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Web Desc
Unraveling the Secrets of Kidney Disease
joint with Diabetes: Innovations, Outcomes and Personalized Therapies
Organizer(s): Katalin Susztak, Caroline Fox and Masaomi Nangaku
Date: March 03 - 07, 2019
Location: Whistler Conference Centre, Whistler, BC, Canada
Sponsored by Akebia Therapeutics, Bayer AG and Vertex Pharmaceuticals Incorporated
Summary of Meeting:
Approximately one in 11 people in the world suffers from kidney disease. The incidence of kidney disease is increasing, especially in the developing world. This issue was recently reviewed and emphasized in a Lancet article (Global Health Atlas). Acute and chronic kidney disease is associated with a highly significant increase in cardiovascular death. Chronic kidney disease (CKD) represents a leading cause of death in the United States. There is no cure for this disease, with current treatment strategies relying on blood pressure control through blockade of the renin-angiotensin system. Such approaches only delay the development of end-stage kidney disease and can be associated with serious side effects. Recent identification of several novel mechanisms contributing to CKD development - including vascular changes, loss of podocytes and renal epithelial cells, matrix deposition, inflammation and metabolic dysregulation - has revealed new potential therapeutic approaches for CKD. This conference will review clinical and observational studies in the kidney disease area, highlight recent advances in basic biology of kidney and kidney disease, assess emerging strategies and agents for CKD treatment, and discuss major obstacles in drug development. The conference will also encourage collaborations among clinicians and researchers from academic institutes and pharmaceutical laboratories to accelerate innovation in this field. There has not been a conference in the area in kidney disease that brings together clinicians, basic scientists and industry to foster collaboration. Small focused conferences have been organized by the International Society of Nephrology, but these conferences are limited to a single special topic. Furthermore, more than half of kidney disease is caused by diabetes; pairing the conference with a conference focused on diabetes affords the opportunity to understand the role of diabetes in the development of kidney complications.
Scholarship Deadline: November 19 2018
Discounted Abstract Deadline: November 19 2018
Abstract Deadline: December 19 2018
Discounted Registration Deadline: January 11 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Akebia TherapeuticsBayer AGVertex Pharmaceuticals Incorporated
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Boehringer Ingelheim Pharmaceuticals, Inc.

Regeneron Genetics Center, LLC
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK120137-01
Funding for this conference was made possible (in part) by 1R13DK120137-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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