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Web Desc
Heart Failure: Genetics, Genomics and Epigenetics
joint with Cardiac Development, Regeneration and Repair
Organizer(s): Stuart A. Cook, Christine E. Seidman and Yigal M. Pinto
Date: April 03 - 07, 2016
Location: Snowbird Resort, Snowbird, UT, USA
Sponsored by Bayer HealthCare Pharmaceuticals, Pfizer Inc. and Takeda Pharmaceutical Company Limited
Summary of Meeting:
Heart failure (HF) is a worldwide epidemic with treatments costing tens of billions of dollars every year. Despite this investment, HF therapies have limited efficacy in reducing disease progression. Recent insights in fundamental myocyte biology, HF etiologies and pathogenic mechanisms are propelling new strategies to treat and prevent HF. This meeting will explore biologic and technical advances that inform the genetic architecture, molecular pathogenesis and innovative approaches to treat HF. This comes at a time when very large human HF datasets are available and can be interrogated using advanced computational and bioinformatic approaches. Specific aims are to: 1) Consider genes, molecules, signaling pathways and biomarkers involved in systolic and diastolic HF in humans; 2) Explore disease mechanisms underlying HF in model systems; 3) Understand the role of epigenetics, miRNAs and lncRNAs in HF pathogenesis; and 4) Review translational programs in genomic, pharmacologic and cell-based therapeutics to treat HF. The outcomes of this meeting should be far-reaching for basic, translational and clinical communities. The meeting should also provide an excellent training program for junior scientists and serve as a catalyst for collaboration among research, clinical and industrial participants. This meeting is being held in conjunction with the “Cardiac Development, Regeneration and Repair” meeting that provides an outstanding opportunity for joint sessions in genetics, iPSC disease modeling, stem cell therapeutics and epigenetics.
Scholarship Deadline: December 3 2015
Discounted Abstract Deadline: December 3 2015
Abstract Deadline: January 7 2016
Discounted Registration Deadline: February 4 2016
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bayer HealthCare PharmaceuticalsPfizer Inc.Takeda Pharmaceutical Company Limited
We gratefully acknowledge additional support for this conference from:

American Heart Association's Council on Functional Genomics and Translational Biology
Bethyl Laboratories, Inc.Cytokinetics, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Heart, Lung, and Blood Institute (NHLBI)
Grant No. 1R13HL131204-01
Funding for this conference was made possible (in part) by 1R13HL131204-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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