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Sunday, March 03 | 4:00PM - 8:00PM
Arrival and Registration
Room: Keystone Lodge Foyer


Monday, March 04 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Monday, March 04 | 8:00AM - 9:00AM
Welcome and Keynote Address

Speaker 1 of 3
Miriam Merad, Mount Sinai School of Medicine, USA
Welcome Remarks

Monday, March 04 | 8:00AM - 9:00AM
Welcome and Keynote Address

Speaker 2 of 3
* Bart N. Lambrecht, VIB, Ghent University, Belgium

Monday, March 04 | 8:00AM - 9:00AM
Welcome and Keynote Address

Speaker 3 of 3
Michel C. Nussenzweig, HHMI/Rockefeller University, USA
Ralph Steinman and the Dendritic Cell Discovery

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 1 of 6
* Miriam Merad, Mount Sinai School of Medicine, USA
Nature versus Nurture Control of the Dendritic Cells Lineage

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 2 of 6
Boris Reizis, New York University Langone Medical Center, USA
Regulation of Plasmacytoid Dendritic Cell Development and Function

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 3 of 6
Bernard Malissen, Centre d'Immunologie de Marseille-Luminy, France
Fine-Grained Analysis of the Macrophages and Dendritic Cells Present in the Mouse Skin

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 4 of 6
* Kenneth M. Murphy, HHMI/Washington University School of Medicine, USA
Transcriptional Control of DC Development

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 5 of 6
Florent Ginhoux, Singapore Immunology Network, Singapore
Short Talk: Revisiting the Ontogeny of the Mononuclear Phagocyte System: Embryonic and Adult Hematopoietic Contributions

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 6 of 6
Richard A. Kroczek, Robert Koch-Institute, Germany
Short Talk: The Chemokine Receptor XCR1 Is a Lineage Marker for Cross-Presenting DCs

Monday, March 04 | 9:40AM - 10:00AM
Coffee Break
Room: Longs Peak Foyer


Monday, March 04 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Monday, March 04 | 12:15PM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Monday, March 04 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 1 of 10
* Bernard Malissen, Centre d'Immunologie de Marseille-Luminy, France

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 2 of 10
* Nir Hacohen, Massachusetts General Hospital, USA

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 3 of 10
Venetia Bigley, Newcastle University, UK
Dendritic Cells in Human Primary Immunodeficiencies: Insights into DC Biology

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 4 of 10
Herbert Strobl, Medical University Graz, Austria
Identification of the Receptor Tyrosine Kinase Axl as a Downstream Effector of TGF-beta1 during Langerhans Cell Differentiation and Epidermal Homeostasis

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 5 of 10
Romain F. Banchereau, Baylor Institute for Immunology Research, USA
A Modular Transcriptional Framework Characterizes Human Dendritic Cell Responses to Pathogens and Vaccines

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 6 of 10
Gaëlle Breton, Rockefeller University, USA
Gene Profiling of Dendritic Cell Subsets after in vivo Administration of TLR3 Agonist in Healthy Human Volunteers

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 7 of 10
Charlotte L. Scott, University of Ghent & VIB, Belgium
Conventional Dendritic Cell Precursors Give Rise to Four Distinct Subsets of Dendritic Cells in the Steady State Intestine

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 8 of 10
Laura Gutiérrez, Sanquin Research and Landsteiner Laboratory, Netherlands
What Does Gata1 Do to Dendritic Cells?

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 9 of 10
Alan D. Guerrero, NIDDK, National Institutes of Health, USA
IL-2 Inhibits Dendritic Cell Development by Acting on Precursors and Altering DC-Associated Transcription Factors

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 10 of 10
Evangelos Andreakos, Biomedical Research Foundation-Academy of Athens, Greece
IL-28A (IFN-lambda2) Modulates Lung DC Function to Promote Th1 Immune Skewing and Suppress Allergic Airway Disease

Monday, March 04 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Monday, March 04 | 5:00PM - 7:00PM
Transcriptional Control of DC Development and Function
Room: Grays Peak

Speaker 1 of 4
Hideki Ueno, Icahn School of Medicine at Mount Sinai, USA
Functional Specialization of Human DC Subsets

Monday, March 04 | 5:00PM - 7:00PM
Transcriptional Control of DC Development and Function
Room: Grays Peak

Speaker 2 of 4
Nir Hacohen, Massachusetts General Hospital, USA
Genes and Networks Underlying Dendritic Cell Activation

Monday, March 04 | 5:00PM - 7:00PM
Transcriptional Control of DC Development and Function
Room: Grays Peak

Speaker 3 of 4
* Bali Pulendran, Stanford University School of Medicine, USA
Systems Vaccinology: Enabling Rational Vaccine Design with Systems Biology

Monday, March 04 | 5:00PM - 7:00PM
Transcriptional Control of DC Development and Function
Room: Grays Peak

Speaker 4 of 4
Shalin H. Naik, Walter & Eliza Hall Institute, Australia
Short Talk: Single Hematopoietic Progenitor Tracing Reveals Dendritic Cells Are a Distinct Lineage

Monday, March 04 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys


Monday, March 04 | 7:30PM - 10:00PM
Poster Session 1
Room: Shavano/Torreys


Tuesday, March 05 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 1 of 7
* Bart N. Lambrecht, VIB, Ghent University, Belgium
Dendritic Cells and the Unfolded Protein Response

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 2 of 7
* Averil I. Ma, University of California, San Francisco, USA
Ubiquitination and DC Functions

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 3 of 7
Davor Frleta, Mt. Sinai Medical Center, USA
Short Talk: HIV-1 Infection-Induced Apoptotic Microparticles Inhibit Human Dendritic Cells via CD44

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 4 of 7
Pablo Vargas, Institut Curie, France
Short Talk: Developmental Regulation of Dendritic Cell Migration

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 5 of 7
Lesley Ann Smyth, King's College London, UK
Short Talk: Intercellular Transfer of Regulatory T Cell Specific MicroRNA to Dendritic Cells Leads to Modulation of Dendritic Cell Function

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 6 of 7
Diana Matheoud, Université de Montréal, Canada
Short Talk: Leishmania Inhibits Crosspresentation through the Cleavage of VAMP8

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 7 of 7
Marianne L. Boes, University Medical Centre, Netherlands
Short Talk: Potentiation of Cross-Presentation by Human Blood and Lymphoid Tissue BDCA-3+ Dendritic Cells

Tuesday, March 05 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Tuesday, March 05 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Tuesday, March 05 | 11:00AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Tuesday, March 05 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 1 of 10
* Nicolas Manel, Institut Curie, France

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 2 of 10
* Peter T. Lee, Immunity, Cell Press, USA

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 3 of 10
Yasuyuki Saito, Kobe University Graduate School of Medicine, Japan
Dendritic Cell Homeostasis Is Maintained by Non-Hematopoietic and T Cell-Produced Flt3-Ligand in Steady-State and during Antigen-Specific Immune Responses

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 4 of 10
Sonja I. Buschow, Nijmegen Centre for Molecular Life Sciences, Netherlands
The Human Dendritic Cell Phagosome Proteome: Novel Players and Implications for the Regulation of Receptor Mediation Phagocytosis

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 5 of 10
Cary D. Austin, Genentech, Inc., USA
Mice with Conditional Deletion of NF-kappaB–Inducing Kinase (NIK) in Dendritic Cells Show Defective CD40-Dependent Antigen Cross-Priming of CD8+ T Cells

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 6 of 10
Jeoung-Sook Shin, University of California, San Francisco, USA
Ubiquitin-Mediated MHCII Turnover Promotes Dendritic Cell Selection of Natural Regulatory T Cells

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 7 of 10
Zhe Wang, Purdue University, USA
Critical Role of Linear Ubiquitin Regulator SHARPIN in NF-kappaB Signaling and Induction of TH1 Cells by Dendritic Cells

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 8 of 10
Ilaria Tassi, Alector, USA
The NF-kappaB Regulator Bcl-3 Plays a Critical Role in the Initiation of Adaptive Immune Responses

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 9 of 10
Mitsuo Hashimoto, University of California, San Francisco, USA
The Role of alphanubeta8-Mediated Activation of TGF-beta by Fibroblasts in Directing Dendritic Cell Migration

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 10 of 10
Guy Shakhar, Weizmann Institute of Science, Israel
Dynamic Imaging Reveals Promiscuous Cross-Presentation of Blood-Borne Antigens to Naïve CD8+ T Cells in the Bone Marrow

Tuesday, March 05 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, March 05 | 5:00PM - 7:00PM
Molecular and Functional Aspects of DC Migration
Room: Grays Peak

Speaker 1 of 4
* Gwendalyn J. Randolph, Washington University, USA
Normal Dendritic Cell Mobilization to Lymph Nodes under Conditions of Severe Lymphatic Hypoplasia

Tuesday, March 05 | 5:00PM - 7:00PM
Molecular and Functional Aspects of DC Migration
Room: Grays Peak

Speaker 2 of 4
Reinhold Förster, Hannover Medical School, Germany
Lymph Node Homing of DCs, pDCs, and Activated T Cells via Afferent Lymphatics

Tuesday, March 05 | 5:00PM - 7:00PM
Molecular and Functional Aspects of DC Migration
Room: Grays Peak

Speaker 3 of 4
Michael Sixt, Institute of Science and Technology Austria, Austria
Cytoskeletal Dynamics of Dendritic Cells

Tuesday, March 05 | 5:00PM - 7:00PM
Molecular and Functional Aspects of DC Migration
Room: Grays Peak

Speaker 4 of 4
Stephanie C. Eisenbarth, Yale University, USA
Short Talk: NOD-Like Receptor NLRP10 Regulates Migration of CD11b-Positive Dendritic Cells

Tuesday, March 05 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys


Tuesday, March 05 | 7:30PM - 10:00PM
Poster Session 2
Room: Shavano/Torreys


Wednesday, March 06 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 1 of 5
Eicke Latz, University of Bonn, Germany
Inflammasome Activation in Macrophages and Dendritic Cells

Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 2 of 5
* Laurence Zitvogel, Institut Gustave Roussy, France
Gut Microbiota Influences T Cell-Dependent Anticancer Immunity during Chemotherapy

Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 3 of 5
Romina S. Goldszmid, NCI, National Institutes of Health, USA
Short Talk: Commensal Microbiota Modulates the Innate Response to Cancer Immunotherapy and Chemotherapy

Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 4 of 5
* Yong-Jun Liu, Sanofi, USA
Biochemical Characterization of Nucleic Acid Sensors in Dendritic Cells

Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 5 of 5
Nicolas Manel, Institut Curie, France
Short Talk: HIV Capsid Dissociates Cytosolic Sensing and Productive Infection in Dendritic Cells

Wednesday, March 06 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, March 06 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Wednesday, March 06 | 11:15AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Wednesday, March 06 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Wednesday, March 06 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, March 06 | 5:00PM - 7:00PM
Role of PDC in Immunity and Disease
Room: Grays Peak

Speaker 1 of 4
Brian D. Brown, Mount Sinai School of Medicine, USA
MicroRNA Control of DC Development

Wednesday, March 06 | 5:00PM - 7:00PM
Role of PDC in Immunity and Disease
Room: Grays Peak

Speaker 2 of 4
* Marco Colonna, Washington University School of Medicine, USA
pDC in Host Defense

Wednesday, March 06 | 5:00PM - 7:00PM
Role of PDC in Immunity and Disease
Room: Grays Peak

Speaker 3 of 4
Toshiaki Ohteki, Tokyo Medical and Dental University, Japan
New DC Progenitors with Prominent pDC Differentiation Potential

Wednesday, March 06 | 5:00PM - 7:00PM
Role of PDC in Immunity and Disease
Room: Grays Peak

Speaker 4 of 4
Miguel A. Sanjuan, Bristol-Myers Squibb Co., USA
Short Talk: LC3-Associated Phagocytosis Mediates IFN-alpha Secretion in Response to DNA-Immune Complexes

Wednesday, March 06 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys


Wednesday, March 06 | 7:30PM - 10:00PM
Poster Session 3
Room: Shavano/Torreys


Thursday, March 07 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 1 of 6
Matthew L. Albert, Genentech, Inc., USA
Influence of Cell Death on Tumor Immunity

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 2 of 6
* William R. Heath, University of Melbourne, Australia
Dendritic Cells, Receptors and Initiation of Immunity

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 3 of 6
* Steffen Jung, Weizmann Institute of Science, Israel
Critical Dendritic Cell / Macrophage Crosstalk in the Intestinal Lamina Propria

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 4 of 6
Hamida Hammad, Ghent University & VIB, Belgium
Role of Dendritic Cells in the Pathogenesis of Asthma

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 5 of 6
Carl Allen, Baylor College of Medicine, USA
Short Talk: BRAF-V600E Is Identified in Circulating Myelomonocytic Precursors in Patients with High-Risk Langerhans Cell Histiocytosis

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 6 of 6
Jesse Warren Williams, Washington University, USA
Short Talk: Interferon Regulatory Factor 4 (IRF4) in Dendritic Cells (DCs) Promotes Th2 Responses and Regulates IL-10 and IL-33 Production

Thursday, March 07 | 9:00AM - 9:20AM
Coffee Break
Room: Longs Peak Foyer


Thursday, March 07 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 1 of 10
* Florent Ginhoux, Singapore Immunology Network, Singapore

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 2 of 10
* Zoltan Fehervari, Nature Publishing Group, UK

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 3 of 10
Heidi A. Schreiber, Rockefeller University, USA
Comparing pre-DC and Monocyte-Derived Cell Heterogeneity and Function in Non-Lymphoid Organs

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 4 of 10
Wing-Hong Kwan, Mount Sinai School of Medicine, USA
Complement Proteins Produced by Dendritic Cells Control Effector T Cell Differentiation and Regulatory T Cell Function

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 5 of 10
Sotaro Ochiai, Malaghan Institute of Medical Research, New Zealand
TSLP-Dependent and Independent Induction of Th2 Responses via Dermal Dendritic Cells

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 6 of 10
Juliana Idoyaga, Rockefeller University, USA
Specialized Role of Migratory Dendritic Cells in Peripheral Tolerance Induction

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 7 of 10
Nir Yogev, University of Mainz, Germany
Dendritic Cells Control CNS Autoimmunity by Induction of Tregs through PD-L/PD-1 Interaction

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 8 of 10
Nathalie Bendriss-Vermare, Cancer Research Center of Lyon, France
Plasmacytoid Dendritic Cells Deficient in IFN-alpha Production Promote the Amplification of FOXP3+ Regulatory T Cells though ICOS/ICOS-L Interaction in Breast Cancer

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 9 of 10
Suryasarathi Dasgupta, Takeda California, Inc., USA
Critical Role of Plasmacytoid Dendritic Cells in Immunoregulation Initiated by a Commensal Microbial Polysaccharide

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 10 of 10
Teja Celhar, Singapore Immunology Network, Singapore
Enhanced RNA-Sensing in Dendritic Cells (DCs) Is Required for the Development of Severe Disease in SLE-Prone Mice

Thursday, March 07 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, March 07 | 5:00PM - 6:30PM
Harnessing DC Biology to Advance Disease Therapies
Room: Grays Peak

Speaker 1 of 4
* Ira Mellman, Genentech, Inc., USA

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