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Friday, March 15 | 4:00PM - 8:00PM
Arrival and Registration
Room: Fureria


Friday, March 15 | 6:00PM - 8:00PM
Welcome Mixer
Room: Arsenale
No registration fees are used to fund alcohol served at this function.

Saturday, March 16 | 8:00AM - 8:30AM
Poster Setup
Room: Arsenale


Saturday, March 16 | 8:30AM - 6:00PM
Poster Viewing
Room: Arsenale


Saturday, March 16 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Basilica

Speaker 1 of 2
* Erika L. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany

Saturday, March 16 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Basilica

Speaker 2 of 2
Charles Swanton, Francis Crick Institute, UK
Chromosomal Instability and Genome Plasticity in Cancer Evolution, Immune Evasion and Metastasis

Saturday, March 16 | 9:30AM - 12:00PM
Interactions via the Tumor Microenvironment
Room: Basilica

Speaker 1 of 7
* Sarah-Maria Fendt, VIB Leuven, Belgium

Saturday, March 16 | 9:30AM - 12:00PM
Interactions via the Tumor Microenvironment
Room: Basilica

Speaker 2 of 7
Massimiliano Mazzone, KU Leuven – VIB, Belgium
Immunometabolism in Cancer and Other Diseases

Saturday, March 16 | 9:30AM - 12:00PM
Interactions via the Tumor Microenvironment
Room: Basilica


Coffee Break

Saturday, March 16 | 9:30AM - 12:00PM
Interactions via the Tumor Microenvironment
Room: Basilica

Speaker 4 of 7
Shizhen Emily Wang, University of California, San Diego, USA
Secreted miRNAs Reprogram Metabolism in the Tumor Niche

Saturday, March 16 | 9:30AM - 12:00PM
Interactions via the Tumor Microenvironment
Room: Basilica

Speaker 5 of 7
Karen H. Vousden, Francis Crick Institute, UK
ROS Regulation and Cancer Progression

Saturday, March 16 | 9:30AM - 12:00PM
Interactions via the Tumor Microenvironment
Room: Basilica

Speaker 6 of 7
Samuel F. Bakhoum, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Chromosomal Instability Promotes Metastasis through a Cytosolic DNA Response and Modulation of the Immune Microenvironment

Saturday, March 16 | 9:30AM - 12:00PM
Interactions via the Tumor Microenvironment
Room: Basilica

Speaker 7 of 7
Li Yang, NCI, National Institutes of Health, USA
Short Talk: DNMT3B Induction at Distant Site Promotes Breast Cancer Metastasis through Epigenetic Reprogramming

Saturday, March 16 | 12:00PM - 1:00PM
Lunch
Room: Arsenale


Saturday, March 16 | 1:00PM - 3:30PM
Poster Session 1
Room: Arsenale


Saturday, March 16 | 3:30PM - 4:00PM
Coffee Available
Room: Arsenale


Saturday, March 16 | 4:00PM - 6:00PM
Mitochondria and Oxidative Stress in Cancer Metastasis and I
mmunity

Room: Basilica

Speaker 1 of 6
* Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA

Saturday, March 16 | 4:00PM - 6:00PM
Mitochondria and Oxidative Stress in Cancer Metastasis and I
mmunity

Room: Basilica

Speaker 2 of 6
Erika L. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany
Mitochondrial Integrity Regulated by FABP5 is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

Saturday, March 16 | 4:00PM - 6:00PM
Mitochondria and Oxidative Stress in Cancer Metastasis and I
mmunity

Room: Basilica

Speaker 3 of 6
Marcia C. Haigis, Harvard Medical School, USA
New Functions for Metabolic Byproducts in the Tumor Microenvironment

Saturday, March 16 | 4:00PM - 6:00PM
Mitochondria and Oxidative Stress in Cancer Metastasis and I
mmunity

Room: Basilica

Speaker 4 of 6
Russell G. Jones, Van Andel Research Institute, USA
Essential Nutrients for Effector T Cell Expansion

Saturday, March 16 | 4:00PM - 6:00PM
Mitochondria and Oxidative Stress in Cancer Metastasis and I
mmunity

Room: Basilica

Speaker 5 of 6
Zachary T. Schafer, University of Notre Dame, USA
Short Talk: Resistance to PD-1 Checkpoint Inhibitors Is Associated with Defective RIPK1-Mediated Mitophagy

Saturday, March 16 | 4:00PM - 6:00PM
Mitochondria and Oxidative Stress in Cancer Metastasis and I
mmunity

Room: Basilica

Speaker 6 of 6
Alexei Vazquez, CRUK Beatson Institute, UK
Short Talk: Formate Links Glycolysis to Oxidative Phosphorylation

Saturday, March 16 | 6:00PM - 6:00PM
On Own for Dinner
No registration fees are used to fund alcohol served at this function.

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica

Speaker 1 of 9
* Georgia Hatzivassiliou, Genentech, Inc., USA

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica

Speaker 2 of 9
Ralph J. DeBerardinis, University of Texas Southwestern Medical Center, USA
Metabolic Enablers of Cancer Progression

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica

Speaker 3 of 9
Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA
Microenvironmental Determinants of Tumor Metabolism

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica


Coffee Break

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica

Speaker 5 of 9
Giuseppe Matarese, Università degli Studi di Napoli Federico II, Italy
Regulatory T Cells as Suppressors of Anti-Tumor Immunity

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica

Speaker 6 of 9
Iannis Aifantis, New York University School of Medicine, USA
Mapping the Bone Marrow Microenvironment in Single Cell Resolution

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica

Speaker 7 of 9
Fabio Grassi, Institute for Research in Biomedicine, Switzerland
Short Talk: Senescence Induction by the ATP-Gated P2X7 Receptor Limits T Cell Effector Response in the Tumor Microenvironment

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica

Speaker 8 of 9
Paula D. Bos, Virginia Commonwealth University, USA
Short Talk: Regulatory T Cells Promote Breast Cancer Progression and Metastasis by Functional Reprogramming of Bone Marrow-Derived Cell Populations

Sunday, March 17 | 8:30AM - 11:45AM
Cancer and Immunity in the Tumor Microenvironment
Room: Basilica

Speaker 9 of 9
Zachary Bacigalupa, Vanderbilt University Medical Center, USA
Short Talk: Targeting ACSS2 Inhibits HIF-2a Signaling in ccRCC and Promotes Favorable T Cell Characteristics Immune Response in ccRCC

Sunday, March 17 | 11:45AM - 4:00PM
On Own for Lunch


Sunday, March 17 | 11:45AM - 1:00PM
Poster Setup
Room: Arsenale


Sunday, March 17 | 1:00PM - 10:00PM
Poster Viewing
Room: Arsenale


Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 1 of 9
* Julian J. Lum, British Columbia Cancer Agency, Canada

Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 2 of 9
Ho-Young Lee, Seoul National University, South Korea
The Interplay between Slow-Cycling Chemoresistant Cancer Cells and Fibroblasts in Tumor Microenvironment Mediates Tumor Recurrence in Lung Cancer

Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 3 of 9
Julianna Blagih, Francis Crick Institute, UK
Loss of p53 in Tumor Cells Promotes Immune-Tolerance through Modulation of the Innate and Adaptive Immune Responses

Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 4 of 9
Medhi Wangpaichitr, Miami VA Hospital, USA
Kynurenine Metabolism in Cisplatin-Resistant Lung Cancer

Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 5 of 9
Nuzhat Ahmed, Fiona Elsey Cancer Research Institute, Australia
Metabolic and Immune Regulatory Signatures in Chemoresistant Ovarian Cancer Stem Cells

Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 6 of 9
David R. Soto-Pantoja, Wake Forest School of Medicine, USA
Metabolic Endpoints as Biomarkers of Immune Checkpoint Therapy Response

Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 7 of 9
Chia-Ning Shen, Academia Sinica, Taiwan
Mitochondrial OXPHOS Activity Is Required for Lung Metastatic Colonization of Pancreatic Cancer

Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 8 of 9
Madhusudhanan Sukumar, NCI, National Institutes of Health, USA
Mitochondrial Uncoupling Protein 2 (UCP2) Regulates T Cell Longevity and Anti-Tumor Function

Sunday, March 17 | 1:30PM - 3:30PM
Workshop
Room: Basilica

Speaker 9 of 9
Jing Fan, University of Wisconsin-Madison, USA
Two-Stage Remodeling of Mitochondrial Metabolism in Macrophages Over a Course of Immune Response

Sunday, March 17 | 3:30PM - 4:00PM
Coffee Available
Room: Arsenale


Sunday, March 17 | 4:00PM - 6:00PM
Metastasis, Tumor Vessels and Immunity
Room: Basilica

Speaker 1 of 6
* Massimiliano Mazzone, KU Leuven – VIB, Belgium

Sunday, March 17 | 4:00PM - 6:00PM
Metastasis, Tumor Vessels and Immunity
Room: Basilica

Speaker 2 of 6
Sarah-Maria Fendt, VIB Leuven, Belgium
Cancer Metabolism during Metastasis Formation

Sunday, March 17 | 4:00PM - 6:00PM
Metastasis, Tumor Vessels and Immunity
Room: Basilica

Speaker 3 of 6
Michael Potente, Max Planck Institute for Heart and Lung Research, Germany
Metabolic Activity and Growth State in the Vascular Endothelium

Sunday, March 17 | 4:00PM - 6:00PM
Metastasis, Tumor Vessels and Immunity
Room: Basilica

Speaker 4 of 6
Bin-Zhi Qian, University of Edinburgh, UK
Macrophage Heterogeneity in Breast Cancer Metastasis

Sunday, March 17 | 4:00PM - 6:00PM
Metastasis, Tumor Vessels and Immunity
Room: Basilica

Speaker 5 of 6
Sophia Y. Lunt, Michigan State University, USA
Short Talk: Sialic Acid Metabolism Is a Key Driver of Breast Cancer Metastasis

Sunday, March 17 | 4:00PM - 6:00PM
Metastasis, Tumor Vessels and Immunity
Room: Basilica

Speaker 6 of 6
Andreas Fischer, German Cancer Research Center, Germany
Short Talk: Angiocrine Signals Promote Metastasis

Sunday, March 17 | 6:00PM - 7:00PM
Social Hour with Lite Bites
Room: Arsenale
No registration fees are used to fund alcohol served at this function.

Sunday, March 17 | 6:30PM - 9:00PM
Poster Session 2
Room: Arsenale


Monday, March 18 | 8:00AM - 8:30AM
Poster Setup
Room: Arsenale


Monday, March 18 | 8:30AM - 4:00PM
Poster Viewing
Room: Arsenale


Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica

Speaker 1 of 9
* Giuseppe Matarese, Università degli Studi di Napoli Federico II, Italy

Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica

Speaker 2 of 9
Katya Marjon, Agios Pharmaceuticals, USA
Therapeutics Targets in Cancer Metabolism

Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica

Speaker 3 of 9
Tim F. Greten, NCI, National Institutes of Health, USA
Targeting the Inflammation – Cancer Axis

Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica


Coffee Break

Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica

Speaker 5 of 9
Georgia Hatzivassiliou, Genentech, Inc., USA
Dissecting the Impact of NRF2 Activation on Lung Adenocarcinoma Biology, Immune Contexture and Patient Outcomes

Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica

Speaker 6 of 9
Gabriele A.I. Bergers, University of Leuven, Belgium
Constructing Tumor Vessels to Enhance Immunity

Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica

Speaker 7 of 9
Julian J. Lum, British Columbia Cancer Agency, Canada
Short Talk: Understanding the Metabolome of Human TIL for Cancer Immunotherapy

Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica

Speaker 8 of 9
Fabricio Loayza-Puch, German Cancer Research Center, Germany
Short Talk: Targeting Proline Availability in Metastatic Breast Cancer

Monday, March 18 | 8:30AM - 11:45AM
Therapeutic Strategies for Metabolism and Immune Modulation
Room: Basilica

Speaker 9 of 9
Gus Zeiner, Chimera Bioengineering, USA
Short Talk: A Metabolism-Triggered, Localized Payload Delivery System for T Cell Therapies

Monday, March 18 | 11:45AM - 1:00PM
Lunch
Room: Arsenale


Monday, March 18 | 1:00PM - 3:30PM
Poster Session 3
Room: Arsenale


Monday, March 18 | 3:30PM - 4:00PM
Coffee Available
Room: Arsenale


Monday, March 18 | 4:00PM - 6:00PM
Stem Cells in Inflammation, Cancer and Metastasis
Room: Basilica

Speaker 1 of 6
* Iannis Aifantis, New York University School of Medicine, USA

Monday, March 18 | 4:00PM - 6:00PM
Stem Cells in Inflammation, Cancer and Metastasis
Room: Basilica

Speaker 2 of 6
Elaine V. Fuchs, Rockefeller University, USA
Skin Stem Cells in Inflammation and Cancer

Monday, March 18 | 4:00PM - 6:00PM
Stem Cells in Inflammation, Cancer and Metastasis
Room: Basilica

Speaker 3 of 6
Mohamed Bentires-Alj, University of Basel, University Hospital Basel, Switzerland
Cancer Targeted Therapy and Tumor Heterogeneity: Act Locally, Think Globally

Monday, March 18 | 4:00PM - 6:00PM
Stem Cells in Inflammation, Cancer and Metastasis
Room: Basilica

Speaker 4 of 6
Robert A. Weinberg, Massachusetts Institute of Technology, USA
The EMT, Cancer and the Stem Cell State

Monday, March 18 | 4:00PM - 6:00PM
Stem Cells in Inflammation, Cancer and Metastasis
Room: Basilica

Speaker 5 of 6
Guy Roukens, University Medical Center Utrecht, Netherlands
Short Talk: SOX4 is Required for Regulation of Angiogenesis and Tumor Stem Cells in Breast Cancer

Monday, March 18 | 4:00PM - 6:00PM
Stem Cells in Inflammation, Cancer and Metastasis
Room: Basilica

Speaker 6 of 6
Binwu Tang, NCI, National Institutes of Health, USA
Short Talk: Elucidating the Role of Breast Cancer Stem Cells in Early Metastasis through Direct Visualization and Quantitation

Monday, March 18 | 6:00PM - 6:00PM
On Own for Dinner
No registration fees are used to fund alcohol served at this function.

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica

Speaker 1 of 9
* Michael Potente, Max Planck Institute for Heart and Lung Research, Germany

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica

Speaker 2 of 9
M. Celeste Simon, University of Pennsylvania, USA
Metabolic Symbioses in the Tumor Micorenvironment

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica

Speaker 3 of 9
Sohail F. Tavazoie, Rockefeller University, USA
Innate Immune and Metabolic Regulation of Metastatic Progression

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica


Coffee Break

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica

Speaker 5 of 9
Wanjun Chen, NIDCR, National Institutes of Health, USA
D-mannose in Autoimmunity and Cancer

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica

Speaker 6 of 9
Arkaitz Carracedo, Center for Cooperative Research in Biosciences, Spain
Signaling and Metabolic Plasticity in the Process of Prostate Cancer Metastasis

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica

Speaker 7 of 9
Ana Patricia Gomes, Weill Cornell Medicine, USA
Short Talk: Age-Induced Methylmalonic Acid Accumulation Promotes Cancer Progression and Metastasis Formation

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica

Speaker 8 of 9
Emily Jane Kay, Beatson Institute, UK
Short Talk: Pyruvate Dehydrogenase: The Key to Epigenetic Regulation of Mammary CAFs

Tuesday, March 19 | 8:30AM - 11:45AM
Metabolism Meets Cancer Metastasis
Room: Basilica

Speaker 9 of 9
Yulia Panina, Francis Crick Institute, UK
Short Talk: Using Mass Spectrometry Imaging to Identify Metabolic Adaptations during Metastasis of MYC-Driven Tumors

Tuesday, March 19 | 11:45AM - 5:00PM
On Own for Lunch


Tuesday, March 19 | 3:30PM - 4:00PM
Coffee Available
Room: Arsenale


Tuesday, March 19 | 4:00PM - 5:45PM
Commensal Interactions: Implications for Immunity and Cancer
Room: Basilica

Speaker 1 of 4
* Russell G. Jones, Van Andel Research Institute, USA

Tuesday, March 19 | 4:00PM - 5:45PM
Commensal Interactions: Implications for Immunity and Cancer
Room: Basilica

Speaker 2 of 4
Filipe J. Gomes Cabreiro, Imperial College London, UK
Host-Microbe-Drug-Nutrient Interactions- A Holistic Approach for Cancer Treatment

Tuesday, March 19 | 4:00PM - 5:45PM
Commensal Interactions: Implications for Immunity and Cancer
Room: Basilica

Speaker 3 of 4
Jennifer Ann Wargo, University of Texas MD Anderson Cancer Center, USA
The Gut Microbiome and PD-1 Therapy in Melanoma

Tuesday, March 19 | 4:00PM - 5:45PM
Commensal Interactions: Implications for Immunity and Cancer
Room: Basilica

Speaker 4 of 4
Nicholas Chia, Mayo Clinic, USA
Distinct Microbes, Metabolites and Ecologies Define the Microbiome in Deficient and Proficient Mismatch Repair Colorectal Cancers

Tuesday, March 19 | 5:45PM - 6:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Basilica


Tuesday, March 19 | 6:00PM - 7:00PM
Social Hour with Lite Bites
Room: Arsenale
No registration fees are used to fund alcohol served at this function.

Tuesday, March 19 | 7:00PM - 10:00PM
Entertainment
Room: Arsenale
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Tuesday, March 19 | 8:00PM - 10:00PM
Cash Bar
Room: Arsenale


Wednesday, March 20 | 10:24AM - 10:24AM
Departure


*Session Chair.

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