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Web Desc
PI 3-Kinase Signaling Pathways
joint with Inositide Signaling in Pharmacology and Disease
Organizer(s): Bart Vanhaesebroeck, Sabina Cosulich and Ramon Parsons
Date: February 13 - 18, 2011
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Bayer USA Foundation and Genentech, Inc.
Summary of Meeting:
The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the development of new PI 3-kinase inhibitors that are currently entering the clinic. The balance between modulating PI 3-kinase activity in a pathophysiological setting, while avoiding unwanted side effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and (pre)clinical data with new PI 3-kinase inhibitors.
Scholarship Deadline: October 14 2010
Discounted Abstract Deadline: October 14 2010
Abstract Deadline: November 18 2010
Discounted Registration Deadline: December 14 2010
We gratefully acknowledge additional support for this conference from:
Bayer USA FoundationCell Signaling Technology, Inc.
Genentech, Inc.
Intellikine, Inc.Santa Cruz Biotechnology, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

AstraZeneca

Calistoga Pharmaceuticals, Inc.

Genentech, Inc.

Sanofi US
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Portland Press Ltd
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK084688-02
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

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