Lipidomics and Functional Metabolic Pathways in Disease
Organizer(s): Sarah Spiegel, Charles N. Serhan and Valerie B. O'DonnellDate: March 31 - April 04, 2019
Location: Steamboat Grand, Steamboat Springs, CO, USA
Recently, our understanding of lipid metabolism has significantly advanced, at least in part through applying state-of-the-art lipidomic mass spectrometry approaches to cellular, cohort and animal models. A large body of evidence now exists demonstrating that bioactive lipids play key roles in regulation of biological processes important for health and disease. However, lipidomics also reveals major gaps in our knowledge, highlighting the enormous numbers and functional and structural diversity of bioactive lipids, their interactions, spatial and temporal changes and the complicated systems biology of lipid metabolism. This Keystone Symposia conference covers areas of bioactive lipid research that have been particularly impacted by these new technologies, which may have the potential to transform precision medicine. The conference covers recent progress and perspectives in the study of bioactive lipid metabolic pathways, how these interconnect and are cross-regulated, and their involvement in the regulation of disease. The conference brings together outstanding senior and junior scientists with expertise in functions of bioactive lipids as well as those with a background in mass spectrometry lipidomics, structural biology and systems biology of lipids. Goals and anticipated outcomes are: 1) To summarize new approaches and state-of-the-art mass spectrometry technology. combined with informatics and statistics, in bioactive lipid research and to gain broad understanding of their limitations and potential application to precision medicine; 2) To acquire a broader understanding of how lipidomics can be integrated with proteomics/genomics and other ‘omics technologies to develop a systems-wide view of the lipidome; 3) To gain new knowledge in spatial and temporal interactions of bioactive lipids in cellular and subcellular systems, to better understand their functions in health and diseases; and 4) To present recent findings on the biological importance of newly discovered lipids and their roles in immunity and inflammation.
Scholarship Deadline: December 11 2018
Discounted Abstract Deadline: December 11 2018
Abstract Deadline: December 19 2018
Discounted Registration Deadline: January 30 2019
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
We gratefully acknowledge the generous grant for this conference provided by:National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK120257-01
Funding for this conference was made possible (in part) by 1R13DK120257-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.