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Tuesday, November 19 | 4:00PM - 8:00PM
Arrival and Registration
Room: Imperial Ballroom Foyer


Tuesday, November 19 | 6:00PM - 8:00PM
Welcome Mixer
Room: Imperial Ballroom Terrace
No registration fees are used to fund alcohol served at this function.

Wednesday, November 20 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Imperial Ballroom

Speaker 1 of 2
* Karina R. Bortoluci, Federal University of São Paulo, Brazil

Wednesday, November 20 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Imperial Ballroom

Speaker 2 of 2
Kim Newton, Genentech, Inc., USA
The Cut that Makes the Difference – A Caspase-8 Story



Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 1 of 7
* Jonathan C. Kagan, Boston Children's Hospital, USA

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 2 of 7
Hao Wu, Harvard Medical School, Boston Children's Hospital, USA
Inflammasomes: NLRP3 and Gasdermin D (GSDMD)

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom


Coffee Break

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 4 of 7
Veit Hornung, Ludwig-Maximilians-University Munich, Germany
Inflammasome Signaling in the Human System

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 5 of 7
Daniel Kastner, National Institutes of Health, USA
Inflammasomes in Auto-Inflammatory Diseases

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 6 of 7
Niklas A. Schmacke, Ludwig-Maximilians-University Munich, Germany
Short Talk: Priming Enables a NEK7-Independent Route of NLRP3 Activation


Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 7 of 7
Bart Tummers, St. Jude Children's Research Hospital, USA
Short Talk: A Non-Apoptotic Function of Caspase-8 Mediates Inflammation and Blocks the Development of ALPS

Wednesday, November 20 | 12:00PM - 5:00PM
On Own for Lunch


Wednesday, November 20 | 12:00PM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Wednesday, November 20 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 1 of 8
* Russell E. Vance, University of California, Berkeley, USA

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 2 of 8
Youssef Aachoui, University of Arkansas for Medical Sciences, USA
Innate Lymphocytes Prime Caspase-11 in Neutrophils to Defend against a Cytosol Invasive Bacterium


Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 3 of 8
Thomas Burke, University of California, Berkeley, USA
Inflammasome-Mediated Antagonism of Type I Interferon Enhances Rickettsia Pathogenesis

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 4 of 8
Laura Migliari Branco, University of São Paulo, Brazil
Molecular Mechanisms Involved in NAIP/NLRC4 Inflammasome Activation


Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 5 of 8
Alejandro Rodriguez Gama, Stowers Institute for Medical Research, USA
The Inflammasome-Nucleating Interactome Reveals Specificity and Crosstalk in Cell Death Signaling

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 6 of 8
Lucas Secchim Ribeiro, University of Bonn, Germany
Inflammasome Activation and Pyroptosis Drive the Formation of Nuclear Filaments between Macrophages

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 7 of 8
Kateryna Shkarina, University of Lausanne, Switzerland
Optogenetic Control of Programmed Cell Death Reveals Differential Responses towards Apoptotic and Necrotic Cells

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 8 of 8
Monica Varela, Leiden University, Netherlands
Mycobacteria Exploit Host Caspase 11 and Gasdermin D Tandem for Phagosome Permeabilization, Macrophage Pyroptosis and Infection Dissemination

Wednesday, November 20 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 1 of 6
* Domagoj Vucic, Genentech, Inc., USA

Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 2 of 6
Feng Shao, National Institute of Biological Sciences, China
Mechanism and Function of Gasdermin-Mediated Pyroptosis

Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 3 of 6
Eicke Latz, University of Bonn, Germany
Cellular Responses to Pyroptosis

Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 4 of 6
Oliver Florey, Babraham Institute, UK
Eaten Alive! - Mechanisms and Consequences of Cell Cannibalism

Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 5 of 6
Catherine L. Day, University of Otago, New Zealand
Short Talk: Regulation of Ubiquitin Transfer by TRAF E3 Ligases


Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 6 of 6
Megan H. Orzalli, University of Massachusetts Medical School, USA
Short Talk: Apoptotic Caspases Activate Pro-Inflammatory Cell Death Pathways in Barrier Epithelial Cells

Wednesday, November 20 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace
No registration fees are used to fund alcohol served at this function.

Wednesday, November 20 | 7:30PM - 10:00PM
Poster Session 1
Room: Imperial Ballroom


Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 1 of 9
* Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 2 of 9
Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia
Towards Targeting Mutant p53 for Cancer Therapy

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 3 of 9
Henning Walczak, University College London, Cancer Institute, UK
Cell Death and Ubiquitin in Cancer

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom


Coffee Break

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 5 of 9
Ricardo Weinlich, Hospital Israelita Albert Einstein, Brazil
Necroptosis, Inflammation and Cancer

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 6 of 9
Ruth M. Kluck, Walter and Eliza Hall Institute of Medical Research, Australia
BAK and BAX in Cancer

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 7 of 9
Gabriela Brumatti, Walter and Eliza Hall Institute, Australia
Short Talk: RIPping Leukaemias Apart: The Role of RIP Kinase 1 in Acute Myeloid Leukaemia


Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 8 of 9
Dhyan Chandra, Roswell Park Comprehensive Cancer Center, USA
Short Talk: Novel Nuclear-Mitochondrial Crosstalk Regulates Cell Death and Survival in Cancer

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 9 of 9
Eli Arama, Weizmann Institute of Science, Israel
Short Talk: Parthanatos Steps Out of the Shadows of Cell Death and into the Developmental Spotlight


Thursday, November 21 | 11:45AM - 5:00PM
On Own for Lunch


Thursday, November 21 | 11:45AM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Thursday, November 21 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Thursday, November 21 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 1 of 7
* Kim Newton, Genentech, Inc., USA

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 2 of 7
Vishva M. Dixit, Genentech, Inc., USA
The Non-Canonical Inflammasome Pathway

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 3 of 7
Jonathan C. Kagan, Boston Children's Hospital, USA
Regulation of Innate Immunity

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 4 of 7
John Silke, Walter and Eliza Hall Institute of Medical Research, Australia
Mutations that Prevent Caspase Cleavage of RIPK1 Cause Inflammatory Disease

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 5 of 7
Konrad Aden, University Hospital Kiel, Germany
Short Talk: XBP-1 Coordinates DNA Damage Induced Stem Cell Repression in the Intestinal Epithelium via p53-Ddit4l-Dependent mTOR Inhibition

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 6 of 7
Randal Halfmann, Stowers Institute for Medical Research, USA
Short Talk: Waiting to Die: Signalosome Nucleation Kinetically Controls Cell Fate


Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 7 of 7
Caitlin Schneider, McGill University, Canada
Short Talk: Migration-Induced Cell Shattering Due to DOCK8 Deficiency Causes a Type-2 Biased T Helper Response

Thursday, November 21 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace
No registration fees are used to fund alcohol served at this function.

Thursday, November 21 | 7:30PM - 10:00PM
Poster Session 2
Room: Imperial Ballroom


Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 1 of 8
* Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 2 of 8
Petr Broz, University of Lausanne, Switzerland
Cell Death during Bacteria Infections

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 3 of 8
Ricardo T. Gazzinelli, Fundação Oswaldo Cruz-CPqRR, Brazil
Caspase 8 Mediates Experimental Cerebral Malaria

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom


Coffee Break

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 5 of 8
Russell E. Vance, University of California, Berkeley, USA
Inflammasome-Dependent Cell Death in Response to Bacterial Pathogens

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 6 of 8
Karina R. Bortoluci, Federal University of São Paulo, Brazil
Inflammasomes: Cell Death, Cytokines and Beyond

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 7 of 8
Katie Deets, University of California, Berkeley, USA
Short Talk: Investigating a Role for the NAIP/NLCR4 Inflammasome in Adaptive T Cell Responses

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 8 of 8
Sergio Costa Oliveira, Universidade Federal de Minas Gerais, Brazil
Short Talk: Guanylate-Binding Protein 5 Licenses Caspase-11 for Gasdermin-D Mediated Host Resistance to Intracellular Bacterial Infection

Friday, November 22 | 11:30AM - 5:00PM
On Own for Lunch


Friday, November 22 | 11:30AM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Friday, November 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Friday, November 22 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 1 of 7
* Ricardo T. Gazzinelli, Fundação Oswaldo Cruz-CPqRR, Brazil

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 2 of 7
Edward A. Miao, University of North Carolina at Chapel Hill, USA
Infectious Models Reveal a Unique Role for Caspase-7 after Cytotoxic Lymphocyte Attack

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 3 of 7
Dario S. Zamboni, University of São Paulo, Brazil
Inflammasomes in Host Response to Pathogenic Microbes

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 4 of 7
Larissa D. Cunha, Ribeirao Preto Medical School, University of Sao Paulo, Brazil
Short Talk: Regulation of Macrophage Function by LC3-Associated Phagocytosis


Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 5 of 7
Marcel Doerflinger, Walter and Eliza Hall Institute, Australia
Short Talk: Functional Overlap of Different Cell Death Pathways Ensures Host Protection against Intracellular Bacterial Pathogens

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 6 of 7
Antonia R. Bass, University of Pennsylvania, USA
Short Talk: Human Noncanonical Inflammasome Responses to Legionella Pneumophila

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 7 of 7
Kshiti Meera Phulphagar, Max Planck Institute of Biochemistry, Germany
Short Talk: Quantitative Spatial Proteomics Reveals Specific Nlrp3 and Cell Death Mediated Reprogramming of Essential Cellular Functions and Organelles

Friday, November 22 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace
No registration fees are used to fund alcohol served at this function.

Friday, November 22 | 7:30PM - 10:00PM
Poster Session 3
Room: Imperial Ballroom


Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 1 of 10
* Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 2 of 10
Andrew W. Roberts, Walter and Eliza Hall Institute of Medical Research, Australia
Translational and Clinical Updates on Targeting BCL2 and MCL-1

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 3 of 10
Ksenija Slavic Obradovic, Boehringer Ingelheim RCV GmBH & Co KG, Austria
Short Talk: Enabling Cell Death: Genetic Dissection of Cellular Responses to SMAC Mimetic Treatment

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 4 of 10
Opher Shai Kornfeld, Genentech, Inc., USA
Short Talk: IRF2 Transcriptionally Induces GSDMD Expression for Pyroptosis

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom


Coffee Break

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 6 of 10
Domagoj Vucic, Genentech, Inc., USA
Regulation of Inflammatory Cell Death Signaling by RIP Kinases

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 7 of 10
Wenlin Shao, AstraZeneca, USA
Broad Opportunity of Cell Death Agents as Mono- and Combination Therapies in Haematological and Solid Cancers

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 8 of 10
Pedro Elias Marques, KU Leuven, Belgium
Short Talk: Displacement of Necrotic Cell Debris In Vivo by a Chemokine-Based Peptide Dampens Tissue Inflammation

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 9 of 10
Jun Sun, University of Illinois at Chicago, USA
Short Talk: Intestinal Vitamin D Receptor Determines Cell Fate via Apoptosis and Autophagy

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 10 of 10
Lynn Wong, University of Zurich, Switzerland
Short Talk: TNFR2 Induced Priming of NLRP3-Inflammasome via RIPK1 Leads to Pyroptosis in XIAP Deficient Cells

Saturday, November 23 | 11:45AM - 5:00PM
On Own for Lunch


Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 1 of 8
* Laura D. Attardi, Stanford University School of Medicine, USA

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 2 of 8
Silvina Odete Bustos, Instituto do Câncer do Estado de São Paulo, Brazil
A New Imidazacridine Derivate with Antineoplasic Activity in Melanoma


Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 3 of 8
Annette Jacobsen, Walter and Eliza Hall Institute, Australia
Up Close and Personal with the Necroptotic Death Effector, MLKL: Lessons Learned from Mutagenesis Studies

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 4 of 8
Bruna dos Santos Mendonça, Brazilian National Cancer Institute, Brazil
Nuclear Localization of X-Linked Inhibitor of Apoptosis Protein (XIAP): Impact on Drug Resistance, Cell Growth and Prognosis in Breast Cancer

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 5 of 8
Ancely F. dos Santos, University of São Paulo, Brazil
Ferroptosis Contributes to MB-PDT Efficacy on Killing Human PDAC Cells

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 6 of 8
Maria Tanzer, Max Planck Institute of Biochemistry, Germany
Phosphoproteome and Secretome Analysis Reveal Differences between TNF-Induced Apoptosis and Necroptosis

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 7 of 8
Angelica Beate Winter Boldt, Universidade Federal do Paraná, Brazil
At the Edge of Survival: Genetic Associations for Cell Death in Pemphigus Foliaceus


Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 8 of 8
Mikaela Catherine Coleman, University of Sydney, Australia
Dissecting the Ways to Die: A Single-Cell Assay to Simultaneously Quantify Cell Loss and Discriminate Death Program

Saturday, November 23 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Saturday, November 23 | 5:00PM - 5:45PM
Keynote Address
Room: Imperial Ballroom

Speaker 1 of 2
* Vishva M. Dixit, Genentech, Inc., USA

Saturday, November 23 | 5:00PM - 5:45PM
Keynote Address
Room: Imperial Ballroom

Speaker 2 of 2
Shigekazu Nagata, IFReC, Osaka University, Japan
Phosphatidylserine-Dependent Efferocytosis and Entosis

Saturday, November 23 | 5:45PM - 7:15PM
Cell Death in Inflammatory Diseases
Room: Imperial Ballroom

Speaker 1 of 4
* John Silke, Walter and Eliza Hall Institute of Medical Research, Australia

Saturday, November 23 | 5:45PM - 7:15PM
Cell Death in Inflammatory Diseases
Room: Imperial Ballroom

Speaker 2 of 4
Francis Ka-Ming Chan, Duke University, USA
RIPK3 in Anti-Viral Immunity and Tissue Homeostasis

Saturday, November 23 | 5:45PM - 7:15PM
Cell Death in Inflammatory Diseases
Room: Imperial Ballroom

Speaker 3 of 4
Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Regulation of Inflammasome Activation and Cell Death

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