Autophagy: Mechanisms and Disease - VIRTUAL CONTENT AVAILABLE ON DEMAND

Organizer(s): Patricia Boya, Felix Randow and Masaaki Komatsu

Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation
Sponsored by Astellas Pharma Inc., AstraZeneca and Cell Research

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Summary of Meeting:

Autophagy is an intracellular pathway for degradation that allows for the recycling of cellular components inside lysosomes to sustain tissue homeostasis. Countless effort has been devoted to help unravel the molecular mechanisms that regulate this pathway, but many questions remain unresolved. Therefore, this conference program gathers an interdisciplinary group of scientists to address the current and future challenges in the field such as discussions on the existence of non-canonical forms of the pathway and how selectivity is achieved. This conference also addresses the minimal requirements to generate functional autophagosomes and the molecular bases of autophagy regulation. One of the major themes of this conference is a session which reviews how model systems such as plants, worms and mice help to unravel the physiological roles of this essential pathway and why this research can also be applied to find new therapies for human diseases. For example, while it is now clear that many human pathologies have alterations in autophagy, how scientists could potentially manipulate the pathway in vivo is a major challenge that will be addressed at this conference. Finally, this conference provides a unique frame to display the current research and future challenges of the field during physiological and pathological conditions.

Global Health Travel Award Deadline: September 22 2020

Scholarship Deadline: September 22 2020

Abstract Deadline: September 14 2020

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA254442-01
Funding for this conference was made possible (in part) by 1R13CA254442-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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