Plant Signaling: Dynamic Properties Organizer(s): Ottoline Leyser, Junko Kyozuka and Pamela C. Ronald Date: February 05 - 10, 2014 Location: Beaver Run Resort, Breckenridge, CO, USAIn recent years, rapid progress has been made in elucidating the molecular events underlying perception of extracellular signals and their transduction to regulate specific responses. These advances in understanding make it possible to consider the emergent behavior of signaling cascades. In each signaling system, the configuration and dynamics of the underlying molecular interactions deliver specific properties linking the signal to its response. For example there could be a graded response to the level of signal or a tight threshold below which there is no response, and above which there is a maximal response. It is these higher order properties that are functionally important for the success of the organism, and therefore they are the level at which natural selection has acted to shape each signaling system. It is now becoming possible to investigate these higher order properties and to understand how apparently different molecular level events can nonetheless produce signaling systems with similar properties. The incorporation of mathematical and computational modeling, and the adoption synthetic biology approaches are becoming important tools in this endeavor. To capture this exciting new synthesis, we propose a symposium focusing on the relationship between molecular level events and their higher order behavior, comparing the properties of signaling systems in diverse species, including non-plant examples. The symposium will be structured around common signaling features, such as switching between on and off states, the control of specificity, robustness in an unstable environment, and modulation of the sensitivity of the system by its activity or by external factors. Scholarship Deadline: October 15 2013 Discounted Abstract Deadline: October 15 2013 Abstract Deadline: November 7 2013 Discounted Registration Deadline: December 5 2013 We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Amgen
$1 - $2,499 American Society of Plant Biologists We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:   We gratefully acknowledge the generous grant for this conference provided by: National Science Foundation (NSF)Grant No. MCB-1348958 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the National Science Foundation; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. |