Long Noncoding RNAs: Marching toward Mechanism Organizer(s): Thomas R. Cech, Edith Heard and Ronald R. Breaker Date: February 27 - March 04, 2014 Location: Eldorado Hotel & Spa, Santa Fe, NM, USAMuch of the mammalian genome is transcribed into long non-coding RNAs, but their biological roles -- such as transcriptional regulation via recruitment of histone-modifying enzymes – are only beginning to be discovered. At the same time, bacterial non-coding RNAs are being found to function as small-molecule-sensing riboswitches and as elements of the CRISPR defense system. For all of these biological systems, a key remaining problem is to understand the detailed mechanism of action. Listing and comparing all of the long ncRNAs, riboswitches, and CRISPR elements genome-wide and among species is useful, but how does the RNA function in each of these systems? The goal of this Keystone Symposium is to stimulate conversations between scientists who work on these very diverse RNA systems, so they can share conceptual frameworks and experimental techniques. This goal will be accomplished by convening an exceptional group of academic and industrial scientists and students to share their insights. Scholarship Deadline: October 29 2013 Discounted Abstract Deadline: October 29 2013 Abstract Deadline: December 4 2013 Discounted Registration Deadline: January 7 2014 We gratefully acknowledge additional support for this conference from:    RaNA Therapeutics We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
RaNA Therapeutics
We gratefully acknowledge the generous grant for this conference provided by: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Grant No. 1R13HD078065-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. |