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Tuesday, January 16 | 4:00PM - 8:00PM
Arrival and Registration
Room: Foyer


Tuesday, January 16 | 6:00PM - 8:00PM
Welcome Mixer
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Wednesday, January 17 | 7:00AM - 8:00AM
Breakfast
Room: Breckenridge Ballroom


Wednesday, January 17 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Colorado Ballroom

Speaker 1 of 3
* Daniel C. Douek, NIAID, National Institutes of Health, USA

Wednesday, January 17 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Colorado Ballroom

Speaker 2 of 3
* W. Nicholas Haining, Merck Research Laboratories, USA

Wednesday, January 17 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Colorado Ballroom

Speaker 3 of 3
Rafi Ahmed, Emory University School of Medicine, USA
A New Look at T Cell Exhaustion

Wednesday, January 17 | 9:00AM - 11:30AM
Adoptive T Cell Therapy for Cancer
Room: Colorado Ballroom

Speaker 1 of 7
* Susan M. Kaech, The Salk Institute, USA

Wednesday, January 17 | 9:00AM - 11:30AM
Adoptive T Cell Therapy for Cancer
Room: Colorado Ballroom

Speaker 2 of 7
Crystal L. Mackall, Stanford University, USA
Use of Adoptive T Cell Transfer in Pediatric Patients

Wednesday, January 17 | 9:00AM - 11:30AM
Adoptive T Cell Therapy for Cancer
Room: Colorado Ballroom


Coffee Break

Wednesday, January 17 | 9:00AM - 11:30AM
Adoptive T Cell Therapy for Cancer
Room: Colorado Ballroom

Speaker 4 of 7
Cassian Yee, University of Texas MD Anderson Cancer Center, USA
Endogenous T Cell Therapy: Finding Dory


Wednesday, January 17 | 9:00AM - 11:30AM
Adoptive T Cell Therapy for Cancer
Room: Colorado Ballroom

Speaker 5 of 7
Michael C. Jensen, Seattle Children's Research Institute, USA
Overcoming Barriers to Achieving Curative Outcomes Following CD19CAR T Cell Therapy For Recurrent/Refractory Pediatric ALL

Wednesday, January 17 | 9:00AM - 11:30AM
Adoptive T Cell Therapy for Cancer
Room: Colorado Ballroom

Speaker 6 of 7
Cyrille J. Cohen, Bar-Ilan University, Israel
Short Talk: Improved Targeting of Multiple Tumors and Viral-Infected Cells using T-Cells Engineered to Express NCR-Based Chimeric Receptors

Wednesday, January 17 | 9:00AM - 11:30AM
Adoptive T Cell Therapy for Cancer
Room: Colorado Ballroom

Speaker 7 of 7
Lexus Johnson, University of Pennsylvania, USA
Short Talk: Intratumoral Immune Activation Informs Rational CAR T Cell Design

Wednesday, January 17 | 11:30AM - 5:00PM
On Own for Lunch


Wednesday, January 17 | 11:30AM - 1:00PM
Poster Setup
Room: Breckenridge Ballroom


Wednesday, January 17 | 1:00PM - 10:00PM
Poster Viewing
Room: Breckenridge Ballroom


Wednesday, January 17 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, January 17 | 5:00PM - 7:00PM
T Cells and their Microenvironment
Room: Colorado Ballroom

Speaker 1 of 5
* W. Nicholas Haining, Merck Research Laboratories, USA

Wednesday, January 17 | 5:00PM - 7:00PM
T Cells and their Microenvironment
Room: Colorado Ballroom

Speaker 2 of 5
Daniel C. Douek, NIAID, National Institutes of Health, USA
Influence of the Systemic Microbiome on Inflammation During HIV Infection

Wednesday, January 17 | 5:00PM - 7:00PM
T Cells and their Microenvironment
Room: Colorado Ballroom

Speaker 3 of 5
David G. Brooks, Princess Margaret Cancer Center, Canada
Type I Interferons and Inflammation in T Cell Immunity

Wednesday, January 17 | 5:00PM - 7:00PM
T Cells and their Microenvironment
Room: Colorado Ballroom

Speaker 4 of 5
Susan M. Kaech, The Salk Institute, USA
Anti-Tumor T Cells: You Are What You Eat

Wednesday, January 17 | 5:00PM - 7:00PM
T Cells and their Microenvironment
Room: Colorado Ballroom

Speaker 5 of 5
Rafick Sekaly, Emory University, USA
Short Talk: PD-1 and IL-1 Control Two Independent Mechanisms of Immune Dysfunction and Response to Treatment in Cancer and HIV

Wednesday, January 17 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Breckenridge Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, January 17 | 7:30PM - 10:00PM
Poster Session 1
Room: Breckenridge Ballroom


Thursday, January 18 | 7:00AM - 8:00AM
Breakfast
Room: Breckenridge Ballroom


Thursday, January 18 | 8:00AM - 11:15AM
Basic Biology of T Cell Exhaustion
Room: Colorado Ballroom

Speaker 1 of 8
* E. John Wherry, University of Pennsylvania, USA

Thursday, January 18 | 8:00AM - 11:15AM
Basic Biology of T Cell Exhaustion
Room: Colorado Ballroom

Speaker 2 of 8
W. Nicholas Haining, Merck Research Laboratories, USA
The Epigenetic Landscape of T Cell Exhaustion

Thursday, January 18 | 8:00AM - 11:15AM
Basic Biology of T Cell Exhaustion
Room: Colorado Ballroom

Speaker 3 of 8
Ananda W. Goldrath, University of California, San Diego, USA
Transcriptional Regulation of CD8 T Cell Immunity

Thursday, January 18 | 8:00AM - 11:15AM
Basic Biology of T Cell Exhaustion
Room: Colorado Ballroom


Coffee Break

Thursday, January 18 | 8:00AM - 11:15AM
Basic Biology of T Cell Exhaustion
Room: Colorado Ballroom

Speaker 5 of 8
Andrea Schietinger, Memorial Sloan Kettering Cancer Center, USA
Tumor-Specific T Cell Dysfunction

Thursday, January 18 | 8:00AM - 11:15AM
Basic Biology of T Cell Exhaustion
Room: Colorado Ballroom

Speaker 6 of 8
Dietmar Zehn, Technical University of Munich, Germany
Subsets and T Cell Differentiation in Chronic LCMV Infection

Thursday, January 18 | 8:00AM - 11:15AM
Basic Biology of T Cell Exhaustion
Room: Colorado Ballroom

Speaker 7 of 8
Curtis H. Cai, University of New South Wales, Australia
Short Talk: Elucidating the Factors Associated with Dysfunctional T-cell Responses in HCV Infection using scRNA-seq and Functional Analyses

Thursday, January 18 | 8:00AM - 11:15AM
Basic Biology of T Cell Exhaustion
Room: Colorado Ballroom

Speaker 8 of 8
Jennifer M. Dan, University of California, San Diego, USA
Short Talk: Recurrent Group A Streptococcus Tonsillitis Is a Genetic Immunosusceptibility Disease with Aberrant Follicular
Helper CD4+ T Cells


Thursday, January 18 | 11:15AM - 5:00PM
On Own for Lunch


Thursday, January 18 | 11:15AM - 1:00PM
Poster Setup
Room: Breckenridge Ballroom


Thursday, January 18 | 1:00PM - 10:00PM
Poster Viewing
Room: Breckenridge Ballroom


Thursday, January 18 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, January 18 | 5:00PM - 7:00PM
Adoptive T Cell Transfer for Infection
Room: Colorado Ballroom

Speaker 1 of 5
* Robert Thimme, University Medical Center Freiburg, Germany

Thursday, January 18 | 5:00PM - 7:00PM
Adoptive T Cell Transfer for Infection
Room: Colorado Ballroom

Speaker 2 of 5
Philip D. Greenberg, University of Washington, USA
Novel Approaches to Isolating Receptors and Engineering Cells to Target Tumor Antigens

Thursday, January 18 | 5:00PM - 7:00PM
Adoptive T Cell Transfer for Infection
Room: Colorado Ballroom

Speaker 3 of 5
James L. Riley, University of Pennsylvania, USA
Engineering T Cells to Functionally Cure HIV-1 Infection

Thursday, January 18 | 5:00PM - 7:00PM
Adoptive T Cell Transfer for Infection
Room: Colorado Ballroom

Speaker 4 of 5
Catherine M. Bollard, Children’s National Health System, USA
Virus-Specific T Cells Post HSCT- Broadening Applicability

Thursday, January 18 | 5:00PM - 7:00PM
Adoptive T Cell Transfer for Infection
Room: Colorado Ballroom

Speaker 5 of 5
Sanjivan Sanjivan Gautam, NCI, National Institutes of Health, USA
Short Talk: The Transcription Factor Myb Enhances CD8+ T Cell Memory and Anti-Tumor Function by Inducing Tcf7 and Restraining Zeb2 Transcription

Thursday, January 18 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Breckenridge Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, January 18 | 7:30PM - 10:00PM
Poster Session 2
Room: Breckenridge Ballroom


Friday, January 19 | 7:00AM - 8:00AM
Breakfast
Room: Breckenridge Ballroom


Friday, January 19 | 8:00AM - 11:15AM
Basic Biology of Inhibitory Receptors
Room: Colorado Ballroom

Speaker 1 of 8
* Rafick Sekaly, Emory University, USA

Friday, January 19 | 8:00AM - 11:15AM
Basic Biology of Inhibitory Receptors
Room: Colorado Ballroom

Speaker 2 of 8
Arlene H. Sharpe, Harvard Medical School, USA
The Role of the PD-1 Pathway in Regulating Immunity

Friday, January 19 | 8:00AM - 11:15AM
Basic Biology of Inhibitory Receptors
Room: Colorado Ballroom

Speaker 3 of 8
Dario A. A. Vignali, University of Pittsburgh School of Medicine, USA
LAG3: Function, Mode of Action and its Impact on Cancer Immunotherapy

Friday, January 19 | 8:00AM - 11:15AM
Basic Biology of Inhibitory Receptors
Room: Colorado Ballroom


Coffee Break

Friday, January 19 | 8:00AM - 11:15AM
Basic Biology of Inhibitory Receptors
Room: Colorado Ballroom

Speaker 5 of 8
Sadna Budhu, Memorial Sloan Kettering Cancer Center, USA
Blockade of Surface-Bound TGF-ß on Regulatory T Cells Abrogates Suppression of Effector T Cell Function in the Tumor Microenvironment

Friday, January 19 | 8:00AM - 11:15AM
Basic Biology of Inhibitory Receptors
Room: Colorado Ballroom

Speaker 6 of 8
Ira Mellman, Genentech, Inc., USA
PD-L1 Blockade and Targeted Therapy

Friday, January 19 | 8:00AM - 11:15AM
Basic Biology of Inhibitory Receptors
Room: Colorado Ballroom

Speaker 7 of 8
Frédéric Duval, University of Montreal, Canada
Short Talk: Notch Signaling Dampens Cd8 T Cell Exhaustion During Chronic Infection

Friday, January 19 | 8:00AM - 11:15AM
Basic Biology of Inhibitory Receptors
Room: Colorado Ballroom

Speaker 8 of 8
Hazem E. Ghoneim, St Jude Children's Research Hospital, USA
Short Talk: Inhibiting Exhaustion-Associated Epigenetic Programs Enhances PD-1 Blockade-Mediated T Cell Rejuvenation

Friday, January 19 | 11:15AM - 5:00PM
On Own for Lunch


Friday, January 19 | 11:15AM - 1:00PM
Poster Setup
Room: Breckenridge Ballroom


Friday, January 19 | 1:00PM - 10:00PM
Poster Viewing
Room: Breckenridge Ballroom


Friday, January 19 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Friday, January 19 | 5:00PM - 7:00PM
Checkpoint Blockade
Room: Colorado Ballroom

Speaker 1 of 5
* Daniel C. Douek, NIAID, National Institutes of Health, USA

Friday, January 19 | 5:00PM - 7:00PM
Checkpoint Blockade
Room: Colorado Ballroom

Speaker 2 of 5
Roberta Zappasodi, Memorial Sloan-Kettering Cancer Center, USA
Non-conventional Immunosuppressive TFH-like CD4+ T Cells Promote Resistance to Immune Checkpoint Blockade Therapy

Friday, January 19 | 5:00PM - 7:00PM
Checkpoint Blockade
Room: Colorado Ballroom

Speaker 3 of 5
Suzanne L. Topalian, Johns Hopkins University School of Medicine, USA
PD-1 Blockade in Virus-Associated Cancers: Intersection of Antitumor Immunity and Infectious Immunity

Friday, January 19 | 5:00PM - 7:00PM
Checkpoint Blockade
Room: Colorado Ballroom

Speaker 4 of 5
E. John Wherry, University of Pennsylvania, USA
T Cell Exhaustion and Immunotherapy

Friday, January 19 | 5:00PM - 7:00PM
Checkpoint Blockade
Room: Colorado Ballroom

Speaker 5 of 5
Rebecca Dookie, University of Manchester, UK
Short Talk: Investigating the Role of Checkpoint Inhibitors in Malaria-Induced T Cell Exhaustion

Friday, January 19 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Breckenridge Ballroom
No registration fees are used to fund alcohol served at this function.

Friday, January 19 | 7:30PM - 10:00PM
Poster Session 3
Room: Breckenridge Ballroom


Saturday, January 20 | 7:00AM - 8:00AM
Breakfast
Room: Breckenridge Ballroom


Saturday, January 20 | 8:00AM - 11:00AM
Targets for T Cells
Room: Colorado Ballroom

Speaker 1 of 7
* Robert A. Seder, NIAID, National Institutes of Health, USA

Saturday, January 20 | 8:00AM - 11:00AM
Targets for T Cells
Room: Colorado Ballroom

Speaker 2 of 7
Robert Thimme, University Medical Center Freiburg, Germany
Impact of Antigen Recognition on T Cell Diversification in Chronic Viral Hepatitis

Saturday, January 20 | 8:00AM - 11:00AM
Targets for T Cells
Room: Colorado Ballroom

Speaker 3 of 7
Pramod K. Srivastava, University of Connecticut School of Medicine, USA
Broadening the View of Mutational Antigens for Cancer Immunotherapy

Saturday, January 20 | 8:00AM - 11:00AM
Targets for T Cells
Room: Colorado Ballroom


Coffee Break

Saturday, January 20 | 8:00AM - 11:00AM
Targets for T Cells
Room: Colorado Ballroom

Speaker 5 of 7
Lélia Delamarre, Genentech, Inc., USA
Determinants of Cancer Neoantigen Immunogenicity

Saturday, January 20 | 8:00AM - 11:00AM
Targets for T Cells
Room: Colorado Ballroom

Speaker 6 of 7
Brendan Bulik-Sullivan, Gritstone Oncology, USA
Short Talk: Antigen Identification for Cancer Immunotherapy by Deep Learning on Tumor HLA Peptides

Saturday, January 20 | 8:00AM - 11:00AM
Targets for T Cells
Room: Colorado Ballroom

Speaker 7 of 7
Thomas Duhen, Agonox, USA
Short Talk: Co-Expression of CD39 and CD103 Identifies Tumor-Reactive CD8 TIL in Human Solid Tumors

Saturday, January 20 | 11:00AM - 5:00PM
On Own for Lunch


Saturday, January 20 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Saturday, January 20 | 5:00PM - 6:15PM
Vaccines to Revive T Cell Responses
Room: Colorado Ballroom

Speaker 1 of 3
* Dario A. A. Vignali, University of Pittsburgh School of Medicine, USA

Saturday, January 20 | 5:00PM - 6:15PM
Vaccines to Revive T Cell Responses
Room: Colorado Ballroom

Speaker 2 of 3
Robert A. Seder, NIAID, National Institutes of Health, USA
Adjuvants for T Cell Vaccines

Saturday, January 20 | 5:00PM - 6:15PM
Vaccines to Revive T Cell Responses
Room: Colorado Ballroom

Speaker 3 of 3
Darrell J. Irvine, Massachusetts Institute of Technology, USA
Boosting T Cells by Getting Vaccines Where They Need to Go

Saturday, January 20 | 6:15PM - 7:00PM
Closing Keynote Address
Room: Colorado Ballroom

Speaker 1 of 2
* Daniel C. Douek, NIAID, National Institutes of Health, USA

Saturday, January 20 | 6:15PM - 7:00PM
Closing Keynote Address
Room: Colorado Ballroom

Speaker 2 of 2
Carl H. June, University of Pennsylvania, USA
Enhancing Engineered T Cell Therapy for Cancer

Saturday, January 20 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Colorado Ballroom


Saturday, January 20 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Breckenridge Ballroom
No registration fees are used to fund alcohol served at this function.

Saturday, January 20 | 8:00PM - 11:00PM
Entertainment
Room: Breckenridge Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Saturday, January 20 | 8:00PM - 11:00PM
Cash Bar
Room: Breckenridge Ballroom


Sunday, January 21 | 10:24AM - 10:24AM
Departure


*Session Chair.

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