Mononuclear Phagocytes in Health, Immune Defense and Disease
Organizer(s): Steffen Jung and Miriam MeradDate: April 30 - May 04, 2017
Location: Hyatt Regency Austin, Austin, TX, USA
Mononuclear phagocytes (MNP) are immune cells that are uniquely equipped to sense and respond to environmental cues by promoting tissue homeostasis or initiating tissue repair and immunity. MNP also contribute significantly to tissue pathologies, and their manipulation holds considerable therapeutic potential. MNP display major functional specializations. Most macrophages are established before birth and perform tissue-specific functions in organ development and homeostasis. Short-lived classical dendritic cells (DC) are specialized in triggering adaptive T cell immunity. Monocytes complement macrophages and DC as highly plastic cells, in particular during inflammation. While MNP subsets have been identified, individual contributions to health and disease are not well-defined. Breathtaking technological advance in genomic profiling of populations and single cells is revealing the breadth of MNP functions and identifying molecular checkpoints for targeted therapeutic intervention. These molecular efforts are paralleled by astounding progress in imaging capabilities, enabling the study of the cells in their physiological context. This meeting therefore aims to: 1) Cover recent progress in the field, revealing novel and differential contributions of MNP in physiological processes, and identify critical knowledge gaps; 2) Stimulate scientific exchange, in particular between clinicians and researchers, to better translate findings from animal models into human settings and brainstorm regarding novel therapeutic intervention; and 3) Develop novel conceptual frameworks for future studies of MNP in health and disease.
Scholarship Deadline: January 9 2017
Discounted Abstract Deadline: January 9 2017
Abstract Deadline: January 31 2017
Discounted Registration Deadline: February 28 2017
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
EMBO Young Investigator Programme
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
We gratefully acknowledge the generous grant for this conference provided by:National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI131438-01
Funding for this conference was made possible (in part) by AI 131438-01 from the National Institute of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.