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Alzheimer's Disease - From Fundamental Insights to Light at the End of the Translational Tunnel
joint with Parkinson's Disease: Genetics, Mechanisms and Therapeutics
Organizer(s): John Q. Trojanowski, Charles F. Albright and Hui Zheng
Date: March 02 - 07, 2014
Location: Keystone Resort, Keystone, CO, USA
Sponsored by AstraZeneca, Genentech, Inc., Pfizer Inc., Roche and Takeda Pharmaceutical Company Limited
Summary of Meeting:
Alzheimer’s disease (AD), Parkinson’s disease (PD) and related neurodegenerative disorders are becoming increasingly more prevalent in the United States and globally due to the longevity revolution. The consequences of these diseases are grave, both for individuals and the global community, prompting concerns that rising healthcare costs have the potential to result in deleterious effects on national economies that could spell disaster unless disease-modifying therapies are discovered very soon. Fortunately, remarkable progress has been made toward elucidating mechanisms of AD since the discovery of the Abeta peptide in 1984, which launched the molecular era of AD research. That, coupled with the demonstration that tau is a building block of AD tangles in 1991, led to the understanding that AD, PD and most other neurodegenerative disorders are protein misfolding diseases, which has led to further clarity about mechanisms underlying AD. This has culminated in the identification of new targets for disease-modifying therapies as well as biomarkers for AD. Most recently, provocative data have emerged suggesting that the progression of AD may be due to the cell-to-cell spread of pathological species of tau and Abeta, thereby ushering in exciting new opportunities to arrest AD progression with immune therapies. Thus, the purpose of this meeting, which will be held in concert with a parallel meeting on “Parkinson’s Disease: Genetics, Mechanisms and Therapeutics,” is to explore these fundamental insights into mechanisms of AD and the opportunities they provide to translate this knowledge into meaningful interventions for AD.
Scholarship Deadline: November 5 2013
Discounted Abstract Deadline: November 5 2013
Abstract Deadline: December 5 2013
Discounted Registration Deadline: January 8 2014
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
AstraZenecaGenentech, Inc.Pfizer Inc.RocheTakeda Pharmaceutical Company Limited
We gratefully acknowledge additional support for this conference from:
Alzheimer
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Bristol-Myers Squibb Company

Merck
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Neurological Disorders and Stroke (NINDS)
Grant No. 1R13NS084618-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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