This meeting took place in the past. For a complete list of the meetings for the upcoming/current season, see our meeting list or click on related meetings tab below to check for related meeting(s).
Web Desc
Tissue-Resident Memory T Cells
Organizer(s): Cornelia L. Trimble, Rachael A. Clark, Leo Lefrançois (in memoriam) and David Masopust
Date: January 12 - 16, 2014
Location: Snowbird Resort, Snowbird, UT, USA
Sponsored by BioLegend, Inc. Supported by an educational donation provided by Amgen.
Summary of Meeting:
Infections that are encountered through epithelial barrier tissues such as the skin, gut, lung and genitourinary tract generate a population of tissue-resident T cells that remain sessile long-term in the affected tissue, and are protective against re-infection. Indeed, most effector memory T cells reside in non-sterile barrier epithelial tissues, as opposed to the circulation. While tissue-resident T cells play a critical role in defending against infections and cancer, aberrant activation of these cells gives rise to inflammatory and autoimmune conditions, including psoriasis, multiple sclerosis and inflammatory bowel disease. Tissue-resident T cells are not simply T cells in an unexpected location; these cells have many phenotypic and functional differences that distinguish them from circulating T cells. This conference will bring together basic and translational immunologists to discuss tissue-localized mechanisms of immune cell recruitment, retention, activation and homeostasis. The major objectives will be to: 1) Explore the roles that tissue immune cells play in immune surveillance, including recall responses to infectious pathogens, and mechanisms of dysregulation leading to autoimmune disease; 2) Examine the mechanisms by which immune responses can be shaped by the local tissue microbiome; 3) Investigate the mechanisms by which immune responses can be subverted by chronic infections or early neoplastic lesions; and 4) Discuss the rationale for immunotherapeutic strategies targeting specific tissue sites. A better understanding of the biology of tissue-resident T cells will inform vaccination strategies for both infections and cancer, as well as novel therapies for inflammatory and autoimmune diseases.
Scholarship Deadline: October 3 2013
Discounted Abstract Deadline: October 3 2013
Abstract Deadline: October 28 2013
Discounted Registration Deadline: November 13 2013
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Educational donation provided by Amgen.BioLegend, Inc.
We gratefully acknowledge additional support for this conference from:
Mucosal Immunology Studies Team (MIST), in memory of Dr. Leo LeFrancois
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI109814-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

No content found

No content found

No content found

No content found