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Web Desc
New Directions in Small Molecule Drug Discovery
joint with Computer-Aided Drug Design
Organizer(s): William J. Greenlee, George Hartman and Anna K. Mapp
Date: April 20 - 25, 2010
Location: Fairmont Chateau Whistler, Whistler, BC, Canada
Sponsored by AstraZeneca Pharmaceuticals, L.P. and Takeda Pharmaceutical Company Limited
Summary of Meeting:
The purpose of this meeting is to highlight exciting new opportunities in the discovery of small molecule drug candidates, including the following: • Novel targets for small molecules, including disruption of protein-protein interactions, allosteric modulation of receptors and enzymes, and direct interactions with transcription factors. • Enabling technologies for the discovery of new small molecule leads, including diversity-oriented screening, fragment screening, and affinity screening. • The most successful structure-based design approaches to the optimization of leads. A focus of the conference will be successful applications structure-based design in the discovery of therapeutics for the treatment of HCV infection (protease inhibitors) and cancer (protein kinase inhibitors). A session comprising first-time disclosures of Phase 2 clinical candidates will illustrate successful applications of structure-based design in drug discovery.
Scholarship Deadline: December 20 2009
Discounted Abstract Deadline: December 21 2009
Abstract Deadline: January 20 2010
Discounted Registration Deadline: February 23 2010
We gratefully acknowledge additional support for this conference from:
AstraZeneca Pharmaceuticals, L.P.Biogen IdecCytokinetics, Inc.Takeda Pharmaceutical Company Limited
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Abbott Laboratories

Bristol-Myers Squibb Company

Heptares Therapeutics Ltd

Merck & Co., Inc.

Merck Research Laboratories

Sanofi US

Schering-Plough Research Institute

Tibotec BVBA
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Pubget Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of General Medical Sciences (NIGMS)
Grant No. 1R13GM093404-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

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