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Web Desc
Cell Biology of the Heart: Beyond the Myocyte-Centric View
joint with Heart Disease and Regeneration: Insights from Development
Organizer(s): Peter Kohl, Robert G. Gourdie and Stefanie Dimmeler
Date: March 01 - 06, 2015
Location: Copper Mountain Resort, Copper Mountain, CO, USA
Supported by the Directors' Fund
Summary of Meeting:
The heart is a muscle, and as such, much of the basic and applied research into cardiac structure and function has focused on cardiac myocytes. However, the majority of heart cells are non-myocytes. Prominent examples include cells comprising the coronary vasculature, fat, connective tissue (e.g., fibroblasts), nerves and immune cells. It has become increasingly clear that these cells are not merely bystanders of myocyte function, but active participants with important signaling roles that contribute to cardiac development, cell differentiation and function of the healthy and diseased heart. This Keystone Symposia meeting is unique, in that, for the first time, it brings together internationally-leading experts in the field of non-myocyte contributions to cardiac structure and function. It aims to address: 1) Roles of non-myocytes for cardiac cell fate determination and development; 2) Mechanisms of non-myocyte – myocyte signaling interactions; 3) Effects of these interactions in normal and diseased heart; and 4) Relevance of non-myocytes as targets for therapeutic interventions. Participants should leave this meeting with a more holistic understanding of the heart as a multi-cellular organ, and a broadened horizon to support their individual research. This is the first high-level symposium with an explicit focus on reviewing the current state of a new frontier of cardiac cell biology: non-myocyte roles in the development, regulation and adaptation of cardiac performance. The symposium should contribute to a paradigm shift that is taking place in the field, driven by the appreciation that a myocyte-centric view of the heart will always be limited in its ability to deliver the mechanistic understanding of cardiac structure and function that is required for improved predictive and therapeutic action.
Scholarship Deadline: November 4 2014
Discounted Abstract Deadline: November 4 2014
Abstract Deadline: December 3 2014
Discounted Registration Deadline: January 6 2015
We gratefully acknowledge additional support for this conference from:

American Heart Association's Councils on Basic CV Sciences, CV Disease in the Young, and Functional Genomics and Translational Biology
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

NeoStem, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Heart, Lung, and Blood Institute (NHLBI)
Grant No. 1R13HL126405-01
Funding for this conference was made possible (in part) by 1R13HL126405-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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