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Web Desc
The Brain: Adaptation and Maladaptation in Chronic Pain
Organizer(s): Frank Porreca, David Borsook and David W. Dodick
Date: June 15 - 20, 2014
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Regeneron Pharmaceuticals, Inc.
Summary of Meeting:
SIGNIFICANCE: The Institutes of Medicine indicate that pain affects more than 100 million Americans and costs more than an estimated $540-630 billion, a number predicted to only increase as our population ages and is influenced by lifestyle. We have few effective treatments for migraine or chronic pain. GOALS: Understanding the complexities of brain circuits involved in pain and migraine headache has been a major challenge in neurobiology that has limited the discovery of new therapies. For decades, the pain and headache communities have separately focused on peripheral mechanisms. INNOVATION: This conference brings together the world’s leading experts in brain systems neuroscience to highlight the advances in understanding brain systems relevant to the neurobiology of migraine and chronic pain. We wish to explore neurobiology of pain and headache together with contributions and attendance from both communities. APPROACH: A conversation of a number of new technologies has opened new opportunities to better understand the neural networks involved in the emotional, cognitive and sensory components of pain and consequent suffering. New technologies have opened doors to revolutionize our concepts of the impact of pain on the brain. OPPORTUNITY: Bringing together scientists from different disciplines related to, but not exclusively connected to pain and headache as a key to integration and bridging of disciplines and advancement of knowledge in these areas of clinical need. Accumulating functional and imaging data implicate headache and chronic pains as diseases of the brain – either primarily or secondarily as a consequence of peripheral damage. OUTCOME: We are at an exciting moment in the neurosciences where new understanding of brain function promises to change paradigms for drug discovery for neurological disorders. The promise is great, and the next decade of brain sciences research will redefine disease states, including predictive and personalized medicine, allow imaging the brain during pain and its relief by treatments in the individual patients suffering from pain.
Scholarship Deadline: February 13 2014
Discounted Abstract Deadline: February 13 2014
Abstract Deadline: March 13 2014
Discounted Registration Deadline: April 30 2014
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Regeneron Pharmaceuticals, Inc.
We gratefully acknowledge additional support for this conference from:
Educational grant from Lilly
$2,500 - $9,999

SAGE: Cephalalgia, published by SAGE on behalf of the International Headache Society
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

SAGE: Cephalalgia
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Neurological Disorders and Stroke (NINDS)
Grant No. 1R13NS087854-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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