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Tuesday, October 28 | 4:00PM - 8:00PM
Arrival and Registration
Room: Imperial Ballroom Foyer


Tuesday, October 28 | 6:00PM - 7:00PM
Welcome Mixer
Room: Imperial Ballroom Terrace


Wednesday, October 29 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Wednesday, October 29 | 8:30AM - 9:30AM
Keynote Address
Room: Imperial Ballroom

Speaker 1 of 2
* Douglas R. Green, St. Jude Children's Research Hospital, USA

Wednesday, October 29 | 8:30AM - 9:30AM
Keynote Address
Room: Imperial Ballroom

Speaker 2 of 2
Vishva M. Dixit, Genentech, Inc., USA
Interplay between NOD Sensors that Mediated Pyroptosis

Wednesday, October 29 | 9:30AM - 12:00PM
Cell Death Signaling I
Room: Imperial Ballroom

Speaker 1 of 5
* Seamus J. Martin, Trinity College Dublin, Ireland

Wednesday, October 29 | 9:30AM - 12:00PM
Cell Death Signaling I
Room: Imperial Ballroom

Speaker 2 of 5
Guy S. Salvesen, Sanford-Burnham Medical Research Institute, USA
A Toolbox of Highly Selective Caspase Chemical Reagents

Wednesday, October 29 | 9:30AM - 12:00PM
Cell Death Signaling I
Room: Imperial Ballroom

Speaker 3 of 5
Mohanish Deshmukh, University of North Carolina at Chapel Hill, USA
How Cells Evade Apoptosis: From Neurons to Cancer

Wednesday, October 29 | 9:30AM - 12:00PM
Cell Death Signaling I
Room: Imperial Ballroom

Speaker 4 of 5
Stefan J. Riedl, Sanford-Burnham Medical Research Institute, USA
Short Talk: Structure and Mechanism: Death Domains in the Regulation of Immunity and Cancer

Wednesday, October 29 | 9:30AM - 12:00PM
Cell Death Signaling I
Room: Imperial Ballroom

Speaker 5 of 5
Douglas R. Green, St. Jude Children's Research Hospital, USA
How Cells Survive: Single Cell Analysis Reveals Properties of Non-Genetic Apoptosis Resistance

Wednesday, October 29 | 10:10AM - 10:30AM
Coffee Break
Room: Imperial Ballroom Terrace


Wednesday, October 29 | 12:00PM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Wednesday, October 29 | 12:00PM - 2:30PM
On Own for Lunch


Wednesday, October 29 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 1 of 9
* David W. Andrews, Sunnybrook Research Institute, Canada

Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 2 of 9
Peter Huebener, University Hospital Hamburg-Eppendorf, Germany
HMGB1 Links Chronic Injury and Cancer in the Liver

Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 3 of 9
Keehoon Jung, Harvard Medical School, Massachusetts General Hospital, USA
Targeting the Immune Microenvironment to Improve Colorectal Cancer Treatment

Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 4 of 9
Nga Lam, Walter and Eliza Hall Institute, Australia
Understanding the Role of Bcl-G in Cell Death Signaling And Colorectal Cancer

Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 5 of 9
Yannick Böge, University Hospital Zürich, Switzerland
An Apoptosis-Driven Pathway to Hepatocarcinogenesis

Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 6 of 9
Hetal Brahmbhatt, McMaster University, Canada
Identification and Characterization of Small Molecules that Enhance the Pro-Apoptotic Activity of Bax

Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 7 of 9
Stephen E. Girardin, University of Toronto, Canada
The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis

Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 8 of 9
Gabriel Ichim, UK
Limited Mitochondrial Permeabilisation Causes DNA-Damage and Genomic Instability in the Absence of Cell Death

Wednesday, October 29 | 2:30PM - 4:30PM
Workshop 1: Cancer
Room: Imperial Ballroom

Speaker 9 of 9
Fabien Llambi, St. Jude Children's Research Hospital, USA
BOK is a Pro-Apoptotic Effector Protein Regulated by the Ubiquitin-Proteasome System

Wednesday, October 29 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Wednesday, October 29 | 5:00PM - 7:00PM
Cell Death Signaling II
Room: Imperial Ballroom

Speaker 1 of 5
* Shigekazu Nagata, IFReC, Osaka University, Japan

Wednesday, October 29 | 5:00PM - 7:00PM
Cell Death Signaling II
Room: Imperial Ballroom

Speaker 2 of 5
Marion MacFarlane, MRC Toxicology Unit, UK
c-FLIP-Mediated Regulation of Caspase-8 DED Chain Assembly Determines Cell Fate

Wednesday, October 29 | 5:00PM - 7:00PM
Cell Death Signaling II
Room: Imperial Ballroom

Speaker 3 of 5
Peter Vandenabeele, VIB, Ghent University, Belgium
Necroptosis versus Apoptosis

Wednesday, October 29 | 5:00PM - 7:00PM
Cell Death Signaling II
Room: Imperial Ballroom

Speaker 4 of 5
Francis Ka-Ming Chan, Duke University, USA
Playing with Fire: Necroptosis-Dependent and Independent Roles of RIPK3 in Inflammation

Wednesday, October 29 | 5:00PM - 7:00PM
Cell Death Signaling II
Room: Imperial Ballroom

Speaker 5 of 5
Silvia Alvarez-Diaz, Walter and Eliza Hall Institute, Australia
Short Talk: MLKL Plays a Critical Role Inducing Necroptosis within a Physiological Context

Wednesday, October 29 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace


Wednesday, October 29 | 7:30PM - 10:00PM
Poster Session 1
Room: Imperial Ballroom


Thursday, October 30 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Thursday, October 30 | 8:30AM - 11:45AM
Cell Death and Cancer I
Room: Imperial Ballroom

Speaker 1 of 7
* Karen H. Vousden, Francis Crick Institute, UK

Thursday, October 30 | 8:30AM - 11:45AM
Cell Death and Cancer I
Room: Imperial Ballroom

Speaker 2 of 7
Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia
How Does p53 Prevent Cancer?

Thursday, October 30 | 8:30AM - 11:45AM
Cell Death and Cancer I
Room: Imperial Ballroom

Speaker 3 of 7
David W. Andrews, Sunnybrook Research Institute, Canada
Regulation of Mitochondrial Membrane Permeabilization by Bcl-2 Family Proteins

Thursday, October 30 | 8:30AM - 11:45AM
Cell Death and Cancer I
Room: Imperial Ballroom

Speaker 4 of 7
Axel Witt, University Hospital Cologne, Germany
Short Talk: IAP Antagonization Induces Inflammatory Destruction of Vasculature Endothelium and Inhibits Tumor Growth

Thursday, October 30 | 8:30AM - 11:45AM
Cell Death and Cancer I
Room: Imperial Ballroom

Speaker 5 of 7
Gerry Melino, University of Rome ‘Tor Vergata’, Italy
Control of Cell Fate by miRNA

Thursday, October 30 | 8:30AM - 11:45AM
Cell Death and Cancer I
Room: Imperial Ballroom

Speaker 6 of 7
Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA
Cellular Cooperation in Normal Tissues and Tumors

Thursday, October 30 | 8:30AM - 11:45AM
Cell Death and Cancer I
Room: Imperial Ballroom

Speaker 7 of 7
Stephen W. Fesik, Vanderbilt University School of Medicine, USA
Short Talk: Mcl-1 Inhibitors for the Treatment of TNBC and Other Cancers

Thursday, October 30 | 9:50AM - 10:10AM
Coffee Break
Room: Imperial Ballroom Terrace


Thursday, October 30 | 11:45AM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Thursday, October 30 | 11:45AM - 2:30PM
On Own for Lunch


Thursday, October 30 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 1 of 9
* Petr Broz, University of Lausanne, Switzerland

Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 2 of 9
* Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA

Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 3 of 9
Goutam Gupta, Los Alamos National Laboratory, USA
Preventing Host Cell Death by Engineering of Novel Innate Immune Defense

Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 4 of 9
Luciana Paroneto Medina, Institute of Biomedical Sciences, University of São Paulo, Brazil
PGE2 as a Regulator of Experimental Autoimmune Encephalomyelitis (EAE)

Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 5 of 9
Maria Andree, University of Cologne, Germany
BID-Dependent Release of Mitochondrial SMAC Dampens XIAP-Mediated Immunity Against Shigella

Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 6 of 9
Dmitry M. Shayakhmetov, Emory University, USA
The Identification of the Novel Physiologically-Regulated Necrotic Cell Death Pathway Mediated by the Interferon-Regulatory Factor 3 (IRF3)

Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 7 of 9
Eugenio D. Hottz, Oswaldo Cruz Foundation, Brazil
Activation of Inflammasome and Cell Death Pathways in Platelets Modulate Inflammatory Responses in Dengue

Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 8 of 9
Bernardo S. Franklin, University of Bonn, Germany
The Extracellular Functions of the Inflammasomes

Thursday, October 30 | 2:30PM - 4:30PM
Workshop 2: Host Defense
Room: Imperial Ballroom

Speaker 9 of 9
Jennifer Martinez, NIEHS, National Institutes of Health, USA
LC3-Associated Phagocytosis as a Critical Regulator of Inflammation

Thursday, October 30 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Thursday, October 30 | 5:00PM - 7:00PM
Cell Death and Cancer II
Room: Imperial Ballroom

Speaker 1 of 5
* Simone Fulda, University Hospital Frankfurt, Germany

Thursday, October 30 | 5:00PM - 7:00PM
Cell Death and Cancer II
Room: Imperial Ballroom

Speaker 2 of 5
Gerard I. Evan, University of Cambridge, UK
Killing Cancers without Killing Normal Tissues

Thursday, October 30 | 5:00PM - 7:00PM
Cell Death and Cancer II
Room: Imperial Ballroom

Speaker 3 of 5
Karen H. Vousden, Francis Crick Institute, UK
Metabolic Control of Cancer Cell Fate Decisions

Thursday, October 30 | 5:00PM - 7:00PM
Cell Death and Cancer II
Room: Imperial Ballroom

Speaker 4 of 5
Anthony G. Letai, Dana-Farber Cancer Institute, USA
Kicking Cancer Right in the Mitochondria

Thursday, October 30 | 5:00PM - 7:00PM
Cell Death and Cancer II
Room: Imperial Ballroom

Speaker 5 of 5
Andreas Bergmann, University of Massachusetts Medical School, USA
Short Talk: Autophagy Regulates Tissue Overgrowth in a Context-Dependent Manner

Thursday, October 30 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace


Thursday, October 30 | 7:30PM - 10:00PM
Poster Session 2
Room: Imperial Ballroom


Friday, October 31 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Friday, October 31 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 1 of 6
* Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA

Friday, October 31 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 2 of 6
Petr Broz, University of Lausanne, Switzerland
Caspase-11 Activation Requires Lysis of Pathogen-Containing Vacuoles by IFN-Induced GTPases

Friday, October 31 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 3 of 6
Domagoj Vucic, Genentech, Inc., USA
IAP Proteins Regulate the Formation of Necrosome and Inflammasome Complexes

Friday, October 31 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 4 of 6
Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Inflammasome Control of Disease

Friday, October 31 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 5 of 6
Karina R. Bortoluci, Federal University of São Paulo, Brazil
Lysosomal Pathway Induced by Cytosolic Flagellin in Cell Death and Immunity

Friday, October 31 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 6 of 6
Igor E. Brodsky, University of Pennsylvania, USA
Short Talk: RIPK1 and Caspase-8 Catalytic Activity Mediate Caspase-1 Activation in Response to Pathogen Blockade of Innate Immune Signaling

Friday, October 31 | 9:50AM - 10:10AM
Coffee Break
Room: Imperial Ballroom Terrace


Friday, October 31 | 11:30AM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Friday, October 31 | 11:30AM - 5:00PM
On Own for Lunch


Friday, October 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Friday, October 31 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Friday, October 31 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 1 of 5
* Eric H. Baehrecke, University of Massachusetts Medical School, USA

Friday, October 31 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 2 of 5
Janelle S. Ayres, The Salk Institute for Biological Studies, USA
Microbiota Control of Infection and Inflammation Induced Pathology

Friday, October 31 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 3 of 5
Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil
Short Talk: Novel Role for Galectin-1 in CTL Killing

Friday, October 31 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 4 of 5
Seamus J. Martin, Trinity College Dublin, Ireland
Cell Death and Inflammation: Revisiting the Danger Model


Friday, October 31 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 5 of 5
Avi Ashkenazi, Genentech, Inc., USA
Opposing UPR Signals Converge on DR5 to Control Apoptosis

Friday, October 31 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace


Friday, October 31 | 7:30PM - 10:00PM
Poster Session 3
Room: Imperial Ballroom


Saturday, November 01 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Saturday, November 01 | 8:30AM - 11:45AM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 1 of 7
* Peter Vandenabeele, VIB, Ghent University, Belgium

Saturday, November 01 | 8:30AM - 11:45AM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 2 of 7
Shigekazu Nagata, IFReC, Osaka University, Japan
Exposure of Phosphatidylserine during Apoptosis

Saturday, November 01 | 8:30AM - 11:45AM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 3 of 7
Kim Newton, Genentech, Inc., USA
Necroptosis Signaling and Inflammation

Saturday, November 01 | 8:30AM - 11:45AM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 4 of 7
Andrew Oberst, University of Washington, USA
Short Talk: Inflammatory and Immune Responses to Apoptosis and Necroptosis

Saturday, November 01 | 8:30AM - 11:45AM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 5 of 7
Will Wood, University of Edinburgh, UK
Signal Prioritization: Recognizing Death and Damage in vivo

Saturday, November 01 | 8:30AM - 11:45AM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 6 of 7
Eric H. Baehrecke, University of Massachusetts Medical School, USA
Inflammatory Signaling, Autophagy and Dying Cell Clearance

Saturday, November 01 | 8:30AM - 11:45AM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 7 of 7
Linda Julian, Beatson Institute for Cancer Research, UK
Short Talk: Apoptotic Blebbing in Tissue Homeostasis and Cancer

Saturday, November 01 | 9:50AM - 10:10AM
Coffee Break
Room: Imperial Ballroom Terrace


Saturday, November 01 | 11:45AM - 5:00PM
On Own for Lunch


Saturday, November 01 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Saturday, November 01 | 5:00PM - 6:15PM
Cell Death Therapies
Room: Imperial Ballroom

Speaker 1 of 3
* Kim Newton, Genentech, Inc., USA

Saturday, November 01 | 5:00PM - 6:15PM
Cell Death Therapies
Room: Imperial Ballroom

Speaker 2 of 3
Simone Fulda, University Hospital Frankfurt, Germany
Novel Opportunities to Target IAP Proteins for Cancer Therapy

Saturday, November 01 | 5:00PM - 6:15PM
Cell Death Therapies
Room: Imperial Ballroom

Speaker 3 of 3
David Ching Huang, Walter and Eliza Hall Institute of Medical Research, Australia
Therapeutically Targeting the Bcl-2-Regulated Cell Survival Pathway

Saturday, November 01 | 6:15PM - 7:15PM
Closing Keynote Address
Room: Imperial Ballroom

Speaker 1 of 2
* Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil

Saturday, November 01 | 6:15PM - 7:15PM
Closing Keynote Address
Room: Imperial Ballroom

Speaker 2 of 2
Scott W. Lowe, Memorial Sloan Kettering Cancer Center, USA
Tumor Suppressor and Tumor Maintenance Genes

Saturday, November 01 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Imperial Ballroom


Saturday, November 01 | 8:00PM - 11:00PM
Entertainment
Room: Imperial Ballroom


Saturday, November 01 | 8:00PM - 11:00PM
Cash Bar
Room: Imperial Ballroom


Sunday, November 02 | 10:25AM - 10:25AM
Departure


*Session Chair.

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