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Web Desc
Pulmonary Vascular Disease and Right Ventricular Dysfunction: Current Concepts and Future Therapies
Organizer(s): Georg Hansmann, Stephen L. Archer and Margaret R. MacLean
Date: September 10 - 15, 2012
Location: Portola Hotel & Spa, Monterey, CA, USA
Sponsored by Bayer USA Foundation
Summary of Meeting:
Pulmonary arterial hypertension (PAH) is characterized by progressive obliteration of pulmonary arterioles leading to increased pulmonary vascular resistance, right heart failure and death in 40-60% of PAH patients five years after diagnosis. Proliferation, migration and resistance to apoptosis of vascular cells, as well as proliferative-inflammatory responses mediated by blood and fat cells, contribute to disease development. Despite more than 15 published randomized controlled trials (RCT) that demonstrated moderate effectiveness in improving exercise capacity, the approved PH drugs have not led to a cure. Hence, basic science and translational research focusing on the discovery of novel pathways in pulmonary vascular disease and right ventricular dysfunction, new drug targets, development of novel therapeutic paradigms, cell-based and pharmacotherapies, and their translation into RCTs, is urgently needed. This Keystone Symposia meeting will gather basic and clinical researchers working in the field of pulmonary vascular disease and right ventricular dysfunction. The focus is on basic science with strong impact on 1) our understanding of this fatal disease and 2) discoveries with great potential to be translated into clinical practice in the near future. Late-breaking clinical studies on novel PAH therapies will also be presented.
Scholarship Deadline: June 7 2012
Discounted Abstract Deadline: June 7 2012
Abstract Deadline: June 21 2012
Discounted Registration Deadline: July 10 2012
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bayer USA Foundation
We gratefully acknowledge additional support for this conference from:

American Heart Association's Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation

American Heart Association's Council on Cardiovascular Disease in the Young
$1 - $2,499

Pulmonary Circulation / Pulmonary Vascular Research Institute

Pulmonary Hypertension Association
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Pulmonary Circulation / Pulmonary Vascular Research InstitutePulmonary Hypertension Association
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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