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Sunday, March 20 | 4:00PM - 8:00PM
Arrival and Registration
Room: Grand Foyer


Sunday, March 20 | 6:00PM - 8:00PM
Welcome Mixer
Room: Grand Foyer
No registration fees are used to fund alcohol served at this function.

Monday, March 21 | 7:00AM - 8:00AM
Breakfast
Room: Sea to Sky A


Monday, March 21 | 8:00AM - 11:00AM
Epigenetic Pathways
Room: Sea to Sky B/C

Speaker 1 of 6
* Luciano Di Croce, CRG - Center for Genomic Regulation, Spain

Monday, March 21 | 8:00AM - 11:00AM
Epigenetic Pathways
Room: Sea to Sky B/C

Speaker 2 of 6
Shelley L. Berger, University of Pennsylvania, USA
Histone Acetylation Pathways in Learning and Memory

Monday, March 21 | 8:00AM - 11:00AM
Epigenetic Pathways
Room: Sea to Sky B/C

Speaker 3 of 6
Yang Shi, Children's Hospital Boston, Harvard Medical School, USA
Histone Methylation Regulation, Recognition and Link to Human Disease

Monday, March 21 | 8:00AM - 11:00AM
Epigenetic Pathways
Room: Sea to Sky B/C

Speaker 4 of 6
Tony Kouzarides, University of Cambridge, UK
Role of ncRNAs in Transcription and Cancer

Monday, March 21 | 8:00AM - 11:00AM
Epigenetic Pathways
Room: Sea to Sky B/C

Speaker 5 of 6
Salvador Aznar Benitah, ICREA and Institute for Research in Biomedicine, Spain
Epigenetic Regulation of Adult Stem Cell Function in Homeostasis, Aging and Cancer

Monday, March 21 | 8:00AM - 11:00AM
Epigenetic Pathways
Room: Sea to Sky B/C

Speaker 6 of 6
Ian Chambers, University of Edinburgh, UK
Short Talk: Extinction of Esrrb Triggers the Dismantling of Naïve Pluripotency and Marks Commitment to Differentiation

Monday, March 21 | 9:20AM - 9:40AM
Coffee Break
Room: Grand Foyer


Monday, March 21 | 11:00AM - 1:00PM
Poster Setup
Room: Sea to Sky A


Monday, March 21 | 11:00AM - 2:30PM
On Own for Lunch


Monday, March 21 | 1:00PM - 10:00PM
Poster Viewing
Room: Sea to Sky A


Monday, March 21 | 2:30PM - 3:30PM
Workshop 1: ENCODE Data Analysis and Visualization
Room: Sea to Sky B/C

Speaker 1 of 1
* Feng Yue, Pennsylvania State University, USA

Monday, March 21 | 3:30PM - 4:30PM
Workshop 2: Epigenomic Annotation of Genetic Variants using
the Washington University Epigenome Browser
Room: Sea to Sky B/C

Speaker 1 of 1
* Ting Wang, Washington University, USA

Monday, March 21 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer


Monday, March 21 | 5:00PM - 7:00PM
DNA Methylation in Stem Cells
Room: Sea to Sky B/C

Speaker 1 of 5
* Wolf Reik, Babraham Institute, UK

Monday, March 21 | 5:00PM - 7:00PM
DNA Methylation in Stem Cells
Room: Sea to Sky B/C

Speaker 2 of 5
Bing Ren, Ludwig Institute for Cancer Research, USA
Global Analysis of Transcriptional Enhancers in Embryonic Stem Cells

Monday, March 21 | 5:00PM - 7:00PM
DNA Methylation in Stem Cells
Room: Sea to Sky B/C

Speaker 3 of 5
Anjana Rao, La Jolla Institute for Allergy and Immunology, USA
TET Proteins and 5-Methylcytosine Oxidation

Monday, March 21 | 5:00PM - 7:00PM
DNA Methylation in Stem Cells
Room: Sea to Sky B/C

Speaker 4 of 5
Or P. Gozani, Stanford University, USA
New Roles for Lysine Methylation Signaling in Epigenetic and Disease Regulation

Monday, March 21 | 5:00PM - 7:00PM
DNA Methylation in Stem Cells
Room: Sea to Sky B/C

Speaker 5 of 5
Sandra Peiró, Fundació IMIM, Spain
Short Talk: H3K4ox-mediated Chromatin Condensation Protects Breast Cancer Cells from the DNA Damage Repair Machinery

Monday, March 21 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sea to Sky A
No registration fees are used to fund alcohol served at this function.

Monday, March 21 | 7:30PM - 10:00PM
Poster Session 1
Room: Sea to Sky A


Tuesday, March 22 | 7:00AM - 8:00AM
Breakfast
Room: Sea to Sky A


Tuesday, March 22 | 7:30AM - 8:00AM
Poster Setup
Room: Sea to Sky A


Tuesday, March 22 | 8:00AM - 5:00PM
Poster Viewing
Room: Sea to Sky A


Tuesday, March 22 | 8:00AM - 11:15AM
Epigenetic Chromatin Complexes
Room: Sea to Sky B/C

Speaker 1 of 7
* Giacomo Cavalli, Institute of Human Genetics, France

Tuesday, March 22 | 8:00AM - 11:15AM
Epigenetic Chromatin Complexes
Room: Sea to Sky B/C

Speaker 2 of 7
Anne Brunet, Stanford University, USA
Epigenetic Regulation of Aging

Tuesday, March 22 | 8:00AM - 11:15AM
Epigenetic Chromatin Complexes
Room: Sea to Sky B/C

Speaker 3 of 7
Danny F. Reinberg, HHMI/New York University, USA
Chromatin Regulation by Polycomb Complexes

Tuesday, March 22 | 8:00AM - 11:15AM
Epigenetic Chromatin Complexes
Room: Sea to Sky B/C

Speaker 4 of 7
Luciano Di Croce, CRG - Center for Genomic Regulation, Spain
Polycomb Orchestrates Gene Regulation Dynamics in Cell Differentiation and Cancer

Tuesday, March 22 | 8:00AM - 11:15AM
Epigenetic Chromatin Complexes
Room: Sea to Sky B/C

Speaker 5 of 7
Yujiang Geno Shi, Harvard Medical School, USA
Glucose Signaling to Reprogramming Chromatin via a Molecular Switch on TET2

Tuesday, March 22 | 8:00AM - 11:15AM
Epigenetic Chromatin Complexes
Room: Sea to Sky B/C

Speaker 6 of 7
Adrian P. Bracken, Trinity College Dublin, Ireland
Short Talk: Polycomb Repressive Complex 2 (PRC2) in Proliferation Control and Cancer

Tuesday, March 22 | 8:00AM - 11:15AM
Epigenetic Chromatin Complexes
Room: Sea to Sky B/C

Speaker 7 of 7
Mafalda Almeida, University of Oxford, UK
Short Talk: Mechanisms of Xist-dependent Polycomb Recruitment

Tuesday, March 22 | 9:20AM - 9:40AM
Coffee Break
Room: Grand Foyer


Tuesday, March 22 | 11:15AM - 12:00PM
Lunch
Room: Sea to Sky A


Tuesday, March 22 | 12:00PM - 2:30PM
Poster Session 2
Room: Sea to Sky A


Tuesday, March 22 | 2:30PM - 4:30PM
Workshop 3: Connecting ncRNA, Stem Cells and Higher-Ordered
Chromatin Structure
Room: Sea to Sky B/C

Speaker 1 of 5
Rebecca Berrens, Babraham Institute, UK
Acute Demethylation of Transposons in ES Cells Reveals Regulation by Small RNA Pathways

Tuesday, March 22 | 2:30PM - 4:30PM
Workshop 3: Connecting ncRNA, Stem Cells and Higher-Ordered
Chromatin Structure
Room: Sea to Sky B/C

Speaker 2 of 5
* M. Ryan Corces, Stanford University, USA
Lineage-specific and Single Cell Chromatin Accessibility Charts Human Hematopoiesis and Leukemia Evolution

Tuesday, March 22 | 2:30PM - 4:30PM
Workshop 3: Connecting ncRNA, Stem Cells and Higher-Ordered
Chromatin Structure
Room: Sea to Sky B/C

Speaker 3 of 5
Alessandro Bonetti, Karolinska Institutet, Sweden
Identification and Characterization of Non-coding RNAs Associated with Chromatin in Pluripotency

Tuesday, March 22 | 2:30PM - 4:30PM
Workshop 3: Connecting ncRNA, Stem Cells and Higher-Ordered
Chromatin Structure
Room: Sea to Sky B/C

Speaker 4 of 5
Paula Freire-Pritchett, Babraham Institute, UK
Global Rewiring of Enhancer-promoter Interactions during Early Lineage Commitment in Human Embryonic Stem Cells

Tuesday, March 22 | 2:30PM - 4:30PM
Workshop 3: Connecting ncRNA, Stem Cells and Higher-Ordered
Chromatin Structure
Room: Sea to Sky B/C

Speaker 5 of 5
Kunle Demuren, Massachusetts Institute of Technology, USA
Determining Molecular Mediators of Enhancer Activation during Cardiomyocyte Differentiation

Tuesday, March 22 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer


Tuesday, March 22 | 5:00PM - 7:00PM
Chromatin Organization
Room: Sea to Sky B/C

Speaker 1 of 6
* Shelley L. Berger, University of Pennsylvania, USA

Tuesday, March 22 | 5:00PM - 7:00PM
Chromatin Organization
Room: Sea to Sky B/C

Speaker 2 of 6
François Fuks, Université Libre de Bruxelles, Belgium
Mechanisms of TETs & Hydroxymethylation

Tuesday, March 22 | 5:00PM - 7:00PM
Chromatin Organization
Room: Sea to Sky B/C

Speaker 3 of 6
Francois Aymard, University of Toulouse, France
Short Talk: Chromosome and Chromatin Dynamics during Double Strand Break Repair

Tuesday, March 22 | 5:00PM - 7:00PM
Chromatin Organization
Room: Sea to Sky B/C

Speaker 4 of 6
Abraham S. Weintraub, Cedilla Therapeutics, USA
Short Talk: Activation of Proto-Oncogenes by Disruption of Chromosome Neighborhoods

Tuesday, March 22 | 5:00PM - 7:00PM
Chromatin Organization
Room: Sea to Sky B/C

Speaker 5 of 6
Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Replication-Coupled Silencing and Spreading with RNAi

Tuesday, March 22 | 5:00PM - 7:00PM
Chromatin Organization
Room: Sea to Sky B/C

Speaker 6 of 6
Tian Tian, Center for Genomic Regulation, Spain
Short Talk: Whsc1 is Required for the Exit from Pluripotency and Efficient Meso-endoderm Differentiation

Tuesday, March 22 | 7:00PM - 7:00PM
On Own for Dinner


Wednesday, March 23 | 7:00AM - 8:00AM
Breakfast
Room: Sea to Sky A


Wednesday, March 23 | 8:00AM - 11:15AM
Chromatin in Stem Cells
Room: Sea to Sky B/C

Speaker 1 of 7
* Salvador Aznar Benitah, ICREA and Institute for Research in Biomedicine, Spain

Wednesday, March 23 | 8:00AM - 11:15AM
Chromatin in Stem Cells
Room: Sea to Sky B/C

Speaker 2 of 7
Kristian Helin, University of Copenhagen and Memorial Sloan Kettering Cancer Center, Denmark
Histone Methylation in Transcriptional Regulation, Differentiation and Cancer

Wednesday, March 23 | 8:00AM - 11:15AM
Chromatin in Stem Cells
Room: Sea to Sky B/C

Speaker 3 of 7
Giacomo Cavalli, Institute of Human Genetics, France
Genome Regulation by Polycomb Proteins, between Epigenetic Inheritance and Dynamic Gene Regulation

Wednesday, March 23 | 8:00AM - 11:15AM
Chromatin in Stem Cells
Room: Sea to Sky B/C

Speaker 4 of 7
Wolf Reik, Babraham Institute, UK
Epigenetic Reprogramming in Mammalian Development

Wednesday, March 23 | 8:00AM - 11:15AM
Chromatin in Stem Cells
Room: Sea to Sky B/C

Speaker 5 of 7
Rab K. Prinjha, GlaxoSmithKline, UK
Epigenetic Targets for the Treatment of Human Diseases

Wednesday, March 23 | 8:00AM - 11:15AM
Chromatin in Stem Cells
Room: Sea to Sky B/C

Speaker 6 of 7
Alexander J. Ruthenburg, University of Chicago, USA
Short Talk: Biochemical Fractionation Reveals Highly Selective Binding Partners for 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in DNA

Wednesday, March 23 | 8:00AM - 11:15AM
Chromatin in Stem Cells
Room: Sea to Sky B/C

Speaker 7 of 7
Chao Lu, Columbia University, USA
Short Talk: Oncohistone Mutations Reprogram Chromatin Landscape to Impair Cell Differentiation

Wednesday, March 23 | 9:20AM - 9:40AM
Coffee Break
Room: Grand Foyer


Wednesday, March 23 | 11:15AM - 1:00PM
Poster Setup
Room: Sea to Sky A


Wednesday, March 23 | 11:15AM - 2:30PM
On Own for Lunch


Wednesday, March 23 | 1:00PM - 10:00PM
Poster Viewing
Room: Sea to Sky A


Wednesday, March 23 | 2:30PM - 4:30PM
Workshop 4: How RNA Modifications Impact Chromatin Structure
and Stem Cell Fate
Room: Sea to Sky B/C

Speaker 1 of 6
E. Megan Flynn, Genentech, Inc., USA
Specificity of Human Bromodomains for Histone H3, H4 Peptides

Wednesday, March 23 | 2:30PM - 4:30PM
Workshop 4: How RNA Modifications Impact Chromatin Structure
and Stem Cell Fate
Room: Sea to Sky B/C

Speaker 2 of 6
Felice Frey, Max-Planck Institute of Biohemistry, Germany
Molecular Basis for Targeting PRC1 to Polycomb Response Elements

Wednesday, March 23 | 2:30PM - 4:30PM
Workshop 4: How RNA Modifications Impact Chromatin Structure
and Stem Cell Fate
Room: Sea to Sky B/C

Speaker 3 of 6
Yoshihiro Matsumura, University of Tokyo, Japan
H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipogenesis

Wednesday, March 23 | 2:30PM - 4:30PM
Workshop 4: How RNA Modifications Impact Chromatin Structure
and Stem Cell Fate
Room: Sea to Sky B/C

Speaker 4 of 6
Yuanyuan Li, Tsinghua University, School of Medicine, China
Journal of Biological Chemistry, Herb Tabor Young Investigator: Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain

Wednesday, March 23 | 2:30PM - 4:30PM
Workshop 4: How RNA Modifications Impact Chromatin Structure
and Stem Cell Fate
Room: Sea to Sky B/C

Speaker 5 of 6
Sharmistha Kundu, Massachusetts General Hospital, USA
3D-Architecture Remodeling of Chromatin by PRC1

Wednesday, March 23 | 2:30PM - 4:30PM
Workshop 4: How RNA Modifications Impact Chromatin Structure
and Stem Cell Fate
Room: Sea to Sky B/C

Speaker 6 of 6
* Marc-Werner Dobenecker, Rockefeller University, USA
The Role of PRC2 in Systemic Inflammation and Autoimmunity

Wednesday, March 23 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer


Wednesday, March 23 | 5:00PM - 7:00PM
Chromatin and Cancer
Room: Sea to Sky B/C

Speaker 1 of 5
* Or P. Gozani, Stanford University, USA

Wednesday, March 23 | 5:00PM - 7:00PM
Chromatin and Cancer
Room: Sea to Sky B/C

Speaker 2 of 5
Johnathan R. Whetstine, Fox Chase Cancer Center, USA
Epigenetic Mechanisms Driving Copy Number Alterations and Drug Resistant Gene Selection

Wednesday, March 23 | 5:00PM - 7:00PM
Chromatin and Cancer
Room: Sea to Sky B/C

Speaker 3 of 5
Robert J. Sims, Constellation Pharmaceuticals, USA
Bromodomain Inhibition as a Strategy to Target Oncogenic Signaling Pathways

Wednesday, March 23 | 5:00PM - 7:00PM
Chromatin and Cancer
Room: Sea to Sky B/C

Speaker 4 of 5
Bradley E. Bernstein, Massachusetts General Hospital, USA
Epigenetic Mechanisms of Brain Tumor Initiation and Evolution

Wednesday, March 23 | 5:00PM - 7:00PM
Chromatin and Cancer
Room: Sea to Sky B/C

Speaker 5 of 5
Prathamesh Thangaraj Nadar Ponniah, Technion Israel Institute of Technology, Israel
Short Talk: RNA-dependent Chromatin Localization of KDM4D Lysine Demethylase Promotes H3K9me3 Demethylation

Wednesday, March 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sea to Sky A
No registration fees are used to fund alcohol served at this function.

Wednesday, March 23 | 7:30PM - 10:00PM
Poster Session 3
Room: Sea to Sky A


Thursday, March 24 | 7:00AM - 8:00AM
Breakfast
Room: Sea to Sky A


Thursday, March 24 | 8:00AM - 11:15AM
ncRNA and Enhancers
Room: Sea to Sky B/C

Speaker 1 of 8
* Tony Kouzarides, University of Cambridge, UK

Thursday, March 24 | 8:00AM - 11:15AM
ncRNA and Enhancers
Room: Sea to Sky B/C

Speaker 2 of 8
Victor G. Corces, Emory University School of Medicine, USA
The Role of Architectural Proteins in the 3D Organization of the Genome

Thursday, March 24 | 8:00AM - 11:15AM
ncRNA and Enhancers
Room: Sea to Sky B/C

Speaker 3 of 8
Saverio Minucci, IEO Milan, Italy
Chromatin Alterations in Leukemogenesis

Thursday, March 24 | 8:00AM - 11:15AM
ncRNA and Enhancers
Room: Sea to Sky B/C

Speaker 4 of 8
James J. Morrow, Case Western Reserve University School of Medicine, USA
Short Talk: Positively Selected Enhancer Elements Endow Tumor Cells with Metastatic Competence

Thursday, March 24 | 8:00AM - 11:15AM
ncRNA and Enhancers
Room: Sea to Sky B/C

Speaker 5 of 8
Jacques Drouin, Institut de Recherches Cliniques de Montréal, Canada
Short Talk: Talk Title to be Announced

Thursday, March 24 | 8:00AM - 11:15AM
ncRNA and Enhancers
Room: Sea to Sky B/C

Speaker 6 of 8
Eileen E.M. Furlong, European Molecular Biology Laboratory, Germany
Chromatin Topology during Embryonic Development

Thursday, March 24 | 8:00AM - 11:15AM
ncRNA and Enhancers
Room: Sea to Sky B/C

Speaker 7 of 8
Keiko Ozato, NICHD, National Institutes of Health, USA
Short Talk: Epigenetic Chromatin Marks in Innate Immune Responses: Functional Consequences

Thursday, March 24 | 8:00AM - 11:15AM
ncRNA and Enhancers
Room: Sea to Sky B/C

Speaker 8 of 8
Kiyomi Raye Kaneshiro, University of California, Santa Cruz, USA
Short Talk: Transmission of Gamete-Inherited Chromatin States

Thursday, March 24 | 9:20AM - 9:40AM
Coffee Break
Room: Grand Foyer


Thursday, March 24 | 11:15AM - 5:00PM
On Own for Lunch


Thursday, March 24 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer


Thursday, March 24 | 5:00PM - 7:00PM
Regulation of Transcription in Stem Cells
Room: Sea to Sky B/C

Speaker 1 of 6
* Yang Shi, Children's Hospital Boston, Harvard Medical School, USA

Thursday, March 24 | 5:00PM - 7:00PM
Regulation of Transcription in Stem Cells
Room: Sea to Sky B/C

Speaker 2 of 6
Jeannie T. Lee, Massachusetts General Hospital / Harvard Medical School, USA
The Roles of Long Noncoding RNA in Epigenetic Regulation

Thursday, March 24 | 5:00PM - 7:00PM
Regulation of Transcription in Stem Cells
Room: Sea to Sky B/C

Speaker 3 of 6
Masami Horikoshi, University of Tokyo, Japan
Short Talk: Uncovering Ancient Transcription Systems with a Novel Evolutionary Indicator

Thursday, March 24 | 5:00PM - 7:00PM
Regulation of Transcription in Stem Cells
Room: Sea to Sky B/C

Speaker 4 of 6
Melanie A. Eckersley-Maslin, Babraham Institute, UK
Short Talk: MERVL Endogenous Retrovirus Activation Induces Genome-Wide DNA Demethylation

Thursday, March 24 | 5:00PM - 7:00PM
Regulation of Transcription in Stem Cells
Room: Sea to Sky B/C

Speaker 5 of 6
Raja Jothi, NIEHS, National Institutes of Health, USA
Short Talk: Transcription at Intragenic Enhancers Attenuate Gene Expression

Thursday, March 24 | 5:00PM - 7:00PM
Regulation of Transcription in Stem Cells
Room: Sea to Sky B/C

Speaker 6 of 6
Chuan He, University of Chicago, USA
Reversible RNA Methylation in Gene Expression Regulation

Thursday, March 24 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Sea to Sky B/C


Thursday, March 24 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Sea to Sky A
No registration fees are used to fund alcohol served at this function.

Thursday, March 24 | 8:00PM - 11:00PM
Entertainment
Room: Sea to Sky A
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, March 24 | 8:00PM - 11:00PM
Cash Bar
Room: Sea to Sky A


Friday, March 25 | 10:25AM - 10:25AM
Departure


*Session Chair.

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