptors: Signaling, Gene Regulation and Cancer
joint with Nuclear Receptors: Development, Physiology and Disease
Organizer(s): W. Lee Kraus, Myles Brown and Karen Elizabeth Knudsen
Date: March 21 - 26, 2010
Location: Keystone Resort, Keystone, CO, USA
Supported by The Directors' Fund
Summary of Meeting:
Nuclear receptors (NRs) comprise a large family of ligand-regulated transcription factors that play critical roles in physiology and disease. Much of the focus has been on the nuclear actions of NRs, including interactions with coregulators, modulation of chromatin structure, and regulation of gene expression. Recent studies, however, have also suggested a role for membrane- or cytoplasmic-initiated actions of NRs and crosstalk with other cellular signaling pathways. Current studies are aimed at understanding how the ligand-dependent molecular actions of NRs, including their subcellular localization, binding across the genome, and interaction with the proteome, connect to their roles in physiological and pathophysiological processes, including hormone-regulated cancers. In addition, NRs are being explored as targets for drug development, with many compounds on the market or in ongoing clinical trials. This meeting will highlight recent breakthroughs in NR research, promote interactions between scientists from industry and academia, and provide opportunities for senior scientists to interact with younger researchers and trainees.
Scholarship Deadline: November 23 2009
Discounted Abstract Deadline: November 23 2009
Abstract Deadline: December 28 2009
Discounted Registration Deadline: January 22 2010
We gratefully acknowledge additional support for this conference from:
Cayman Chemical Company, Inc.GTx, Inc.Integrated DNA Technologies
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Educational donation provided by Amgen


Geoffrey Greene
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK084688-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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