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Web Desc
Proteomics and its Application to Translational and Precision Medicine
Organizer(s): Matthias Mann, Emma K. Lundberg, Albert J.R. Heck and Mathias Uhlén
Date: April 07 - 11, 2019
Location: Clarion Hotel Sign, Stockholm, Sweden
Organized in collaboration with Knut and Alice Wallenberg Foundation
and Science for Life Laboratory

Sponsored by BioLegend, Inc., Novo Nordisk A/S, Roche and Thermo Fisher Scientific Inc.
Summary of Meeting:
Proteomics methods have advanced tremendously in just the last few years. Apart from increasingly powerful mass-spectrometric methods, global antibody based methods, chemical biology approaches and genetics/genomics approaches and their combinations are now offering a rich toolbox to study the proteome in many different dimensions. Given this background and the recent completion of in depth proteomes, it is now time to apply proteomics in a more translational context to patient derived primary cells, organoids, xenograft models and indeed to the clinic. MS based proteomics, in particular, interaction proteomics in combination with chemical and structural proteomics, is making crucial contributions to drug development and deeper molecular understanding of disease mechanisms. The analysis of post-translational modifications has become orders of magnitude more comprehensive, quantitative and accessible, now enabling in-vivo and time-resolved studied of a large range of signaling processes. In combination with genome engineering, this opens up entirely new perspectives in precision investigation of deregulated signaling processes in models of oncology, immunology or metabolic diseases. Finally, proteomic profiling of body fluids has matured to a degree that it enables informative ‘phenotyping’ of humans in health and disease, supporting ‘wellness’ and patient stratification/biomarker studies.
Scholarship Deadline: December 12 2018
Discounted Abstract Deadline: December 12 2018
Abstract Deadline: January 9 2019
Discounted Registration Deadline: February 6 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
BioLegend, Inc.Knut and Alice Wallenberg FoundationNovo Nordisk A/SRocheScience for Life LaboratoryThermo Fisher Scientific Inc.
We gratefully acknowledge additional support from these exhibitors at this conference:
PharmaFluidics
We gratefully acknowledge additional support for this conference from:
ACS Chemical BiologyACS Pharmacology & Translational ScienceeLifeMolecular & Cellular Proteomics
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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