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Sunday, January 10 | 4:00PM - 8:00PM
Arrival and Registration
Room: Lower Atrium


Sunday, January 10 | 6:00PM - 8:00PM
Welcome Mixer
Room: Jefferson
No registration fees are used to fund alcohol served at this function.

Monday, January 11 | 7:00AM - 8:00AM
Breakfast
Room: Gallatin


Monday, January 11 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Jefferson/Madison

Speaker 1 of 2
* Ronald N. Germain, NIAID, National Institutes of Health, USA

Monday, January 11 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Jefferson/Madison

Speaker 2 of 2
Nir Hacohen, Massachusetts General Hospital, USA
Genes, Networks and Variations of the Immune Response

Monday, January 11 | 9:00AM - 11:00AM
Immunoreceptor Signaling I: Receptors and Pathways
Room: Jefferson/Madison

Speaker 1 of 4
* Grégoire Altan-Bonnet, NCI, National Institutes of Health, USA

Monday, January 11 | 9:00AM - 11:00AM
Immunoreceptor Signaling I: Receptors and Pathways
Room: Jefferson/Madison

Speaker 2 of 4
Smita Krishnaswamy, Yale School of Medicine, USA
Tracking the Impact of Immunotherapy Across the Phenotypic Landscape

Monday, January 11 | 9:00AM - 11:00AM
Immunoreceptor Signaling I: Receptors and Pathways
Room: Jefferson/Madison

Speaker 3 of 4
Suzanne Gaudet, Dana-Farber Cancer Institute/Harvard Medical School, USA
NF-kappaB Signaling Dynamics and the Control of Transcription and Cell Fate

Monday, January 11 | 9:00AM - 11:00AM
Immunoreceptor Signaling I: Receptors and Pathways
Room: Jefferson/Madison

Speaker 4 of 4
Bridget S. Wilson, University of New Mexico Health Science Center, USA
Short Talk: Dynamic Interactions of Pre-BCR Homodimers Provide Finely-Tuned Tonic Signals for Survival

Monday, January 11 | 9:40AM - 10:00AM
Coffee Break
Room: Lower Atrium


Monday, January 11 | 11:00AM - 1:00PM
Poster Setup
Room: Gallatin


Monday, January 11 | 11:00AM - 2:30PM
On Own for Lunch


Monday, January 11 | 1:00PM - 10:00PM
Poster Viewing
Room: Gallatin


Monday, January 11 | 1:00PM - 2:00PM
Publishing Forum

Speaker 1 of 4
* Angela Colmone, Science Immunology, USA

Monday, January 11 | 1:00PM - 2:00PM
Publishing Forum

Speaker 2 of 4
* Craig Mak, Cell Press, USA

Monday, January 11 | 1:00PM - 2:00PM
Publishing Forum

Speaker 3 of 4
* Thomas Lemberger, Molecular Systems Biology, Germany

Monday, January 11 | 1:00PM - 2:00PM
Publishing Forum

Speaker 4 of 4
* Corinne Williams, Journal of Clinical Investigation, JCI Insight, USA

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: Signaling
Room: Jefferson/Madison

Speaker 1 of 7
Mary H. Young, Celgene, USA
T Cell Receptor Signaling and Toll-Like Receptor Signaling Converge to Amplify T Cell Responses

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: Signaling
Room: Jefferson/Madison

Speaker 2 of 7
Arnon Arazi, Broad Institute, USA
Th17 Differentiation is an Emergent Collective Behavior, Driven by Cellular Heterogeneity

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: Signaling
Room: Jefferson/Madison

Speaker 3 of 7
* Rachel A. Gottschalk, NIAID, National Institutes of Health, USA
Contextual Control of TLR-Induced Responses by Divergent Signaling Thresholds

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: Signaling
Room: Jefferson/Madison

Speaker 4 of 7
Michael J.T. Stubbington, European Bioinformatics Institute, UK
Simultaneously Inferring T Cell Fate and Clonality from Single Cell Transcriptomes

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: Signaling
Room: Jefferson/Madison

Speaker 5 of 7
Wenji Ma, Columbia University, USA
Single Cell and Bulk Transcriptome Analysis Reveals Differentiation Mechanism of Human Dendritic Cell

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: Signaling
Room: Jefferson/Madison

Speaker 6 of 7
Ricardo Noel Ramirez, University of California, Irvine, USA
High-Resolution Epigenomic Analysis of Human Myeloid Differentiation Reveals Temporal and Cell-Specific Patterns of the Immune Regulatory Network

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: Signaling
Room: Jefferson/Madison

Speaker 7 of 7
Miri Adler, Weizmann Institute of Science, Israel
Cell Circuits for Tissue Homeostasis

Monday, January 11 | 4:30PM - 5:00PM
Coffee Available
Room: Lower Atrium


Monday, January 11 | 5:00PM - 7:00PM
Immunoreceptor Signaling II: New Methods for Probing Cell Si
gnaling

Room: Jefferson/Madison

Speaker 1 of 5
* Nir Hacohen, Massachusetts General Hospital, USA

Monday, January 11 | 5:00PM - 7:00PM
Immunoreceptor Signaling II: New Methods for Probing Cell Si
gnaling

Room: Jefferson/Madison

Speaker 2 of 5
Veit Hornung, Ludwig-Maximilians-University Munich, Germany
CRISPR/Cas Approaches to Analysis of Immune Cell Signaling

Monday, January 11 | 5:00PM - 7:00PM
Immunoreceptor Signaling II: New Methods for Probing Cell Si
gnaling

Room: Jefferson/Madison

Speaker 3 of 5
Bernard Malissen, Centre d'Immunologie de Marseille-Luminy, France
Engineered Systems for Analysis of Signaling Pathways in Primary Lymphocytes Using Quantitative Proteomics

Monday, January 11 | 5:00PM - 7:00PM
Immunoreceptor Signaling II: New Methods for Probing Cell Si
gnaling

Room: Jefferson/Madison

Speaker 4 of 5
Iain D.C. Fraser, NIAID, National Institutes of Health, USA
Interrogating Immune Signaling Systems with High-Throughput/High-Content Screening

Monday, January 11 | 5:00PM - 7:00PM
Immunoreceptor Signaling II: New Methods for Probing Cell Si
gnaling

Room: Jefferson/Madison

Speaker 5 of 5
Felix Meissner, Max Planck Institute of Biochemistry, Germany
Short Talk: Proteome Atlas of Circulating Human Immune Cells Reveals Intercellular Communication Structures

Monday, January 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Gallatin
No registration fees are used to fund alcohol served at this function.

Monday, January 11 | 7:30PM - 10:00PM
Poster Session 1
Room: Gallatin


Tuesday, January 12 | 7:00AM - 8:00AM
Breakfast
Room: Gallatin


Tuesday, January 12 | 8:00AM - 11:15AM
Modeling Signaling Pathways and Transcriptional Networks
Room: Jefferson/Madison

Speaker 1 of 7
* Dana Pe'er, Memorial Sloan Kettering Cancer Center, USA

Tuesday, January 12 | 8:00AM - 11:15AM
Modeling Signaling Pathways and Transcriptional Networks
Room: Jefferson/Madison

Speaker 2 of 7
Alan Aderem, Center for Infectious Disease Research, USA
Dissecting the Innate Immune System Using Tools of Systems Biology

Tuesday, January 12 | 8:00AM - 11:15AM
Modeling Signaling Pathways and Transcriptional Networks
Room: Jefferson/Madison

Speaker 3 of 7
Aviv Regev, Genentech, USA
Signaling Networks in Th17 CD4 T Cells

Tuesday, January 12 | 8:00AM - 11:15AM
Modeling Signaling Pathways and Transcriptional Networks
Room: Jefferson/Madison

Speaker 4 of 7
Harinder Singh, Cincinnati Children's Hospital Medical Center, USA
Gene Regulatory Networks Orchestrating Cell Fate Dynamics of Activated B Cells

Tuesday, January 12 | 8:00AM - 11:15AM
Modeling Signaling Pathways and Transcriptional Networks
Room: Jefferson/Madison

Speaker 5 of 7
Ellen V. Rothenberg, California Institute of Technology, USA
Transcriptional Networks in Developing Lymphocytes

Tuesday, January 12 | 8:00AM - 11:15AM
Modeling Signaling Pathways and Transcriptional Networks
Room: Jefferson/Madison

Speaker 6 of 7
Aaron J. Arvey, Gilead, USA
Short Talk: Genetic and Epigenetic Variation in the Lineage Specification of Regulatory T Cells

Tuesday, January 12 | 8:00AM - 11:15AM
Modeling Signaling Pathways and Transcriptional Networks
Room: Jefferson/Madison

Speaker 7 of 7
Vladimir Litvak, Sanofi US, USA
Short Talk: Decoding Transcriptional and Epigenetic Regulatory Networks in Macrophages

Tuesday, January 12 | 9:20AM - 9:40AM
Coffee Break
Room: Lower Atrium


Tuesday, January 12 | 11:15AM - 1:00PM
Poster Setup
Room: Gallatin


Tuesday, January 12 | 11:15AM - 2:30PM
On Own for Lunch


Tuesday, January 12 | 1:00PM - 10:00PM
Poster Viewing
Room: Gallatin


Tuesday, January 12 | 2:30PM - 4:30PM
Workshop 2: Human Systems Immunology
Room: Jefferson/Madison

Speaker 1 of 6
Lisa Marie Kronstad, Stanford University, USA
Human Natural Killer Cell Sensing of Influenza A Viruses

Tuesday, January 12 | 2:30PM - 4:30PM
Workshop 2: Human Systems Immunology
Room: Jefferson/Madison

Speaker 2 of 6
John P. Barton, University of California, Riverside, USA
Intra-Host HIV Evolution to Evade Cellular Immunity is Predictable

Tuesday, January 12 | 2:30PM - 4:30PM
Workshop 2: Human Systems Immunology
Room: Jefferson/Madison

Speaker 3 of 6
* Brittany A. Goods, Massachusetts Institute of Technology, USA
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis

Tuesday, January 12 | 2:30PM - 4:30PM
Workshop 2: Human Systems Immunology
Room: Jefferson/Madison

Speaker 4 of 6
Andrew Fiore-Gartland, Fred Hutchinson Cancer Research Institute, USA
Modular Cytokine Analysis Reveals Innate Correlates of Influenza Outcome in a Multicenter Study

Tuesday, January 12 | 2:30PM - 4:30PM
Workshop 2: Human Systems Immunology
Room: Jefferson/Madison

Speaker 5 of 6
Ning Jenny Jiang, University of Texas at Austin, USA
Accurate and High-Coverage Immune Repertoire Sequencing Reveals Characteristics of Antibody Repertoire Diversification in Young Children

Tuesday, January 12 | 2:30PM - 4:30PM
Workshop 2: Human Systems Immunology
Room: Jefferson/Madison

Speaker 6 of 6
Irit Gat-Viks, Tel-Aviv University, Israel
Modeling the Genetic and Immunological Basis of in vivo Phenotypes

Tuesday, January 12 | 4:30PM - 5:00PM
Coffee Available
Room: Lower Atrium


Tuesday, January 12 | 5:00PM - 7:00PM
Single Cell Analysis Modeling I
Room: Jefferson/Madison

Speaker 1 of 5
* Aviv Regev, Genentech, USA

Tuesday, January 12 | 5:00PM - 7:00PM
Single Cell Analysis Modeling I
Room: Jefferson/Madison

Speaker 2 of 5
Ronald N. Germain, NIAID, National Institutes of Health, USA
Imaging Immunity: Creating a Quantitative Spatiotemporal Understanding of Host Defense

Tuesday, January 12 | 5:00PM - 7:00PM
Single Cell Analysis Modeling I
Room: Jefferson/Madison

Speaker 3 of 5
Catherine A. Blish, Stanford University School of Medicine, USA
Defining Protective Immunologic Signatures

Tuesday, January 12 | 5:00PM - 7:00PM
Single Cell Analysis Modeling I
Room: Jefferson/Madison

Speaker 4 of 5
Michael Meyer-Hermann, Helmholtz Centre for Infection Research, Germany
Germinal Centres in vivo and in silico

Tuesday, January 12 | 5:00PM - 7:00PM
Single Cell Analysis Modeling I
Room: Jefferson/Madison

Speaker 5 of 5
Kelly Wen Li Chen, Massachusetts Institute of Technology, USA
Short Talk: Investigation of Cytokine-Mediated Intercellular Crosstalk in Normal and Inflammatory Conditions

Tuesday, January 12 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Gallatin
No registration fees are used to fund alcohol served at this function.

Tuesday, January 12 | 7:30PM - 10:00PM
Poster Session 2
Room: Gallatin


Wednesday, January 13 | 7:00AM - 8:00AM
Breakfast
Room: Gallatin


Wednesday, January 13 | 8:00AM - 11:00AM
Single Cell Analysis Modeling II
Room: Jefferson/Madison

Speaker 1 of 6
* Ronald N. Germain, NIAID, National Institutes of Health, USA

Wednesday, January 13 | 8:00AM - 11:00AM
Single Cell Analysis Modeling II
Room: Jefferson/Madison

Speaker 2 of 6
Dana Pe'er, Memorial Sloan Kettering Cancer Center, USA
Modeling Cellular Responses

Wednesday, January 13 | 8:00AM - 11:00AM
Single Cell Analysis Modeling II
Room: Jefferson/Madison

Speaker 3 of 6
Sarah Teichmann, Wellcome Sanger Institute, UK
Understanding Cellular Heterogeneity


Wednesday, January 13 | 8:00AM - 11:00AM
Single Cell Analysis Modeling II
Room: Jefferson/Madison

Speaker 4 of 6
Grégoire Altan-Bonnet, NCI, National Institutes of Health, USA
Modeling the Spatio-Temporal Heterogeneity of Cell-to-Cell Communications

Wednesday, January 13 | 8:00AM - 11:00AM
Single Cell Analysis Modeling II
Room: Jefferson/Madison

Speaker 5 of 6
Martin Meier-Schellersheim, NIAID, National Institutes of Health, USA
Computational Modelling Elucidates How MAPK Crosstalk Regulates Sensitivity of Macrophages Toward TLR4 Stimulation

Wednesday, January 13 | 8:00AM - 11:00AM
Single Cell Analysis Modeling II
Room: Jefferson/Madison

Speaker 6 of 6
Sayak Mukherjee, Ohio State University, USA
Short Talk: Reconstruction of Single Cell Signaling Trajectories using Snapshot Cytometry Data

Wednesday, January 13 | 9:20AM - 9:40AM
Coffee Break
Room: Lower Atrium


Wednesday, January 13 | 11:00AM - 1:00PM
Poster Setup
Room: Gallatin


Wednesday, January 13 | 11:00AM - 5:00PM
On Own for Lunch


Wednesday, January 13 | 1:00PM - 10:00PM
Poster Viewing
Room: Gallatin


Wednesday, January 13 | 4:30PM - 5:00PM
Coffee Available
Room: Lower Atrium


Wednesday, January 13 | 5:00PM - 7:00PM
Systems Analysis of Cancer and Model Organisms
Room: Jefferson/Madison

Speaker 1 of 5
* Suzanne Gaudet, Dana-Farber Cancer Institute/Harvard Medical School, USA

Wednesday, January 13 | 5:00PM - 7:00PM
Systems Analysis of Cancer and Model Organisms
Room: Jefferson/Madison

Speaker 2 of 5
Andrea Califano, Columbia University, USA
Systematic Elucidation of Druggable Dependencies in Human Malignancies: A New Take on Precision Medicine

Wednesday, January 13 | 5:00PM - 7:00PM
Systems Analysis of Cancer and Model Organisms
Room: Jefferson/Madison

Speaker 3 of 5
Kathryn Miller-Jensen, Yale University, USA
Discovering Macrophage Paracrine Signaling Networks from Single-Cell Data

Wednesday, January 13 | 5:00PM - 7:00PM
Systems Analysis of Cancer and Model Organisms
Room: Jefferson/Madison

Speaker 4 of 5
Catherine A.A. Beauchemin, Ryerson University, Canada
Modelling Viral Infection in vivo and in vitro

Wednesday, January 13 | 5:00PM - 7:00PM
Systems Analysis of Cancer and Model Organisms
Room: Jefferson/Madison

Speaker 5 of 5
Edward S. Lee, University of Glasgow, UK
Short Talk: Novel Computational Approaches to TCR Repertoire Analysis

Wednesday, January 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Gallatin
No registration fees are used to fund alcohol served at this function.

Wednesday, January 13 | 7:30PM - 10:00PM
Poster Session 3
Room: Gallatin


Thursday, January 14 | 7:00AM - 8:00AM
Breakfast
Room: Gallatin


Thursday, January 14 | 8:00AM - 11:00AM
Human Systems Immunology: Methods
Room: Jefferson/Madison

Speaker 1 of 7
* David Furman, Buck Institute for Research on Aging, USA

Thursday, January 14 | 8:00AM - 11:00AM
Human Systems Immunology: Methods
Room: Jefferson/Madison

Speaker 2 of 7
Damien Chaussabel, Sidra Medical and Research Center, Qatar
Systems Approaches to Health Maintenance and Immunological Knowledge Discovery

Thursday, January 14 | 8:00AM - 11:00AM
Human Systems Immunology: Methods
Room: Jefferson/Madison

Speaker 3 of 7
Alexandra-Chloé Villani, Broad Institute of MIT and Harvard, USA
Short Talk: Talk Title to be Announced

Thursday, January 14 | 8:00AM - 11:00AM
Human Systems Immunology: Methods
Room: Jefferson/Madison

Speaker 4 of 7
Linas Mazutis, Vilnius University, Lithuania
Short Talk: Barcoding and Sequencing Thousands of Individual Cells using Droplet Microfluidics

Thursday, January 14 | 8:00AM - 11:00AM
Human Systems Immunology: Methods
Room: Jefferson/Madison

Speaker 5 of 7
Matthew H. Spitzer, Stanford University, USA
Modeling Systems-Wide Immunity Reveals Coordinated Responses in Health and Cancer

Thursday, January 14 | 8:00AM - 11:00AM
Human Systems Immunology: Methods
Room: Jefferson/Madison

Speaker 6 of 7
John Tsang, NIAID, National Institutes of Health, USA
From Single Cells to Networks to Human Populations: Assessing and Utilizing Heterogeneity of the Immune System

Thursday, January 14 | 8:00AM - 11:00AM
Human Systems Immunology: Methods
Room: Jefferson/Madison

Speaker 7 of 7
Ayelet Alpert, Technion-Israel Institute of Technology, Israel
Short Talk: Baseline Matters: The Effect of Initial Immune State on Outcome of Septic Patients

Thursday, January 14 | 9:20AM - 9:40AM
Coffee Break
Room: Lower Atrium


Thursday, January 14 | 11:00AM - 2:30PM
On Own for Lunch


Thursday, January 14 | 2:30PM - 4:30PM
Workshop 3: Methodological Advances in Systems Immunology
Room: Jefferson/Madison

Speaker 1 of 6
* Matthew H. Spitzer, Stanford University, USA

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 3: Methodological Advances in Systems Immunology
Room: Jefferson/Madison

Speaker 2 of 6
Nathan Paul Manes, National Institutes of Health, USA
Targeted Proteomics-Driven Computational Modeling of the Chemotaxis and Toll-like Receptor Signaling Pathways in Macrophages

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 3: Methodological Advances in Systems Immunology
Room: Jefferson/Madison

Speaker 3 of 6
Andriy Morgun, Oregon State University, USA
Transkingdom Networks as a Model of Host-Microbiota Interactions

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 3: Methodological Advances in Systems Immunology
Room: Jefferson/Madison

Speaker 4 of 6
Denis Schapiro, University of Zurich, Switzerland
Imaging Mass Cytometry Reveals Neighboring Cell Interactions Amongst the Heterogeneity of Breast Cancer

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 3: Methodological Advances in Systems Immunology
Room: Jefferson/Madison

Speaker 5 of 6
Brian Kidd, Icahn School of Medicine at Mount Sinai, USA
Mapping the Effects of Drugs on the Immune System

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 3: Methodological Advances in Systems Immunology
Room: Jefferson/Madison

Speaker 6 of 6
Nienke Moret, Harvard University, USA
Controlling Regulatory T Cell Heterogeneity by Chemical Modification of Signaling Pathways

Thursday, January 14 | 4:30PM - 5:00PM
Coffee Available
Room: Lower Atrium


Thursday, January 14 | 5:00PM - 6:45PM
Human Systems Immunology: Biomedical Applications
Room: Jefferson/Madison

Speaker 1 of 3
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Long-term Consequences of Infection for Tissue Immunity and Metabolism

Thursday, January 14 | 5:00PM - 6:45PM
Human Systems Immunology: Biomedical Applications
Room: Jefferson/Madison

Speaker 2 of 3
* Anne O'Garra, Francis Crick Institute, UK
Systems Studies of Human Immune Responses to Infection

Thursday, January 14 | 5:00PM - 6:45PM
Human Systems Immunology: Biomedical Applications
Room: Jefferson/Madison

Speaker 3 of 3
Arup K. Chakraborty, Massachusetts Institute of Technology, USA
How to Hit HIV Where it Hurts by Integrating Sequencing, Statistical Inference, Mechanistic Models and Human Data

Thursday, January 14 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Jefferson/Madison


Thursday, January 14 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Gallatin
No registration fees are used to fund alcohol served at this function.

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