Tissue Plasticity: Preservation and Alteration of Cellular Identity Organizer(s): Ophir Klein, Ramesh A. Shivdasani and Stacey S. Huppert Date: October 05 - 07, 2020
Location: Virtual at your computerFor important information on the coronavirus, please click hereCellular plasticity, the ability to acquire new identities or adopt alternative fates, occurs in normal physiology and disease states. Researchers are just beginning to understand how plasticity contributes to homeostasis and regeneration in the setting of tissue injury. Alterations in cell fate can be harnessed to treat disease, but uncontrolled plasticity can destabilize cell commitment and contribute toward neoplasia. The cellular and molecular underpinnings of cellular plasticity provide insights into disease processes and enable new therapies. This conference will explore the diverse mechanisms that underlie plasticity in different tissues and contexts. By bringing together leading scientists in stem cell, developmental, regenerative, and cancer biology, this interdisciplinary conference will highlight common principles and unique features of cellular plasticity in different tissues and examine the therapeutic potential of this process. The conference represents a unique opportunity for researchers in diverse fields to visit evolving concepts in cellular plasticity and the molecular mechanisms and physiological consequences of altered adult cell identity in vivo. While the topic has been included marginally at other conferences (i.e., conferences on stem cell biology, regeneration, epigenetics, and cancer) only this Keystone Symposia conference, first held in 2019, has focused on cellular plasticity across mammalian tissues. This conference will assemble speakers from diverse disciplines and organ systems to identify cross-cutting themes and provide a forum for investigators to explore common underlying mechanistic principles and therapeutic potential. Global Health Travel Award Deadline: October 3 2020 Scholarship Deadline: October 3 2020 Abstract Deadline: September 14 2020 We gratefully acknowledge additional support for this conference from:  We gratefully acknowledge the generous grant for this conference provided by: National Institute of Dental and Craniofacial Research (NIDCR)Grant No. 1R13DE030021-01 Funding for this conference was made possible (in part) by 1R13DE030021-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government. |