The Resolution of Inflammation in Health and Disease

Organizer(s): Catherine Godson, Ira Tabas and Mauro Perretti

Organized in Collaboration with Science Foundation Ireland
Sponsored by Gilead Sciences, Inc.
This activity was supported by an educational grant from Celgene Corporation.

Summary of Meeting:

Inflammation and its resolution are critical to effective host defense and tissue homeostasis. There is a steady increase in the recognition that the effective resolution of inflammation is dynamically regulated through cellular responses to endogenously generated mediators. Ineffective resolution of inflammatory responses likely contributes to the pathogenesis of numerous prevalent conditions including atherosclerosis, arthritis and diabetes. Unresolved chronic inflammation may lead to fibrosis and eventual organ failure. Whereas anti-inflammatory therapeutic approaches are conventional, a growing consensus based on experimental data suggests that an alternative approach may be to mimic agonism of resolution. The aim of this meeting is to enhance our understanding of the molecular mechanisms which underpin the effective resolution of inflammation and how these may fail in aging and disease. Specifically, it seeks to: 1) Encourage dialog between those working in areas where the potential of mimicry of resolution of inflammation might play an under-appreciated role; 2) Consolidate data from diverse mediators that promote resolution; and 3) Contribute to the education and training of graduate students, fellows and faculty. These discussions will provide a multidisciplinary community with insight into physiologic processes underpinning resolution and potential mimicry of such processes for therapeutic gain in pathological conditions.

Scholarship Deadline: November 29 2017

Discounted Abstract Deadline: November 29 2017

Abstract Deadline: December 21 2017

Discounted Registration Deadline: January 18 2018

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We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1 R13 AI136481-01
Funding for this conference was made possible (in part) by 1 R13 AI136481-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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