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Sunday, January 19 | 4:00PM - 8:00PM
Arrival and Registration
Room: British/Columbia Foyer


Sunday, January 19 | 6:00PM - 8:00PM
Welcome Mixer
Room: British/Columbia Foyer
No registration fees are used to fund alcohol served at this function.

Monday, January 20 | 7:30AM - 8:30AM
Breakfast
Room: Pacific Ballroom


Monday, January 20 | 8:00AM - 8:30AM
Poster Setup
Room: Pacific Ballroom


Monday, January 20 | 8:30AM - 7:00PM
Poster Viewing
Room: Pacific Ballroom


Monday, January 20 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: British Ballroom

Speaker 1 of 3
* Thaddeus S. Stappenbeck, Cleveland Clinic, USA

Monday, January 20 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: British Ballroom

Speaker 2 of 3
* Linda G. Griffith, Massachusetts Institute of Technology, USA

Monday, January 20 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: British Ballroom

Speaker 3 of 3
Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA
Modeling of Human Diseases in Mouse - Human Chimeras

Monday, January 20 | 9:30AM - 12:00PM
Modeling Pathogen Interactions with Organoids
Room: British Ballroom

Speaker 1 of 8
* Thaddeus S. Stappenbeck, Cleveland Clinic, USA

Monday, January 20 | 9:30AM - 12:00PM
Modeling Pathogen Interactions with Organoids
Room: British Ballroom

Speaker 2 of 8
* Linda G. Griffith, Massachusetts Institute of Technology, USA

Monday, January 20 | 9:30AM - 12:00PM
Modeling Pathogen Interactions with Organoids
Room: British Ballroom

Speaker 3 of 8
Mary K. Estes, Baylor College of Medicine, USA
Human Intestinal Organoids: Transformative Tools to Study Gastrointestinal Infections

Monday, January 20 | 9:30AM - 12:00PM
Modeling Pathogen Interactions with Organoids
Room: British Ballroom


Coffee Break

Monday, January 20 | 9:30AM - 12:00PM
Modeling Pathogen Interactions with Organoids
Room: British Ballroom

Speaker 5 of 8
L. David Sibley, Washington University School of Medicine, USA
New Models of Cryptosporidium Culture in Primary Intestinal Epithelial Cells

Monday, January 20 | 9:30AM - 12:00PM
Modeling Pathogen Interactions with Organoids
Room: British Ballroom

Speaker 6 of 8
Melanie M. Ott, Gladstone Institutes, USA
Hepatitis C Virus (HCV) Infects and Perturbs Liver Stem Cells

Monday, January 20 | 9:30AM - 12:00PM
Modeling Pathogen Interactions with Organoids
Room: British Ballroom

Speaker 7 of 8
Seongmi Kim, Washington University in St. Louis, USA
Short Talk: Primary Cells Isolated from Mice with Prior UTI History Revealed that Bladder Epithelial Stem Cells Undergo Epigenetic Changes Upon Chronic Infection

Monday, January 20 | 9:30AM - 12:00PM
Modeling Pathogen Interactions with Organoids
Room: British Ballroom

Speaker 8 of 8
Mouhita Humayun, University of Wisconsin-Madison, USA
Short Talk: Immune Cell Response to Toxoplasma gondii Infection in a 3D Organotypic Intestinal Model

Monday, January 20 | 12:00PM - 12:45PM
Lunch
Room: Pacific Ballroom


Monday, January 20 | 12:00PM - 2:30PM
Poster Session 1
Room: Pacific Ballroom


Monday, January 20 | 2:30PM - 4:30PM
Workshop 1
Room: British Ballroom

Speaker 1 of 8
* Mary K. Estes, Baylor College of Medicine, USA

Monday, January 20 | 2:30PM - 4:30PM
Workshop 1
Room: British Ballroom

Speaker 2 of 8
Joannie Allaire, University of British Columbia, Canada
Defining the Roles of IL37/SIGIRR in Regulating Innate Signaling by Intestinal Epithelial Cells using Enteroids

Monday, January 20 | 2:30PM - 4:30PM
Workshop 1
Room: British Ballroom

Speaker 3 of 8
Carolina Arias, University of California, Santa Barbara, USA
Retinal Organoids as Physiological Proxies for the Study of Ocular Viral Infections

Monday, January 20 | 2:30PM - 4:30PM
Workshop 1
Room: British Ballroom

Speaker 4 of 8
Ka-Yee Grace Choi, University of British Columbia, Canada
Effects of Host Defence Peptides on Pseudomonas aeruginosa Lung Infections using Organoids and Mice

Monday, January 20 | 2:30PM - 4:30PM
Workshop 1
Room: British Ballroom

Speaker 5 of 8
Alyssa Fasciano, Tufts University School of Medicine, USA
Breaching the Barrier: Investigating Selective Yersinia Entry into M Cells using Human Ileal Enteroid Monolayers

Monday, January 20 | 2:30PM - 4:30PM
Workshop 1
Room: British Ballroom

Speaker 6 of 8
Grace Hudson, University of Calgary, Canada
Understanding the Infection Dynamics of Mycobacterium Paratuberculosis (MAP)

Monday, January 20 | 2:30PM - 4:30PM
Workshop 1
Room: British Ballroom

Speaker 7 of 8
Dasja Pajkrt, Amsterdam University Medical Center, Netherlands
Studies on Picornavirus Infection using Human Organoids

Monday, January 20 | 2:30PM - 4:30PM
Workshop 1
Room: British Ballroom

Speaker 8 of 8
Annika Niehrs, Heinrich-Pette Institut, Germany
Hepatocyte Organoids as a Model System to Study Immune Cell Recognition of HBV-Infected Hepatocytes

Monday, January 20 | 4:30PM - 5:00PM
Coffee Available
Room: British/Columbia Foyer


Monday, January 20 | 5:00PM - 7:00PM
Modeling Immunity into Organoid Systems
Room: British Ballroom

Speaker 1 of 4
* Charles E. Whitehurst, Boehringer Ingelheim Pharmaceuticals, Inc., USA

Monday, January 20 | 5:00PM - 7:00PM
Modeling Immunity into Organoid Systems
Room: British Ballroom

Speaker 2 of 4
Senthil K. Muthuswamy, Harvard Medical School, USA
Stem Cell and Tumor Derived Organoids for Cancer Biology and Personalized Therapeutics

Monday, January 20 | 5:00PM - 7:00PM
Modeling Immunity into Organoid Systems
Room: British Ballroom

Speaker 3 of 4
Fred H. Gage, The Salk Institute for Biological Studies, USA
Enhanced Glial Corporation and Vascularization of Brain Organoids

Monday, January 20 | 5:00PM - 7:00PM
Modeling Immunity into Organoid Systems
Room: British Ballroom

Speaker 4 of 4
Sebastian M. Löbl, Heinrich Pette Institute Leibniz Institute for Experimental Virology, Germany
Short Talk: Lymphocytes and Angiocrine Signaling in Liver Regeneration

Monday, January 20 | 7:00PM - 7:00PM
On Own for Dinner


Tuesday, January 21 | 7:30AM - 8:30AM
Breakfast
Room: Pacific Ballroom


Tuesday, January 21 | 8:30AM - 11:30AM
Developmental Programs of Organoid Stem Cells for Therapy
Room: British Ballroom

Speaker 1 of 8
* Randolph Scott Ashton, University of Wisconsin, USA

Tuesday, January 21 | 8:30AM - 11:30AM
Developmental Programs of Organoid Stem Cells for Therapy
Room: British Ballroom

Speaker 2 of 8
Takanori Takebe, Cincinnati Children's Hospital Medical Center, Japan
Modeling Hepato-Biliary-Pancreatic Organogenesis towards Therapy

Tuesday, January 21 | 8:30AM - 11:30AM
Developmental Programs of Organoid Stem Cells for Therapy
Room: British Ballroom

Speaker 3 of 8
Todd C. McDevitt, Gladstone Institutes, USA
Axial Elongation of Caudalized Human PSC Organoids Mimics Neural Tube Development

Tuesday, January 21 | 8:30AM - 11:30AM
Developmental Programs of Organoid Stem Cells for Therapy
Room: British Ballroom


Coffee Break

Tuesday, January 21 | 8:30AM - 11:30AM
Developmental Programs of Organoid Stem Cells for Therapy
Room: British Ballroom

Speaker 5 of 8
Mitsuru Morimoto, RIKEN, Center for Developmental Biology, Japan
Canonical and Non-Canonical Wnt Signaling Coordinate Trachea Development in vivo and in vitro

Tuesday, January 21 | 8:30AM - 11:30AM
Developmental Programs of Organoid Stem Cells for Therapy
Room: British Ballroom

Speaker 6 of 8
Andres J. Garcia, Georgia Institute of Technology, USA
Synthetic Hydrogels as Engineered Niches for Organoids

Tuesday, January 21 | 8:30AM - 11:30AM
Developmental Programs of Organoid Stem Cells for Therapy
Room: British Ballroom

Speaker 7 of 8
Sarah Saxton, University of Washington, USA
Short Talk: Hepatoblast Organoids have Bipotential Fate in Engineered Liver Tissue

Tuesday, January 21 | 8:30AM - 11:30AM
Developmental Programs of Organoid Stem Cells for Therapy
Room: British Ballroom

Speaker 8 of 8
Catarina Brito, Instituto de Biologia Experimental e Tecnológica, Portugal
Short Talk: Modelling Neuronal Microenvironment Dynamics in Disease

Tuesday, January 21 | 11:30AM - 5:00PM
On Own for Lunch


Tuesday, January 21 | 11:30AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Tuesday, January 21 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Tuesday, January 21 | 4:30PM - 5:00PM
Coffee Available
Room: British/Columbia Foyer


Tuesday, January 21 | 5:00PM - 7:00PM
Metabolic Crosstalk with Organoids and the Environment
Room: British Ballroom

Speaker 1 of 5
* Nastaran Zahir, NCI, National Institutes of Health, USA

Tuesday, January 21 | 5:00PM - 7:00PM
Metabolic Crosstalk with Organoids and the Environment
Room: British Ballroom

Speaker 2 of 5
Ömer Hidir Yilmaz, Massachusetts Institute of Technology, USA
Dietary Control of Intestinal Stem Cells in Physiology and Disease

Tuesday, January 21 | 5:00PM - 7:00PM
Metabolic Crosstalk with Organoids and the Environment
Room: British Ballroom

Speaker 3 of 5
Boudewijn MT Burgering, Utrecht University, Netherlands
Interplay between Metabolic Identities in the Intestinal Crypt

Tuesday, January 21 | 5:00PM - 7:00PM
Metabolic Crosstalk with Organoids and the Environment
Room: British Ballroom

Speaker 4 of 5
William D. Rees, University of British Columbia, Canada
Short Talk: Colon-Derived Enteroids from Inflammatory Bowel Disease Patients have Dysregulated Endoplasmic Reticulum Stress Pathways that Drive Dendritic Cell Maturation

Tuesday, January 21 | 5:00PM - 7:00PM
Metabolic Crosstalk with Organoids and the Environment
Room: British Ballroom

Speaker 5 of 5
Elisabeth Gleisinger, Technical University of Munich, Germany
Short Talk: Mitochondrial Impairment Drives Intestinal Stem Cell Transition into Dysfunctional Paneth Cells Predicting Crohn’s Disease Recurrence

Tuesday, January 21 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, January 21 | 7:30PM - 10:00PM
Poster Session 2
Room: Pacific Ballroom


Wednesday, January 22 | 7:30AM - 8:30AM
Breakfast
Room: Pacific Ballroom


Wednesday, January 22 | 8:30AM - 11:30AM
Cancer Cell Organoids
Room: British Ballroom

Speaker 1 of 8
* Simon Andrew Hirota, University of Calgary, Canada

Wednesday, January 22 | 8:30AM - 11:30AM
Cancer Cell Organoids
Room: British Ballroom

Speaker 2 of 8
Herve Tiriac, University of California, San Diego, USA
Pancreatic Cancer Patient-Derived Organoids as a Tool for Personalized Medicine

Wednesday, January 22 | 8:30AM - 11:30AM
Cancer Cell Organoids
Room: British Ballroom

Speaker 3 of 8
Nicola Valeri, Institute of Cancer Research, UK
Patient-Derived Organoids: Promises, Hurdles and Potential Clinical Applications

Wednesday, January 22 | 8:30AM - 11:30AM
Cancer Cell Organoids
Room: British Ballroom


Coffee Break

Wednesday, January 22 | 8:30AM - 11:30AM
Cancer Cell Organoids
Room: British Ballroom

Speaker 5 of 8
Claus Jorgensen, Cancer Research UK, UK
A Microenvironment Inspired Synthetic 3D Model for Pancreatic Ductal Adenocarcinoma

Wednesday, January 22 | 8:30AM - 11:30AM
Cancer Cell Organoids
Room: British Ballroom

Speaker 6 of 8
Shuibing Chen, Weill Cornell Medical College, USA
Human Pluripotent Stem Cells, Colonic Organoids and Colorectal Cancer

Wednesday, January 22 | 8:30AM - 11:30AM
Cancer Cell Organoids
Room: British Ballroom

Speaker 7 of 8
Karuna Ganesh, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Regenerative Origin of Metastasis Initiating Cells

Wednesday, January 22 | 8:30AM - 11:30AM
Cancer Cell Organoids
Room: British Ballroom

Speaker 8 of 8
Germain C. Ho, BC Cancer Research Centre, Canada
Short Talk: Single-Cell Sequencing of Normal Endometrial Organoids to Investigate Contribution of Secretory and Ciliated Cells to Endometrial Carcinomas

Wednesday, January 22 | 11:30AM - 5:00PM
On Own for Lunch


Wednesday, January 22 | 11:30AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Wednesday, January 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Wednesday, January 22 | 4:30PM - 5:00PM
Coffee Available
Room: British/Columbia Foyer


Wednesday, January 22 | 5:00PM - 7:00PM
Modeling Tissue Repair with Organoids
Room: British Ballroom

Speaker 1 of 6
* Andres J. Garcia, Georgia Institute of Technology, USA

Wednesday, January 22 | 5:00PM - 7:00PM
Modeling Tissue Repair with Organoids
Room: British Ballroom

Speaker 2 of 6
Konstantina Nikolakopoulou, University of Cambridge, UK
Organoids for the Study of Endometrial Physiology and Disease

Wednesday, January 22 | 5:00PM - 7:00PM
Modeling Tissue Repair with Organoids
Room: British Ballroom

Speaker 3 of 6
Thaddeus S. Stappenbeck, Cleveland Clinic, USA
Modeling the Mechanisms That Control Injury Cycles of Intestinal Epithelial Stem Cells

Wednesday, January 22 | 5:00PM - 7:00PM
Modeling Tissue Repair with Organoids
Room: British Ballroom

Speaker 4 of 6
Randolph Scott Ashton, University of Wisconsin, USA
Bioengineering Early CNS Morphogenesis for Scalable Assessment of Neural Tube Defect Risk

Wednesday, January 22 | 5:00PM - 7:00PM
Modeling Tissue Repair with Organoids
Room: British Ballroom

Speaker 5 of 6
Elisa M. Murray, Washington University in St. Louis, USA
Short Talk: Deciphering the Role of Her2 and Apc Mutations on the Intestinal Epithelium using Gastrointestinal Organoids

Wednesday, January 22 | 5:00PM - 7:00PM
Modeling Tissue Repair with Organoids
Room: British Ballroom

Speaker 6 of 6
Sakurako Kobayashi, Tokyo Medical and Dental University, Japan
Short Talk: Conceptual Basis of Lineage Shift between Intestinal Epithelium and Hepatocytes

Wednesday, January 22 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, January 22 | 7:30PM - 10:00PM
Poster Session 3
Room: Pacific Ballroom


Thursday, January 23 | 7:30AM - 8:30AM
Breakfast
Room: Pacific Ballroom


Thursday, January 23 | 8:30AM - 11:30AM
Engineering Solutions to Improve Organoid Growth
Room: British Ballroom

Speaker 1 of 8
* Todd C. McDevitt, Gladstone Institutes, USA

Thursday, January 23 | 8:30AM - 11:30AM
Engineering Solutions to Improve Organoid Growth
Room: British Ballroom

Speaker 2 of 8
Linda G. Griffith, Massachusetts Institute of Technology, USA
Integrating Synthetic Biomaterials and Perfusion to Enhance Organoid Function

Thursday, January 23 | 8:30AM - 11:30AM
Engineering Solutions to Improve Organoid Growth
Room: British Ballroom

Speaker 3 of 8
Sarah Heilshorn, Stanford University, USA
Protein-Engineered Materials as Synthetic Niches for Organoids

Thursday, January 23 | 8:30AM - 11:30AM
Engineering Solutions to Improve Organoid Growth
Room: British Ballroom


Coffee Break

Thursday, January 23 | 8:30AM - 11:30AM
Engineering Solutions to Improve Organoid Growth
Room: British Ballroom

Speaker 5 of 8
Zev Gartner, University of California, San Francisco, USA
The Role of Self-Organization in the Maintenance and Breakdown of Tissue Structure during Breast Cancer Progression

Thursday, January 23 | 8:30AM - 11:30AM
Engineering Solutions to Improve Organoid Growth
Room: British Ballroom

Speaker 6 of 8
Jennifer A. Lewis, Harvard University, SEAS, USA
Ex Vivo Vascularization of Organoid-on-Chip Models and 3D Tissues

Thursday, January 23 | 8:30AM - 11:30AM
Engineering Solutions to Improve Organoid Growth
Room: British Ballroom

Speaker 7 of 8
Kevin Achberger, University of Tuebingen, Germany
Short Talk: Retina-on-a-Chip- An in vitro Tool to Study the Complexity of the Human Retina

Thursday, January 23 | 8:30AM - 11:30AM
Engineering Solutions to Improve Organoid Growth
Room: British Ballroom

Speaker 8 of 8
Katarina Klett, Stanford University, USA
Short Talk: Tunable Engineered Matrix for the Culture of Human Intestinal Organoids

Thursday, January 23 | 11:30AM - 5:00PM
On Own for Lunch


Thursday, January 23 | 3:00PM - 4:30PM
Workshop II
Room: British Ballroom

Speaker 1 of 6
* Mark Kennedy, Thermo Fisher Scientific, USA

Thursday, January 23 | 3:00PM - 4:30PM
Workshop II
Room: British Ballroom

Speaker 2 of 6
Bo Yu, University of Washington, USA
Establishing Acute Infection in a Fallopian Tube Organoid Model

Thursday, January 23 | 3:00PM - 4:30PM
Workshop II
Room: British Ballroom

Speaker 3 of 6
Claudia Beaurivage, University of Sheffield, Netherlands
Establishment of a High Throughput Microfluidic Gut-on-a-Chip Model using Human Intestinal Organoids to Assess Compound Efficacy and Perform Target Validation in Inflammatory Bowel Disease

Thursday, January 23 | 3:00PM - 4:30PM
Workshop II
Room: British Ballroom

Speaker 4 of 6
Yoonseok Choi, University of Ulsan, South Korea
Development of an ex vivo Microfluidic Platform that Enabled the Preclinical Immune Response Interaction Monitoring followed by the Immune Checkpoint Blockade

Thursday, January 23 | 3:00PM - 4:30PM
Workshop II
Room: British Ballroom

Speaker 5 of 6
Jose Fabian Oceguera-Yanez, Kyoto University, Japan
Applications of Genetically Engineered Human iPSCs to Understand Skin Cancer Development and Pathology

Thursday, January 23 | 3:00PM - 4:30PM
Workshop II
Room: British Ballroom

Speaker 6 of 6
H.-H. Greco Song, Massachusetts Institute of Technology, USA
Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues

Thursday, January 23 | 4:30PM - 5:00PM
Coffee Available
Room: British/Columbia Foyer


Thursday, January 23 | 5:00PM - 6:45PM
Integrating Vasculature, Nerve Networks, and Dynamic Behavio
rs into Organoids

Room: British Ballroom

Speaker 1 of 5
* Thomas Åskov Pedersen, Novo Nordisk, Denmark

Thursday, January 23 | 5:00PM - 6:45PM
Integrating Vasculature, Nerve Networks, and Dynamic Behavio
rs into Organoids

Room: British Ballroom

Speaker 2 of 5
Michael A. Helmrath, Cincinnati Children's Hospital, USA
Integrating Models of Human Intestinal Development

Thursday, January 23 | 5:00PM - 6:45PM
Integrating Vasculature, Nerve Networks, and Dynamic Behavio
rs into Organoids

Room: British Ballroom

Speaker 3 of 5
Roger D. Kamm, Massachusetts Institute of Technology, USA
Microphysiological Models of Neurological Disease

Thursday, January 23 | 5:00PM - 6:45PM
Integrating Vasculature, Nerve Networks, and Dynamic Behavio
rs into Organoids

Room: British Ballroom

Speaker 4 of 5
Peter W. Zandstra, University of British Columbia, Canada
Engineering Stem Cell Fate and Function

Thursday, January 23 | 5:00PM - 6:45PM
Integrating Vasculature, Nerve Networks, and Dynamic Behavio
rs into Organoids

Room: British Ballroom

Speaker 5 of 5
Adrianna K. San Roman, Whitehead Institute, USA
Short Talk: Cell-Autonomous Effects of Sex Chromosome Dosage on Global Gene Expression

Thursday, January 23 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: British Ballroom


Thursday, January 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, January 23 | 8:00PM - 11:00PM
Entertainment
Room: Pacific Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Friday, January 24 | 10:24AM - 10:24AM
Departure


*Session Chair.

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