Common Mechanisms of Neurodegeneration joint with Microglia in the Brain Organizer(s): Bradley T. Hyman, Adriano M. Aguzzi and Ricardo E. Dolmetsch Date: June 12 - 16, 2016 Location: Keystone Resort, Keystone, CO, USARecent advances in understanding the genetics and underlying mechanisms of neurodegenerative diseases including prion diseases, Alzheimer’s, Parkinson’s, ALS and frontotemporal dementia have revealed overlaps of phenotypes, genetic risks and biological mechanisms across this spectrum of disorders. The “common mechanisms” include protein templating, glial and inflammatory mechanisms, new understanding of RNA-based toxicity and of toxicity associated with protein misfolding, and common downstream mechanisms affecting synaptic function. Moreover, because there appear to be common mechanisms at play, recent progress in therapeutic approaches targeting one of these disorders may have applicability across the whole range of disorders. This Keystone Symposia conference will enable the in-depth exploration of these various aspects of commonality across neurodegenerative disorders. Scholarship Deadline: February 11 2016 Discounted Abstract Deadline: February 11 2016 Abstract Deadline: March 10 2016 Discounted Registration Deadline: April 12 2016 We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Eli Lilly and Company
Novartis Institutes for BioMedical Research
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:  We gratefully acknowledge the generous grant for this conference provided by: National Institute of Neurological Disorders and Stroke (NINDS)Grant No. 1R13NS096941-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. |