Innate Immune Receptors: Roles in Immunology and Beyond

Organizer(s): Jenny P.Y. Ting, Shie-Liang Edmond Hsieh, Fu-Tong Liu, Michael Gale, Jr. and Siamon Gordon

Developed in collaboration with Academia Sinica

Sponsored by BioLegend, Inc. and Genentech, Inc.

Summary of Meeting:

Innate immune receptors include a plethora of membrane-associated proteins as well as intracellular receptors that directly bind or sense the presence of pathogen-associated molecular patterns (PAMPs). The importance of innate immune receptors was first appreciated in infectious diseases and autoinflammatory disorders, but it is now clear that their roles extend beyond innate immunology. The crucial roles of these receptors in many clinically relevant fields, and their newly documented role in non-immune cells, underscore their importance in biologic processes and diseases. This conference will address the ligands and signaling mechanisms of a diverse set of innate immune receptors as well as the profound impacts of innate immune receptors on the microbiome, which in turn has impacts on multiple organ systems. The program includes discussion of the intrinsic functions of innate immune receptors within adaptive immune cells, non-immune cells such as epithelial and endothelial cells, and their roles in cancer and stem cells. The pleitrophic effects of this important receptor class have far-reaching consequences for critical biological processes such as cancer cell death and signaling, DNA damage, stress response, stem cell proliferation/differentiation, vaccine adjuvanticity, age-related dementia, metabolic disorders and microbiome balance. By the nature of the topic, this conference brings together an interdisciplinary group of investigators to catalyze cross-fertilization of ideas and stimulate important medical advances.

Scholarship Deadline: November 27 2018

Discounted Abstract Deadline: November 27 2018

Abstract Deadline: December 11 2018

Discounted Registration Deadline: January 17 2019

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

Academia Sinica

We gratefully acknowledge additional support from these exhibitors at this conference:

We gratefully acknowledge additional support for this conference from:

China Medical University

Chinese Society of Immunology

National Health Research Institutes

National Yang-Ming University

Taiwan Rheumatology Association

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Dynavax Technologies Corporation

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI142987-01
Funding for this conference was made possible (in part) by 1R13AI142987-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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