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Web Desc
B Cell Development and Function
joint with HIV Vaccines
Organizer(s): Max D. Cooper, Andrea Cerutti and Carola G. Vinuesa
Date: February 10 - 15, 2013
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Onyx Pharmaceuticals, Inc.
Summary of Meeting:
This meeting will provide an overview of the most recent advances in the biology of B cells. In addition to covering the function of B cells under steady-state conditions and infection, the meeting will provide an update on the alterations of B cells in autoimmunity, leukemia and lymphoma. The mechanisms by which B cells crosstalk with different components of the innate and adaptive immune systems and the contribution of distinct B cell subsets to systemic and mucosal immunity remain unclear, particularly in humans. This meeting has the following specific aims: 1) to define the factors involved in B cell lineage specification and reprogramming; 2) to elucidate the evolution and mechanisms of the processes underpinning antibody gene diversification; 3) to better understand the B cell pathways required for systemic and mucosal antibody responses against T cell-dependent and T cell-independent antigens; 4) to clarify the mechanisms by which antibodies provide protection against HIV; 5) to broaden our understanding of the molecular alterations associated with autoimmune and neoplastic B cell disorders; and 6) to provide an interactive forum to involve early stage investigators and highlight their discoveries. By addressing these problems, this meeting will not only generate new knowledge on the biology of B cells in health and disease states, but it will also provide a framework for investigators and clinicians to generate new ideas, initiate new collaborations, and eventually introduce changes in clinical practice. In addition, this meeting will provide a unique opportunity to “take a closer look” at B cells by linking experts in B cell biology with experts in stem cell biology, comparative immunology, molecular biology, and in vivo imaging. Additional opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on HIV Vaccines, which will share a keynote session and two plenary sessions with this meeting.
Scholarship Deadline: October 10 2012
Discounted Abstract Deadline: October 10 2012
Abstract Deadline: November 12 2012
Discounted Registration Deadline: December 10 2012
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Onyx Pharmaceuticals, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI104097-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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