Protein-RNA Interactions in Biology and Disease Organizer(s): Thomas Tuschl, Mikiko C. Siomi and Gideon Dreyfuss Date: March 04 - 09, 2012 Location: Hilton Santa Fe Historic Plaza Hotel, Santa Fe, NM, USACellular functions depend on numerous protein-coding and noncoding RNAs and the RNA-binding proteins (RBPs) associated with them, which form ribonucleoprotein complexes (RNPs). Mutations that disrupt either the RNA or protein components of RNPs or the factors required for their assembly can be deleterious. The discovery of disease-causing mutations in RNAs or their interacting RBPs not only adds to our growing understanding of RNA biology and chemistry, but also offers new therapeutic targets and contributes to ongoing efforts in developing mRNA-targeting antisense and RNAi therapeutics. This meeting focuses on a general understanding of post-transcriptional gene regulation and how perturbation of complex networks of RNA-protein and RNA-RNP interactions triggers disease. Scholarship Deadline: November 2 2011 Discounted Abstract Deadline: November 2 2011 Abstract Deadline: December 8 2011 Discounted Registration Deadline: January 5 2012 We gratefully acknowledge additional support for this conference from:  We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:  We gratefully acknowledge the generous grant for this conference provided by: National Institute of Neurological Disorders and Stroke (NINDS)Grant No. 1R13NS076178-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. |