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Saturday, February 02 | 4:00PM - 8:00PM
Arrival and Registration
Room: Pre Function


Saturday, February 02 | 6:00PM - 8:00PM
Welcome Mixer
Room: Granhall
No registration fees are used to fund alcohol served at this function.

Saturday, February 02 | 6:00PM - 8:00PM
Light Meal - Provided by Granlibakken
Room: Granhall


Sunday, February 03 | 7:00AM - 8:00AM
Breakfast
Room: Granhall


Sunday, February 03 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Mountain/Lake

Speaker 1 of 2
* Silvia Monticelli, Institute for Research in Biomedicine, Switzerland

Sunday, February 03 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Mountain/Lake

Speaker 2 of 2
Stephen T. Smale, University of California, Los Angeles, USA
Bridging the Layers: An Integrative Approach to Transcriptional Regulation of Inflammation

Sunday, February 03 | 9:00AM - 11:45AM
Transcriptional Mechanisms of Immune Cell Development
Room: Mountain/Lake

Speaker 1 of 8
* Sarah Teichmann, Wellcome Sanger Institute, UK

Sunday, February 03 | 9:00AM - 11:45AM
Transcriptional Mechanisms of Immune Cell Development
Room: Mountain/Lake

Speaker 2 of 8
Ellen V. Rothenberg, California Institute of Technology, USA
Transcriptional Control of Lineage Choice in Lymphocyte Commitment

Sunday, February 03 | 9:00AM - 11:45AM
Transcriptional Mechanisms of Immune Cell Development
Room: Mountain/Lake


Coffee Break

Sunday, February 03 | 9:00AM - 11:45AM
Transcriptional Mechanisms of Immune Cell Development
Room: Mountain/Lake

Speaker 4 of 8
Ichiro Taniuchi, RIKEN Center for Integrative Medical Sciences, Japan
Gene Regulation by Local and Long-Range Chromatin Loops during CD4/CD8 Lineage Choice

Sunday, February 03 | 9:00AM - 11:45AM
Transcriptional Mechanisms of Immune Cell Development
Room: Mountain/Lake

Speaker 5 of 8
Amanda G. Fisher, Imperial College London, UK
Epigenetics and Inheritance

Sunday, February 03 | 9:00AM - 11:45AM
Transcriptional Mechanisms of Immune Cell Development
Room: Mountain/Lake

Speaker 6 of 8
Sarah L. Hayward, Emory University, USA
Short Talk: Environmental Cues Regulate Transcriptional Reprogramming of Airway-Resident Memory CD8 T Cells

Sunday, February 03 | 9:00AM - 11:45AM
Transcriptional Mechanisms of Immune Cell Development
Room: Mountain/Lake

Speaker 7 of 8
Jinyong Choi, La Jolla Institute for Immunology, USA
Short Talk: Bcl6 Controls the Follicular Helper T Cell (Tfh) Genetic Program via Inhibition-of-Inhibitor Mechanisms and Exhibits Autoregulation

Sunday, February 03 | 9:00AM - 11:45AM
Transcriptional Mechanisms of Immune Cell Development
Room: Mountain/Lake

Speaker 8 of 8
Marissa C. Franke, University of California, Davis, USA
Short Talk: Role of SET-Like Domain of Blimp-1 in Plasma Cell Differentiation

Sunday, February 03 | 11:45AM - 5:00PM
On Own for Lunch


Sunday, February 03 | 11:45AM - 1:00PM
Poster Setup
Room: Bay


Sunday, February 03 | 1:00PM - 10:00PM
Poster Viewing
Room: Bay


Sunday, February 03 | 2:30PM - 4:30PM
Workshop 1: Innovative Technologies: New Ways to Interrogate
Immune Regulation
Room: Mountain/Lake

Speaker 1 of 7
* Ido Amit, Weizmann Institute, Israel

Sunday, February 03 | 2:30PM - 4:30PM
Workshop 1: Innovative Technologies: New Ways to Interrogate
Immune Regulation
Room: Mountain/Lake

Speaker 2 of 7
Ye Zheng, The Salk Institute for Biological Studies, USA
Novel Foxp3 Regulators Discovered by a Genome-Wide CRISPR Screen

Sunday, February 03 | 2:30PM - 4:30PM
Workshop 1: Innovative Technologies: New Ways to Interrogate
Immune Regulation
Room: Mountain/Lake

Speaker 3 of 7
Huitian Diao, The Scripps Research Institute, USA
Defining Chromatin Regulator Function in CD8 T Cells and in vivo Systems for Inducible and Reversible RNA Interference in Naive T Cells

Sunday, February 03 | 2:30PM - 4:30PM
Workshop 1: Innovative Technologies: New Ways to Interrogate
Immune Regulation
Room: Mountain/Lake

Speaker 4 of 7
Michael Sikora, Stanford University, USA
Select-Sequencing of Clonally Expanded CD8+ T Cells Reveals Limits to Clonal Expansion

Sunday, February 03 | 2:30PM - 4:30PM
Workshop 1: Innovative Technologies: New Ways to Interrogate
Immune Regulation
Room: Mountain/Lake

Speaker 5 of 7
Didi S. Zhu, University of California, San Francisco, USA
A Global Map of RNA-Binding Protein Occupancy Guides Functional Dissection of Post-Transcriptional Regulation of the T Cell Transcriptome

Sunday, February 03 | 2:30PM - 4:30PM
Workshop 1: Innovative Technologies: New Ways to Interrogate
Immune Regulation
Room: Mountain/Lake

Speaker 6 of 7
Deborah R. Winter, Northwestern University, USA
Synovial Macrophages Demonstrate Heterogeneity in their Transcriptional Response to Joint Inflammation in Mouse Models of Arthritis

Sunday, February 03 | 2:30PM - 4:30PM
Workshop 1: Innovative Technologies: New Ways to Interrogate
Immune Regulation
Room: Mountain/Lake

Speaker 7 of 7
Muzaffer Ahmad Kassab, City of Hope, USA
RNA 2’O-Methylation in B Cell Function

Sunday, February 03 | 4:30PM - 5:00PM
Coffee Available
Room: Pre Function


Sunday, February 03 | 5:00PM - 7:00PM
Single Cell Approaches to Immune System Complexity
Room: Mountain/Lake

Speaker 1 of 6
* Matthias Merkenschlager, Imperial College London, UK

Sunday, February 03 | 5:00PM - 7:00PM
Single Cell Approaches to Immune System Complexity
Room: Mountain/Lake

Speaker 2 of 6
Sarah Teichmann, Wellcome Sanger Institute, UK
Immunogenomics One Cell at a Time

Sunday, February 03 | 5:00PM - 7:00PM
Single Cell Approaches to Immune System Complexity
Room: Mountain/Lake

Speaker 3 of 6
Ido Amit, Weizmann Institute, Israel
The Power of ONE: Immunology in the Age of Single Cell Genomics

Sunday, February 03 | 5:00PM - 7:00PM
Single Cell Approaches to Immune System Complexity
Room: Mountain/Lake

Speaker 4 of 6
Muzlifah A. Haniffa, Newcastle University, UK
Functional Heterogeneity of Human Mononuclear Phagocytes

Sunday, February 03 | 5:00PM - 7:00PM
Single Cell Approaches to Immune System Complexity
Room: Mountain/Lake

Speaker 5 of 6
Chrysothemis Brown, Sloan Kettering Institute, USA
Short Talk: Single-Cell Transcriptomics Reveals Novel Dendritic Cell Subsets and their Transcriptional Regulators

Sunday, February 03 | 5:00PM - 7:00PM
Single Cell Approaches to Immune System Complexity
Room: Mountain/Lake

Speaker 6 of 6
Douglas A. Bell, NIEHS, National Institutes of Health, USA
Short Talk: Single Cell RNA Sequencing Reveals Altered Effector CD8+ T Lymphocytes in Smokers

Sunday, February 03 | 7:00PM - 8:00PM
Dinner
Room: Granhall


Sunday, February 03 | 7:30PM - 10:00PM
Poster Session 1
Room: Bay


Sunday, February 03 | 8:00PM - 9:00PM
Social Hour
Room: Bay
No registration fees are used to fund alcohol served at this function.

Monday, February 04 | 7:00AM - 8:00AM
Breakfast
Room: Granhall


Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake

Speaker 1 of 9
* Ellen V. Rothenberg, California Institute of Technology, USA

Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake

Speaker 2 of 9
Anjana Rao, La Jolla Institute for Allergy and Immunology, USA
TET Methylcytosine Oxidases, Immune Responses and Cancer

Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake

Speaker 3 of 9
Yuka Kanno, NIAMS, National Institutes of Health, USA
Genomic Views of Lymphocyte Differentiation and Activation

Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake


Coffee Break

Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake

Speaker 5 of 9
Gioacchino Natoli, Humanitas University, Italy
Access to the Genomic Regulatory Information and the Control of Inflammatory Gene Expression


Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake

Speaker 6 of 9
Christopher K. Glass, University of California, San Diego, USA
Roles of Tissue Environment in Shaping Macrophage Identities in Health and Disease

Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake

Speaker 7 of 9
Diana Hargreaves, The Salk Institute for Biological Studies, USA
Short Talk: Control of Inflammatory Responses by BAF Chromatin Remodeling Complexes

Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake

Speaker 8 of 9
Matthias Merkenschlager, Imperial College London, UK
Short Talk: Quantitative Single Cell Analysis of Macrophage Gene Expression as a Mechanistic Approach to Cohesin-Dependent Regulation of Transcription

Monday, February 04 | 8:00AM - 11:15AM
Transcriptional and Epigenomic Control of Immune Responses
Room: Mountain/Lake

Speaker 9 of 9
Jessica Bouviere, Institut NeuroMyogène, France
Short Talk: Selenoproteins Regulate Macrophage Polarization and Function

Monday, February 04 | 11:15AM - 5:00PM
On Own for Lunch


Monday, February 04 | 11:15AM - 1:00PM
Poster Setup
Room: Bay


Monday, February 04 | 1:00PM - 10:00PM
Poster Viewing
Room: Bay


Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 1 of 9
* Gioacchino Natoli, Humanitas University, Italy

Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 2 of 9
Alejandro Villarino, University of Miami, USA
Transcriptional Programming of T Cell Metabolism Downstream of Cytokine-STAT Signaling

Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 3 of 9
Rahul Roychoudhuri, Babraham Institute, UK
A Treg-Specific Distal Transcriptional Enhancer that Mediates Resistance to Gut Inflammation

Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 4 of 9
Ning Wang, University of California, Los Angeles, USA
On the Identifiability of Gene Regulatory Strategies by Combinations of Signal-Dependent Transcription Factors

Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 5 of 9
Andrew Scott, Memorial Sloan Kettering Cancer Center, USA
Thymocyte Selection-Associated HMG Box Protein TOX is a Master Regulator of Tumor-Specific T Cell Disfunction

Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 6 of 9
Renato Ostuni, Ospedale San Raffaele S.r.l., Italy
Integration of Immune Stimuli Expands the Spectrum of Macrophage Activation States and Identifies Targets for Functional Reprogramming

Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 7 of 9
Mashito Sakai, University of California, San Diego, USA
Deciphering Liver-Environmental Signalling Pathways for Kupffer Cell Identity

Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 8 of 9
Florence Mailhot-Léonard, University of Montreal/University of Chicago, USA
Gene Activation Precedes DNA Demethylation in Response to Infection in Human Dendritic Cells

Monday, February 04 | 2:30PM - 4:30PM
Workshop 2: Transcriptional Control in Physiology and Diseas
e
Room: Mountain/Lake

Speaker 9 of 9
Kelly M. Banks, Weill Cornell Graduate School, USA
Epigenetic Regulation of Neutrophil Development and Neutrophil Extracellular Trap Formation by Tet Enzymes

Monday, February 04 | 4:30PM - 5:00PM
Coffee Available
Room: Pre Function


Monday, February 04 | 5:00PM - 7:00PM
Pathologic Dysregulation of Transcription
Room: Mountain/Lake

Speaker 1 of 6
* Christopher K. Glass, University of California, San Diego, USA

Monday, February 04 | 5:00PM - 7:00PM
Pathologic Dysregulation of Transcription
Room: Mountain/Lake

Speaker 2 of 6
Rab K. Prinjha, GlaxoSmithKline, UK
Drugging Transcription: Progress and Potential for Treating Human Immune Dysfunction

Monday, February 04 | 5:00PM - 7:00PM
Pathologic Dysregulation of Transcription
Room: Mountain/Lake

Speaker 3 of 6
Andrea Schietinger, Memorial Sloan Kettering Cancer Center, USA
Transcription Factors and Epigenetic Programs in Cancer Immunology

Monday, February 04 | 5:00PM - 7:00PM
Pathologic Dysregulation of Transcription
Room: Mountain/Lake

Speaker 4 of 6
Camille Marie Syrett, University of Pennsylvania, USA
Short Talk: A Novel Requirement for Xist RNA-Mediated X Chromosome Inactivation Maintenance in Female-Biased Autoimmunity

Monday, February 04 | 5:00PM - 7:00PM
Pathologic Dysregulation of Transcription
Room: Mountain/Lake

Speaker 5 of 6
Prasida Holla, NIAID, National Institutes of Health, USA
Short Talk: Understanding the Transcriptional Program in Atypical Memory B Cells in Chronic Diseases

Monday, February 04 | 5:00PM - 7:00PM
Pathologic Dysregulation of Transcription
Room: Mountain/Lake

Speaker 6 of 6
Alex Marson, University of California, San Francisco, USA
Reprogramming Human Immune Cell Circuitry

Monday, February 04 | 7:00PM - 8:00PM
Dinner
Room: Granhall


Monday, February 04 | 7:30PM - 10:00PM
Poster Session 2
Room: Bay


Monday, February 04 | 8:00PM - 9:00PM
Social Hour
Room: Bay
No registration fees are used to fund alcohol served at this function.

Tuesday, February 05 | 7:00AM - 8:00AM
Breakfast
Room: Granhall


Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake

Speaker 1 of 9
* Martin Turner, Babraham Institute, UK

Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake

Speaker 2 of 9
K. Mark Ansel, University of California, San Francisco, USA
Mapping RNA Interfaces, Fate and Function in Lymphocytes

Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake

Speaker 3 of 9
Silvia Monticelli, Institute for Research in Biomedicine, Switzerland
Transcriptional and Posttranscriptional Regulation of Human T Lymphocytes

Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake


Coffee Break

Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake

Speaker 5 of 9
Jorge Henao-Mejia, University of Pennsylvania and Children's Hospital of Philadelphia, USA
Long Non-Coding RNAs

Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake

Speaker 6 of 9
Johannes Schwerk, University of Washington, USA
Short Talk: Dual Role of Zinc-Finger Antiviral Protein Splice Variants: Infiltrating Alphavirus Replication Sites and Resolving Antiviral Inflammation

Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake

Speaker 7 of 9
Philippe Bouillet, Walter and Eliza Hall Institute of Medical Research, Australia
Short Talk: Impaired Post-Transcriptional Regulation of TNF Causes Developmental Defects and Inflammatory Diseases

Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake

Speaker 8 of 9
Takuya Uehata, Kyoto University, Japan
Short Talk: Critical Roles of Endonucleases Regnase-1 and Regnase-3 in Early Lymphopoiesis

Tuesday, February 05 | 8:00AM - 11:00AM
Non-Coding Genome and Post-Transcriptional Control in Immuni
ty

Room: Mountain/Lake

Speaker 9 of 9
Anna-Maria Herzner, Genentech, Inc., USA
Short Talk: Dual Protection from Endogenous dsRNA Induced Type-I-IFN Responses by ADAR and hnRNPC

Tuesday, February 05 | 11:00AM - 5:00PM
On Own for Lunch


Tuesday, February 05 | 2:30PM - 4:30PM
Workshop 3: RNA-Mediated Regulation
Room: Mountain/Lake

Speaker 1 of 6
* Vigo Heissmeyer, University of Munich, Germany

Tuesday, February 05 | 2:30PM - 4:30PM
Workshop 3: RNA-Mediated Regulation
Room: Mountain/Lake

Speaker 2 of 6
Davia Blake, University of Pennsylvania, USA
CD28 Regulation of Global Alternative Splicing Changes in Activated Human CD4+ T Cells

Tuesday, February 05 | 2:30PM - 4:30PM
Workshop 3: RNA-Mediated Regulation
Room: Mountain/Lake

Speaker 3 of 6
Wei-Le Wang, City of Hope, USA
MicroRNA-142 Guards against Autoimmunity by Controlling Treg Cell Homeostasis and Function

Tuesday, February 05 | 2:30PM - 4:30PM
Workshop 3: RNA-Mediated Regulation
Room: Mountain/Lake

Speaker 4 of 6
Marianne Doelz, University of Basel, Switzerland
The Surprising Capacity of the miR17-92 microRNA Cluster to Compensate for CD28 Deficiency

Tuesday, February 05 | 2:30PM - 4:30PM
Workshop 3: RNA-Mediated Regulation
Room: Mountain/Lake

Speaker 5 of 6
Matilda Toivakka, University of Edinburgh, UK
Identification of RISC-Associated miRNAs and their Targets during T Cell Activation

Tuesday, February 05 | 2:30PM - 4:30PM
Workshop 3: RNA-Mediated Regulation
Room: Mountain/Lake

Speaker 6 of 6
Osamu Takeuchi, Kyoto University, Japan
Critical Roles of an RNase N4BP1 in Anti-HIV-1 Host Defense and its Control by TCR Signaling

Tuesday, February 05 | 4:30PM - 5:00PM
Coffee Available
Room: Pre Function


Tuesday, February 05 | 5:00PM - 6:45PM
RNA-Binding Proteins and RNA Methylation in Immunity
Room: Mountain/Lake

Speaker 1 of 5
* K. Mark Ansel, University of California, San Francisco, USA

Tuesday, February 05 | 5:00PM - 6:45PM
RNA-Binding Proteins and RNA Methylation in Immunity
Room: Mountain/Lake

Speaker 2 of 5
Vigo Heissmeyer, University of Munich, Germany
Cooperative Regulation of T Cell Fate Decisions by RNA-Binding Proteins

Tuesday, February 05 | 5:00PM - 6:45PM
RNA-Binding Proteins and RNA Methylation in Immunity
Room: Mountain/Lake

Speaker 3 of 5
Monika Wolkers, Sanquin Research, Netherlands
Short Talk: Post-Transcriptional Regulation in T Cell Responses to Infection and Tumors is Time- and Context-Dependent

Tuesday, February 05 | 5:00PM - 6:45PM
RNA-Binding Proteins and RNA Methylation in Immunity
Room: Mountain/Lake

Speaker 4 of 5
Fraser Soares, Canada
Short Talk: CRISPR/Cas9 Screening Identifies the m6A Methyltransferase METTL3 as a Regulator of PDL-1

Tuesday, February 05 | 5:00PM - 6:45PM
RNA-Binding Proteins and RNA Methylation in Immunity
Room: Mountain/Lake

Speaker 5 of 5
Martin Turner, Babraham Institute, UK
An Indispensable Role for Polypyrimidine Tract Binding Proteins in B Cell Development

Tuesday, February 05 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Mountain/Lake


Tuesday, February 05 | 7:00PM - 8:00PM
Dinner
Room: Granhall


Tuesday, February 05 | 7:00PM - 8:00PM
Social Hour
Room: Granhall
No registration fees are used to fund alcohol served at this function.

Tuesday, February 05 | 8:00PM - 11:00PM
Entertainment
Room: Granhall
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Tuesday, February 05 | 8:00PM - 11:00PM
Cash Bar
Room: Granhall


Wednesday, February 06 | 10:24AM - 10:24AM
Departure


*Session Chair.

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