The Ins and Outs of Viral Infection: Entry, Assembly, Exit and Spread
Organizer(s): Karla Kirkegaard, Mavis Agbandje-McKenna and Eric O. FreedDate: March 30 - April 04, 2014
Location: Beaver Run Resort, Breckenridge, CO, USA
Viruses can enter cells by mechanisms such as the classic virus-receptor interactions, cell-cell fusion and newly observed pathways that are currently being investigated. Similarly, viral exit from infected cells can follow the paradigms of cell lysis or viral budding, but new mechanisms such as unconventional secretion and exosome formation are emerging. Viruses in the process of entering or exiting cells should be especially vulnerable to antivirals because of their accessibility and because the formation of oligomeric structures that mix drug-susceptible and drug-resistant capsids can suppress the emergence of drug-resistant viruses. However, these steps are more difficult to target biochemically due to the lack of readily assayed enzymatic activity. In this meeting, we will bring together structural biologists, geneticists, cell biologists and mathematic modeling to address the mechanisms and consequences of the different modes of viral travel.
Scholarship Deadline: December 2 2013
Discounted Abstract Deadline: December 2 2013
Abstract Deadline: January 7 2014
Discounted Registration Deadline: January 29 2014
We gratefully acknowledge the generous grant for this conference provided by:National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI109804-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.