Signal Dynamics and Signal Integration in Development and Disease
joint with Cellular Plasticity: Reprogramming, Regeneration and Metaplasia
Organizer(s): Nicolas Tapon, Liliana Attisano and Raphael KopanDate: January 27 - 31, 2019
Location: Keystone Resort, Keystone, CO, USA
The discovery and study of the major developmental signaling pathways (Notch, Hh, Wnt, RTK) has illuminated how patterning and growth are controlled in metazoans. These pathways are reiteratively used during development and adult life, acting to maintain stem cells and direct tissue repair and regeneration. When they are disrupted, cancer develops. This conference embraces recent progress in quantitative biology, mathematical modelling, single cell analysis and intravital imaging. It also presents a major opportunity to bring together knowledge from developmental systems with adult homeostasis, regeneration and cancer, as well as to elucidate how different developmental signals are integrated to influence cellular decision-making processes. The pairing with the conference on Cellular Plasticity: Reprogramming, Regeneration, and Metaplasia enables an in-depth exploration of the parallels between plasticity/pluripotency in development, regeneration and disease. In summary, the conference aims to: 1) Explore the commonalities between signaling in development, regeneration, and homeostasis, 2) Leverage quantitative, single cell and systems biology to study the dynamics and integration of developmental signaling across scales, and 3) Highlight how perturbations in developmental pathways cause diseases such as cancer.
Scholarship Deadline: October 17 2018
Discounted Abstract Deadline: October 17 2018
Abstract Deadline: October 25 2018
Discounted Registration Deadline: November 28 2018
We gratefully acknowledge the generous grant for this conference provided by:Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Grant No. 1 R13 HD096834-01
Funding for this conference was made possible (in part) by 1 R13 HD096834-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.