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Web Desc
Autophagy: Fundamentals to Disease
Organizer(s): Christina H. Eng, Daniel J. Klionsky, Guido Kroemer and Li Yu
Date: May 23 - 28, 2014
Location: Hyatt Regency Austin, Austin, TX, USA
Sponsored by AbbVie Inc., Cell Research and Shire Human Genetic Therapies
Summary of Meeting:
Autophagy is a fundamental cellular process that orchestrates the degradation of proteins, lipids and organelles during both basal and cellular or environmental stress conditions. Once thought to occur only during times of nutrient limitation, autophagy clearly plays major roles in both developmental and pathological situations. As the importance of autophagy in a variety of diseases is emerging, an in-depth knowledge of primary and alternative autophagic pathways is required to fully understand and effectively modulate it. The forefront of autophagy research will be highlighted at this meeting, from basic mechanistic insights and signaling to the role autophagy plays in multiple disease areas and prospects for therapeutic targeting. Key areas of discussion will include the source of the autophagosomal membrane, new mechanistic insights into both macroautophagy and mitophagy, and the critical roles of autophagy in normal and disease situations such as cancer, neurodegenerative diseases, Crohn’s disease, lysosomal storage diseases, cardiomyopathy and aging. Examining the role of autophagy in disease will enable us to understand in contexts in which modulation of autophagy may be beneficial, and identifying the core processes that control autophagy will enable us to identify tools to modulate the pathway. This meeting will bring together a variety of investigators exploring different facets of autophagy, and their interactions will expand our knowledge of fundamental autophagic mechanisms in different contexts and their critical functions in physiological and pathological settings.
Scholarship Deadline: January 23 2014
Discounted Abstract Deadline: January 23 2014
Abstract Deadline: February 27 2014
Discounted Registration Deadline: March 24 2014
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
AbbVie Inc.Cell ResearchShire Human Genetic Therapies
We gratefully acknowledge additional support for this conference from:
Cell Signaling Technology, Inc.Promega Corporation
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Novartis Pharma AG

Pfizer Oncology
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
EMBO (European Molecular Biology Organization)
We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA183034-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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